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Cyclophosphamide (Non-Cancer)

Drug Class: Commonly Known As: Category:
Adult

Cyclophosphamide (Non-Cancer) - Dosage and How to Use

How should Cyclophosphamide (Non-Cancer) be used?

Cyclophosphamide should be taken as prescribed by the doctor. It is usually given orally after food once in the morning, taken at the same time daily.

A typical adult dose ranges from 50 milligrams to 150 milligrams daily by mouth. For children, the dose is usually calculated based on body weight or body surface area. The dose varies for each person depending upon many factors such as how active your disease is and how you respond to or tolerate the medicine. Your doctor may reduce the dose if you have kidney or liver problem.

Drink plenty of water (preferably at least 8 glasses of water per day, unless otherwise advised by your doctor) while you are taking Cyclophosphamide to prevent this medicine from irritating your kidneys and bladder. Also, do not take the medicine at bedtime when the urine concentrate overnight to minimize the risk of irritation.

Cyclophosphamide tablets should be swallowed whole, with a glass of water. The tablets should not be crushed or chewed.

However, for people who are unable to swallow tablets whole, your pharmacist may advise you to soak the tablets in water for a few minutes before grinding them to minimise the inhalation of medicine powder. Talk to your pharmacist for further details if you have difficulty swallowing.

You may start to see improvement within a few weeks, but it may take several months to experience its full benefit.

What should I do if I miss a dose?

If you forget to take the tablet, take it as soon as you remember. If it is almost time for your next dose, skip the forgotten dose. Resume the next dose at the regular timing. Do not take a double dose to make up for a forgotten tablet.

If you forget your appointment and miss your injection, please make another appointment as soon as possible to arrange for next injection. Inform your doctor that you have missed your injection.

What should I do if I overdose?

  • Updated on Tuesday, October 24, 2017
  • Article contributed by Pharmacy Department, Autoimmunity & Rheumatology Centre (ARC), Rheumatology & Immunology KK Women's and Children's Hospital, Singapore General Hospital

The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

This leaflet answers some common questions about Cyclophosphamide. It does not contain all the available information. It also does not take the place of talking to your doctor or pharmacist.

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