Oxcarbazepine

Trileptal , Oxcarbazepine


Uses


What is Oxcarbazepine for?

Oxcarbazepine is used to control some types of seizures (commonly known as fits).

How should I take or use Oxcarbazepine?

Follow the instructions on your medicine label and take the medicine as prescribed by your doctor. To reduce stomach discomfort, you can take this medication after food.

You may not experience any effect immediately after starting the medication as it may take up to a few weeks before this medication can exert its full effects. You should continue to take your medicines regularly as instructed by your doctor even if you feel well. Stopping your medicines without informing your healthcare professionals may cause your condition to become worse quickly.

Do not stop taking or adjust the dose of this medication without consulting your healthcare professionals. Do not change brands or dosage forms of the medication without informing your healthcare professional

What should I do if I forget to take or use Oxcarbazepine?

If you miss a dose, take the missed dose as soon as you remember. If it is almost time for your next dose, take only the usual dose. Do not double your dose or use extra medicine to make up for the missed dose.


Precaution


What precautions should I take when taking or using Oxcarbazepine?

Stevens-Johnson syndrome (SJS) or toxic epidermal necrolysis (TENS) are rare and serious skin reactions which can happen after using particular medications. Symptoms include face swelling, blisters on skin, skin rashes that spreads throughout the body within hours to days after taking the medication. It usually occurs within the first few months (monitor closely for the first 3 months) of treatment. Those who have been taking oxcarbazepine for more than 3 months without developing skin reactions are at low risk of SJS or TEN. As these skin reactions are rapidly progressing, caregivers should bring patient to emergency department if patient shows first sign of rash.

Inform your healthcare professionals if you have the following medical conditions before starting on oxcarbazepine:

  • Liver problems
  • Kidney problems
  • Heart problems
  • Blood-related diseases
  • Drug allergies to oxcarbazepine or carbamazepine

For women: Inform your healthcare professionals if you are pregnant, plan to become pregnant, or are breastfeeding.

Consult your healthcare professional immediately if your seizures get worse or become different after you start on this medication.

What food or medication should I avoid when I take or use Oxcarbazepine?

Inform your healthcare professional that you are on oxcarbazepine.

Oxcarbazepine may decrease the effectiveness of hormonal contraceptives (birth control pills, patches, rings, injections, implants or intrauterine devices). Discuss with your healthcare professionals regarding birth control while on oxcarbazepine.

Avoid drinking alcohol while taking this medicine.

Please consult your healthcare professionals before using any other medications, including over-the-counter medicines, vitamins and herbal products.


Side Effects


What are some common side effects of Oxcarbazepine?

Like all medicines, this medication may cause some possible side effects but not everyone experiences them. Consult your healthcare professionals if any of the side effects lasts more than a few days, or become severe and bothersome.

The common side effects of oxcarbazepine include:

  • Dizziness, feeling lightheaded, feeling clumsy, unsteady movements
    • Get up slowly from a sitting or lying down position
  • Drowsiness
    • Avoid driving, operating machinery or engaging in strenuous physical activities
    • Avoid taking over-the-counter medications (such as cold or allergy medications) that could also add on to the drowsiness, refer to a healthcare professional if needed
  • Diarrhoea or constipation
        • Drink more water
        • Taking more high-fibre foods and frequent exercise can help with constipation
  • Nausea, vomiting, loss of appetite, stomach upset
    • Take the medicine with or after food to reduce nausea and vomiting
    • Avoid food that is too rich, spicy or has strong smells
  • Headache, back pain
    • Use of paracetamol can help to relieve headache or back pain

If the following serious side effects happen, you should go to the emergency department:

  • Red skin rash which spreads quickly and may blister or peel off
  • Persistent nausea, vomiting, confusion, tiredness
  • Fever, chills, sore throat, mouth ulcers or sores
  • Unusual bruising or bleeding
  • Dark coloured urine or light-coloured stools, yellowing of your eyes or skin, severe loss of appetite, stomach pain, nausea, vomiting that does not go away
  • Feelings of confusion or unusual thoughts

The symptoms of a drug allergy include one or more of the following and requires an emergency department visit:

  • Swollen face / eyes / lips / tongue
  • Difficulty in breathing
  • Itchy skin rashes over your whole body

Handling


How should I store Oxcarbazepine?

  • Keep away from children
  • Keep in a cool, dry place, away from direct sunlight

How do I throw away Oxcarbazepine safely?

Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.


Other Languages


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Oxcarbazepine in Mandarin Chinese

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Disclaimers

Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.

If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System, and SingHealth), community pharmacies (Guardian, Unity, and Watsons), and the Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.

Last Updated on February 2020



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