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Drug Class: Commonly Known As: Category:
PARP Inhibitor Lynparza® Cancer-related

Olaparib - Side Effects, Precautions, and Contraindications

What side effects can Olaparib cause?

  • Nausea and vomiting
  • Diarrhea and/or stomach discomfort
  • Constipation
  • Decreased appetite and taste changes
  • Headache, bone, muscle or back ache
  • Fatigue
  • Rash
  • Decreased blood cells
    This may increase your chances of getting infections, bruising or bleeding. You may also feel tired with a general lack of energy; do avoid over-exerting yourself with strenous physical activities.

Inform your doctor if any of the following occurs:

  • Unhealthy pale skin appearance, increasing tiredness or weakness, light-headedness
  • Persistent weight loss
  • Signs of infection – fever, chills, cough, sore throat
  • Unusual bruising or bleeding, black sticky stools or blood in the urine
  • Suden onset or worsening of cough with chest pain or breathing difficulty

Before taking Olaparib , what precautions must I follow?

  • Inform your doctor of pharmacist if you:
    • Have any other medical conditions e.g kidney or lung problems
    • Are taking any other medication, herbal products or supplements
  • Use effective birth control during and after stopping treatment for at least:
    • 1 month (for women)
    • 3 months (for men)

    Inform your doctor if you or your partner plan for or suspect pregnancy.

What food or medicine must I avoid when I take Olaparib ?

  • Avoid the following fruit and their juices while taking Olaparib:
    • Grapefruit
    • Pomelo
    • Seville orange

Olaparib - Additional Information

  • Updated on 10/11/2019 12:00:00 AM
  • Article contributed by Department of Pharmacy National Cancer Centre Singapore
The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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