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Letrozole

Drug Class: Commonly Known As: Category:
Aromatase Inhibitor Femara® Cancer-related

Letrozole - What is it for

Letrozole is a medicine that is used to treat breast cancer in menopausal women. It works by reducing the production of a hormone, estrogen that is present in the body.

Letrozole - Side Effects, Precautions, and Contraindications

What side effects can Letrozole cause?

  • Bone pain, joint pain or muscle ache
  • Hot flushes can sometimes occur
    If this occurs, take your tablets at bedtime.
  • Tiredness and lack of energy may occur
    If tiredness is a problem, do not drive a car or operate machinery if you are feeling tired. Avoid alcohol as it may make you feel more tired and drowsy.
  • Osteoporosis
    Calcium supplementation can reduce or prevent bone thinning.
  • Hair thinning may occur
    If this occurs, use a gentle baby shampoo and soft brush.

Inform your doctor if any of the following occurs:

  • Severe headache or nausea
  • Skin rash
  • Chest pain or palpitations
  • Dizziness
  • Swollen extremities
  • Unusual constipation or diarrhea
  • For women: Unexpected vagina bleeding or discharge

Before taking Letrozole, what precautions must I follow?

What food or medicine must I avoid when I take Letrozole?

Letrozole - Dosage and How to Use

How should Letrozole be used?

It is a tablet taken by mouth. It can be taken with food or on an empty stomach with a glass of water or juice.

What should I do if I miss a dose?

If you miss a dose of Letrozole, take it as soon as you can if it is within 12 hours of the missed dose. If it is over 12 hours since your missed dose, skip the missed dose and go back to your usual dosing time.

What should I do if I overdose?

If you overdose on this medicine, inform your doctor immediately.

Letrozole - Handling and Storage

How should I handle Letrozole safely?

How should I store Letrozole?

Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#Store at room temperature;#

How should I dispose of Letrozole safely?

Letrozole - Additional Information

Click here to learn more about Letrozole used as an oral fertility drug in women.

  • Updated on Thursday, October 19, 2017
  • Article contributed by Department of Pharmacy National Cancer Centre Singapore

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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