Epoetin Alfa

Eprex®


Uses


What is Epoetin Alfa for?

Epoetin alfa is a medication that works like erythropoietin – the body's natural hormone responsible for stimulating the production of red blood cells. It is used in the treatment of anemia, a condition whereby red blood cells are below normal range.

How should I take or use Epoetin Alfa?

Epoetin alfa is an injection with various dosing schedules, that may be given via the intravenous or subcutaneous route. Follow the dosing schedule instructed by your doctor.

However, subcutaneous epoetin alfa should NOT be used to treat anemia due to chronic kidney disease.

Do not shake the syringe vigorously.

What should I do if I forget to take or use Epoetin Alfa?

If you miss a dose of epoetin alfa, contact your doctor for further instructions on what to do.


Side Effects


What are some common side effects of Epoetin Alfa?

  • Flu-like syndrome e.g. fever, chills, headache, body aches
  • Usually occurs at the start of treatment. Maintain hydration – drink sufficient fluids – and take paracetamol if necessary.   
  • Nausea
  • Diarrhea
  • Increased blood pressure
  • Pain and redness at injection site
  • To reduce symptoms, alternate injection site and apply cold compress.

Inform your doctor is any of the following occurs:

  • Fever of 38°C or higher
  • Increased fatigue, weakness and pale skin colour
  • Severe headache, giddiness, light-headedness
  • Rapid heartbeat, sudden onset of chest pain or breathlessness
  • Signs of blood clot over a vein or calf tenderness
  • Seizures
  • Allergic reaction e.g. rash, itch, swelling, dizziness, breathing difficulty


Handling


How should I store Epoetin Alfa?

  • Keep away from children
  • Keep in a cool, dry place, away from direct sunlight
  • Store in the refrigerator. Do not freeze.

How do I throw away Epoetin Alfa safely?

Dispose the needle in a hard puncture-proof container. Do not attempt to re-cap the needle after use. Do not throw the exposed needle directly into the dustbin or leave it lying about.

How should I handle Epoetin Alfa safely?

Be careful to hold the syringe securely. Do not point the needle at anyone when uncapped.


For more information


What should I do if I overdose?

If you overdose on this medication, inform your doctor immediately.

Disclaimers

Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.

If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System, and SingHealth), community pharmacies (Guardian, Unity, and Watsons), and the Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.

Last Updated on February 2019



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