• Randomised, double-blind, placebo-controlled, parallel-group, 12-month trial of leuco-methylthioninium bis (bydromethanesulfonate) in subjects with mild to moderate alzhiemer’s disease- principal investigator (Dept of Psy Med, CGH) from Dec 2013 to Jun 2015
• An exploratory placebo-controlled, dose-ranging study of the effects of methythioninium chloride 30 mg tid, 60 mg tid and 100 mg tid in patients with mild to moderate dementia of alzheimer type, co-investigator, 2007 to 2009
• National community mental health prevalence study of depression, anxiety and dementia in the elderly, co-investigator, 2003 to 2004