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Prof Chandran Manju

MD, FACP, FACE, FAMS, CCD

Senior Consultant

Singapore General Hospital

Specialty: Endocrinology, Endocrinology

Sub-specialties: Complicated Osteoporosis, General Endocrinology, Diabetes, Metabolic Bone Disorders

Conditions Treated by this Doctor:
Diabetes Mellitus, Metabolic Bone Diseases, Osteoporosis, Osteoporosis, Thyroid Disorders.

Clinical Appointments

Senior Consultant Endocrinology Singapore General Hospital

Profile

Senior Consultant and Director of the Osteoporosis and Bone Metabolism Unit which she set up in 2008.

Education

Fellowship in Endocrinology and Metabolism from University of California San Diego School of Medicine, USA

Professional Appointments and Committee Memberships

Senior Consultant and Director, Osteoporosis and Bone Metabolism Unit, Department of Endocrinology, Singapore General Hospital
Clinical Professor, DUKE NUS Medical School
Chairperson, Asia Pacific Consortium on Osteoporosis (APCO),
Elected Member of the Board and of the Committee of Scientific Advisors of the International Osteoporosis Foundation (IOF)
Chairperson, Asia Pacific Panel of the International Society of Clinical Densitometry (ISCD)
Deputy Chairperson, Asia Pacific Regional Advisory Council of the IOF
Appointed Member of the Bone Health Expert Group of the World Health Organization (WHO)
Past Chairperson, Chapter of Endocrinology, College of Physicians, Academy of Medicine Singapore
Past President, Endocrine and Metabolic Society of Singapore (EMSS)
Treasurer, Osteoporosis Society Singapore
Chairperson, Singapore Agency for Care Effectiveness Guidance on Osteoporosis Identification and Management in Primary Care Working Group.

Awards

International Society of Clinical Densitometry (ISCD) 2023 International Clinician of the Year Award
International Osteoporosis Foundation (IOF) Olof Johnell Science Award 2021 given in recognition of contributions at global level to the musculoskeletal field
International Osteoporosis Foundation CNS (Committee of National Societies) Medal of Excellence 2015
Gold Star Award Winner for the SGH OPTIMAL Program in the Global Map of Best Practice of the Capture the Fracture Campaign of the International Osteoporosis Foundation 2015
International Osteoporosis Foundation- World Congress on Osteoporosis International Young Investigator Award 2013
Service with a Heart Award 2008, 2009, 2011, 2021
Singapore General Hospital Most Inspiring Mentor Award 2021
Singhealth DUKE NUS Most Caffeinated Researcher Award 2019

Research Interests

Epidemiology and Health Economics of Osteoporosis
Rare Bone Disorders
Secondary Osteoporosis
Metabolic Bone Disorders
Diabetes and Osteoporosis
Artificial Intelligence in Osteoporosis

Publications

Selected out of 200+ publications

Cost-Effectiveness of FRAX® based Intervention Thresholds for Management of Osteoporosis in Singaporean Women. Chandran M, Ganeshan G, Tan KB, Hiligsmann M, Reginster JY. Osteoporos Int, 2021.Apr;32(4):787-789
Development of the Asia Pacific Consortium on Osteoporosis (APCO) Framework: clinical standards of care for the screening, diagnosis, and management of osteoporosis in the Asia-Pacific region. Chandran M et al. Osteoporos Int. Jan 27 2021. doi: 10.1007/s00198-020-05742-0
Improving care pathways for people living with rare bone diseases (RBDs): outcomes from the first RBD Summit. Chandran M et al. Osteoporos Int. 2023 Jun 9. doi: 10.1007/s00198-023-06791-x.
Fracture Risk Assessment in Clinical Practice: Why Do It? What to Do It With? Chandran M.J Clin Densitom. 2017 Jul - Sep;20(3):274-279
Diabetes Drug Effects on the Skeleton.Chandran M. Calcif Tissue Int. 2017 Feb;100(2):133-149.
Mechanisms of diabetes mellitus-induced bone fragility. Napoli N, Chandran M, Pierroz DD, Abrahamsen B, Schwartz AV, Ferrari SL; IOF Bone and Diabetes Working Group.Nat Rev Endocrinol. 2017 Apr;13(4):208-219
A Retrospective Review of Imaging and Operative Modalities Performed in Patients with Primary Hyperparathyroidism at a Mid-Volume Surgical Centre in Southeast Asia.Tan MZ, Ng JC, Eisman JA, Ng DC, Hansen L, Chandran M. Ann Acad Med Singapore. 2016 May;45(5):191-7.
Surgery or no surgery: What works best for the kidneys in primary hyperparathyroidism? A study in a multi-ethnic Asian population.Tay YK, Khoo J, Chandran M. Indian J Endocrinol Metab. 2016 Jan-Feb;20(1):55-61
AXIAL BMD IN DIABETIC AND NONDIABETIC SOUTHEAST ASIANS WITH HIP FRACTURES: DO RACE AND BODY MASS INDEX MATTER? Chandran M, Tay D, Tan M, Hao Y, Huang XF, Khoo J, Puar TH. Endocr Pract. 2016 Jun;22(6):716-25

Lead Investigator in the Evolution of Trabecular Bone Score following Renal Transplantation funded by the Lee Foundation Singhealth Transplant Grant.

Lead Investigator in the Development of Normative Ranges for Trabecular Bone Score for Singaporeans Research Study funded by the AM/ACP Designated Philanthropic fund