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Clindamycin - What is it for

​Clindamycin is an antibiotic which works by preventing bacterial growth and multiplication. It is commonly used to treat infections involving the skin and soft tissues, bone and joints. It can also be applied on the skin to treat acne.

Clindamycin - Side Effects, Precautions, and Contraindications

What side effects can Clindamycin cause?

Common side effects include:

  • ​Diarrhoea
    • Drink plenty of water with oral rehydration salts to replenish your fluids and electrolytes.
    • If you experience any of the following severe symptoms, stop taking clindamycin and seek medical advice immediately:
        • Develop a fever or experience persistent diarrhoea, abdominal pain
        • Very watery or loose stools
        • Blood or pus in your stools
  • Nausea, vomiting, metallic or unpleasant taste in your mouth
    • Take clindamycin with or after food.
  • Heartburn, pain/burning sensation at the back of throat, stomach discomfort
    • Take clindamycin with a full glass of water. Take small but frequent meals, avoid spicy foods.

Very rarely, clindamycin may injure the liver. Stop this medication and seek medical advice immediately if you develop any of these symptoms:

  • Dark-coloured or tea-coloured urine
  • Light coloured stools
  • Severe abdominal pain, nausea and vomiting
  • Loss of appetite
  • Yellowing of the skin and eyes

The symptoms of a drug allergy include one or more of the following.

  • Swollen face/eyes/lips/tongue
  • Difficulty in breathing
  • Skin rashes over your whole body

If you experience any of these symptoms, you should stop your medicine immediately and see your doctor.

Before taking Clindamycin , what precautions must I follow?

​Inform your healthcare professional if:

  • You are allergic to clindamycin, lincomycin or any of the other ingredients of this medication.
  • You are pregnant, planning to become pregnant, or breastfeeding. Risks and benefits regarding the use of clindamycin should be discussed with your doctor.
  • You are taking any other medications, including supplements, traditional medications and herbal remedies.

What food or medicine must I avoid when I take Clindamycin ?

Clindamycin - Dosage and How to Use

How should Clindamycin be used?

​Oral Clindamycin

  • Clindamycin should be taken with or after food together with a full glass of water.
  • Complete the course of antibiotics as prescribed by your doctor. Incomplete treatment may cause the infection to recur.
  • Do check with your healthcare professional before stopping your medication.

Topical Clindamycin (Gel, Lotion)

  • Wash and dry your hands before and after using the medicine.
  • Clean and dry the area that you will be applying clindamycin on. Apply a thin layer of the medicine.
  • Topical clindamycin is usually applied 1 to 2 times a day. Follow your doctor's instructions.
  • Avoid your eyes, nose, mouth and lips when you apply clindamycin on your skin. Wash with water if the medicine gets into any of these areas. Avoid applying onto broken or irritated skin as it can worsen the skin condition.
  • It may take up to 3 months to see the effects of this medicine for acne. Do not stop using it even if you do not see results immediately.

What should I do if I miss a dose?

​If you forget to take a dose, take it as soon as you remember. If it is close to the time for your next dose, skip the missed dose and go back to your usual timing. Do not take two doses at the same time to make up for the missed dose.

What should I do if I overdose?

Clindamycin - Handling

How should I handle Clindamycin safely?

Clindamycin - Storage

How should I store Clindamycin ?

;#Keep away from children;#Keep in a cool, dry place, away from direct sunlight;#

How should I dispose of Clindamycin safely?

​Pack this medication into a black trash bag and seal it tightly before throwing into the rubbish chute or bin.

Clindamycin - Additional Information


  • Updated on 7/31/2021 12:00:00 AM
  • Article contributed by PSS National Medication Information Workgroup PSS National Medication Information Workgroup
The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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