Trimetazidine

Vastarel


Uses


What is Trimetazidine for?

Trimetazidine belongs to the class of medications called fatty acid oxidation inhibitors. It is used to prevent and treat the symptoms of angina (chest pain). Angina is caused by lack of blood supply and oxygen to your heart. Trimetazidine helps to maintain the energy metabolism of heart muscle cells, protecting them from the effects of reduced oxygen supply.

When you take this medication regularly on a long term basis, it can help treat angina by reducing the number of times you get angina.

How should I take or use Trimetazidine?

  • Do not stop taking your medication without checking with your healthcare professional. If you stop taking your medication, you may experience a worsening of your condition.
  • This medicine should be taken with or after food.

What should I do if I forget to take or use Trimetazidine?

If you forget to take a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose. Then take your next dose at the usual time. Do not take two doses to make up for the missed dose.


Precaution


What precautions should I take when taking or using Trimetazidine?

Inform your healthcare processional if:

  • You are allergic to this medication or any of the other ingredients of this medication.
  • You are pregnant, planning to become pregnant, or breastfeeding.
  • You have kidney problems.
  • You have Parkinson's disease, tremors, restless leg syndrome or other related movement disorders.
  • You are taking any other medications, including supplements, traditional medications and herbal remedies

Side Effects


What are some common side effects of Trimetazidine?

  • Nausea, vomiting
  • Abdominal pain, indigestion
  • Diarrhoea
  • Dizziness
  • Headache
  • Feeling weak
  • Rashes

Inform your healthcare professional of these side-effects do not go away and interfere with your daily life.

Rare but serious side effects that need to seek medical advice immediately

Very rarely, trimetazidine may cause movement disturbances. These symptoms may include one or more of the following:

  • Trembling
  • Unsteady gait
  • Uncontrolled body movement

The symptoms of a drug allergy include one or more of the following:

  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

If your experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.


Handling


How should I store Trimetazidine?

  • Keep away from children
  • Keep in a cool, dry place, away from direct sunlight
  • Throw away all expired medications.

How do I throw away Trimetazidine safely?

Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.


For more information


What should I do if I overdose?

If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare processional for more information.

Disclaimers

Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.

If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System, and SingHealth), community pharmacies (Guardian, Unity, and Watsons), and the Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.

Last Updated on November 2020



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