Symptoms arising from pancreatic tumours depend on their location. In the case of PNET, it also depends on whether the tumours are functional, ie if they produce excessive hormones which cause clinical syndromes. Tumours in the head of pancreas may cause jaundice, pain and vomiting. Tumours arising from the neck, body and tail of pancreas may be silent when small, and only produce symptoms of pain and discomfort when they get bigger.
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