Prednisolone

What is Prednisolone for?

Prednisolone belongs to a class of medicines called corticosteroids. Corticosteroids are hormones that are found naturally in your body and help to keep you healthy and well. Prednisolone can help reduce inflammation and reduce symptoms of swelling, redness, and itchiness.

Prednisolone can also be used to treat conditions such as:

• Asthma
• Allergic conditions
• Skin problems such as eczema, psoriasis (a skin disease that causes red itchy scaly patches) and bullous pemphigoid (a condition where the skin develops large itchy blisters that are filled with fluid)
• Different diseases affecting the immune system such as Lupus
• Joint problems such as rheumatoid arthritis (an immune condition causing joint pain and joint damage) and gout
• Nephrotic syndrome, a condition where the kidney releases too much protein into the urine

This medication may also be given as a replacement if the body does not produce enough corticosteroid hormones.

You can also find out about this medication by watching these videos:

They are available in English, 中文, Melayu and தமிழ்: Prednisolone

How should I take or use Prednisolone?

• Do not stop taking your medication without checking with your healthcare professional. You may need to slowly reduce the dose taken before stopping the medication completely.
• Take this medication with or after food to prevent stomach upset.
• Do not take more medication than prescribed as this may increase your risk of experiencing side effects.

What should I do if I forget to take or use Prednisolone?

If you forget to take a dose, take it as soon as you remember. Then take your next dose at the usual time. Do not take two doses to make up for the missed dose. 

What precautions should I take when taking or using Prednisolone?

Inform your healthcare professional if: 
 

• You are allergic to this medication or any of the other ingredients of this medication
• You are pregnant, planning to become pregnant, or breastfeeding 
• You are taking any other medications, including supplements, traditional medications and herbal remedies. 
• You have any of the following conditions
  • Tuberculosis or other infections
  • Stomach ulcer
  • Severe depression
  • Diabetes
  • High blood pressure
  • Kidney, liver, heart or thyroid problems
  • Osteoporosis where you have thin or brittle bones
  • Any form of cancer
  • Glaucoma (a type of eye condition linked to increased pressure in the eye)
• You are planning to receive any vaccinations
• You are going for surgery or skin tests
   

You may get infections more easily while being treated with this medication. Avoid crowded places or being near people who are sick. Avoid close contact with people who have chicken pox, shingles or measles. See a doctor if you develop fever, sore throat or other signs of infection.

What food or medication should I avoid when I take or use Prednisolone?

Avoid taking alcohol with this medication to reduce the chance of an upset stomach.

If your doctor has put you on a low salt diet, follow this dietary instruction strictly. This is usually done to prevent excessive water retention.

What are some common side effects of Prednisolone?

• Upset stomach, nausea or vomiting
  • Take this medication after food to reduce chances of an upset stomach.
• Unable to sleep or feeling restless
  • Do not take this medication at night, try to take it earlier in the day or afternoon.
• Water retention, increase in weight
• Muscle weakness or cramps (with long term use)
• Easy bruising

Inform the doctor if any of the above side effects lasts for more than a few days or if they become severe.

What are some rare but serious side effects that I need to seek medical advice immediately?

The symptoms of a drug allergy include one or more of the following: 

• Swollen face/eyes/lips/tongue
• Difficulty in breathing
• Itchy skin rashes over your whole body

If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.

You can also find out about drug allergies by watching these videos:
They are available in English, 中文, Melayu and தமிழ்: Drug Allergies

Other rare but serious effects that may occur include: 

• Signs of infection, such as fever, chills, sore throat, mouth sores or wounds that will not heal
• Signs of high blood sugar, such as confusion, feeling very tired, increased thirst, increased hunger, passing urine more often, flushing or fast breathing 
• Very bad stomach pain
• Swelling, warmth, numbness, changes in colour or pain affecting the legs or arms
• Changes in vision 
• Bone pain or fractures 
• Sudden mood changes like feeling depressed, anxious, fluctuating feelings
• Abnormal bruising or bleeding, including black tarry or bloody stools or vomiting 

If you experience any of these symptoms, you should see your healthcare professional immediately.

How should I store Prednisolone?

Store in a cool and dry place, away from direct sunlight. Keep this medication away from children.

How do I throw away Prednisolone safely?

Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.