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Estrogen (Transdermal)

Drug Class: Commonly Known As: Category:
Estrogen Oestrogel, Divigel Adult

Estrogen (Transdermal) - What is it for

​It is used for the treatment of menopausal symptoms (hot flushes, excessive sweating, urinary symptoms, and vaginal dryness) or prevention of post-menopausal bone loss.

Estrogen (Transdermal) - Side Effects, Precautions, and Contraindications

What side effects can Estrogen (Transdermal) cause?

​The most common side effects include breast tenderness, headache, nausea, vomiting or even some skin irritation at site of application.

Consult your doctor about any symptom that becomes bothersome. Serious side effects such as blood clot formation are rare. However, report any severe pain or numbness in the arms, chest, and legs or feeling of breathlessness to your doctor.

Before taking Estrogen (Transdermal), what precautions must I follow?

What food or medicine must I avoid when I take Estrogen (Transdermal)?

Estrogen (Transdermal) - Dosage and How to Use

How should Estrogen (Transdermal) be used?

​There are two types of transdermal preparations available:

  • Oestrogel®

Apply topically to the skin of upper arms, lower trunk or the right or left thigh. Unless otherwise directed by the doctor, start applying with ½ ruler (1.25g) of the gel and slowly increase to 1 ruler (2.5g) of the gel daily.

  • Divigel®

Apply one sachet once dail​y, on the skin of the upper arms, lower trunk or the right or left thighs.

Application should be made at the same time each day. Do not apply over the breast or mucous membranes. After application, allow the gel to dry for a few minutes before dressing and do not wash the area for at least an hour. Please wash hands after each application.

What should I do if I miss a dose?

​If the dose is missed less than 12 hours, apply as soon as possible; if it is more than 12 hours, skip the dose and apply the next dose on the next day. Do not double the dose to make up for the missed dose.

Note: Missed doses may induce break through bleeding.

What should I do if I overdose?

Estrogen (Transdermal) - Handling and Storage

How should I handle Estrogen (Transdermal) safely?

How should I store Estrogen (Transdermal)?

Store at room temperature;#

How should I dispose of Estrogen (Transdermal) safely?

Estrogen (Transdermal) - Additional Information

​The doctor may or may not prescribe a progestogen depending on whether you have had a hysterectomy. If progestogen is prescribed, it is usually prescribed 12 – 14 days per cycle.

​Click here for more information on estrogen.

  • Updated on Monday, April 1, 2013
  • Article contributed by Pharmacy Department KK Women's and Children's Hospital

The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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