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Megestrol

Drug Class: Commonly Known As: Category:
Progestin Megace® Cancer-related

Megestrol - What is it for

​Megestrol is a medication used to treat advanced breast cancer and endometrial (lining of the womb) cancer.

It may also be used to improve appetite in certain patients facing significant weight loss.

Megestrol - Side Effects, Precautions, and Contraindications

What side effects can Megestrol cause?

Megestrol is usually well tolerated and serious side effects are rare.

  • Weight gain, due to increased appetite
  • Nausea may occur inititally
    If this happens, take your tablets after food.

Inform your doctor if any of the following occurs:

  • Signs of a blood clot e.g. warmth, pain, redness and discoloration on arm or leg
  • Swelling of hands, feet or lower legs which causes discomfort
  • Sudden onset of cough, chest pain or shortness of breath
  • For women: Unexpected bleeding or discharge from the vagina

Before taking Megestrol, what precautions must I follow?

  • Inform your doctor or pharmacist if you have any other medical conditions e.g. history of blood clots, diabetes.
  • Inform your doctor if you are pregnant or breast-feeding: Megestrol should not be taken at the same time.

What food or medicine must I avoid when I take Megestrol?

Megestrol - Dosage and How to Use

How should Megestrol be used?

It is a tablet taken by mouth, with or without food. Take exactly as instructed by your doctor.

What should I do if I miss a dose?

If you miss a dose of Megestrol, take it as soon as you remember. However, if it is too near to your next dose, skip the missed dose and go back to your usual dosing time. Do not double dose. 

What should I do if I overdose?

​If you overdose on this medication, inform your doctor immediately.

Megestrol - Handling and Storage

How should I handle Megestrol safely?

How should I store Megestrol?

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#Store at room temperature;#

How should I dispose of Megestrol safely?

Megestrol - Additional Information

  • Updated on Monday, March 11, 2019
  • Article contributed by Department of Pharmacy National Cancer Centre Singapore

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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