Cyclophosphamide (Oral)

Endoxan®


Uses


What is Cyclophosphamide (Oral) for?

Cyclophosphamide is an anticancer medicine used in the treatment of various types of cancers such as lymphomas and leukemias. 

How should I take or use Cyclophosphamide (Oral)?

Take the tablets during or immediately after meals. Drink plenty of fluids while taking this medicine. Follow the prescribed dosage. Do not cut or crush the tablet. To minimize the risk of bladder irritation, do not take at bedtime.

What should I do if I forget to take or use Cyclophosphamide (Oral)?

If you miss a dose, take it as soon as you remember. However, if it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Do not double dose.


Side Effects


What are some common side effects of Cyclophosphamide (Oral)?

  • Nausea, vomiting or appetite loss
  • Mouth sores or ulcers
  • Decrease in the white blood cells, red blood cells and platelets
    This increases your risk to infection. Avoid crowded areas and sick people. Wash your hands after using the toilet and before handling food.
  • Tiredness and lack of energy may occur
    If tiredness is a problem, do not drive a car or operate machinery. Avoid alcohol as it may make your feel more tired and drowsy.
  • Changes in the menstrual cycle for women

Inform your doctor if any of the following occurs:

  • Fever of 38°C or higher, chills or sore throat
  • Pain on urination
  • Redness, swelling or pain at the injection site
  • Unusual/unexplained bleeding, bruising or black tarry stools
  • Cough and shortness of breath
  • Joint pain and swelling of feet and lower legs
  • Hypersensitivity reactions like rashes, facial swelling, breathing difficulty

Handling


How should I store Cyclophosphamide (Oral)?

  • Keep away from children
  • Keep in a cool, dry place, away from direct sunlight
  • Store at room temperature

For more information


What should I do if I overdose?

If you overdose on this medicine, inform your doctor immediately.

Disclaimers

Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.

If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System, and SingHealth), community pharmacies (Guardian, Unity, and Watsons), and the Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.

Last Updated on October 2017



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