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Bortezomib

Drug Class: Commonly Known As: Category:
Proteasome Inhibitor Velcade® Cancer-related

Bortezomib - What is it for

​Bortezomib is a chemotherapy that is used alone or in combination with other agents for the treatment of certain types of cancer.

Bortezomib - Side Effects, Precautions, and Contraindications

What side effects can Bortezomib cause?

Early side effects
  • Nausea and vomiting may occur
    There are medications available, which may prevent or decrease these side effects. If you are given these medications, take them as directed.
Delayed side effects
  • A drop in the blood cell counts may occur 7 to 14 days after treatment
  • Low blood pressure or dizziness
  • Diarrhea or constipation
  • Itch or rash
  • Muscle or joint pain, weakness
  • Tiredness
  • Mild swelling in the limbs
  • Numbness, tingling or burning sensation in the fingers and toes

Inform your doctor if any of the following occurs:

  • Fever of 38°C or higher
  • Excessive diarhea lasting longer than 24 hours
  • Unusual bleeding, bruising or black tarry stools
  • Confusion, loss of balance, vision disturbances, reduced strength or weakness in an arm/leg
  • Shortness of breath or chest pain

Before taking Bortezomib, what precautions must I follow?

What food or medicine must I avoid when I take Bortezomib?

  • Grapefruit juice, St John’s Wort, green tea or green tea extracts
  • Ascorbic acid (Vitamin C) supplements, especially 12 hours before and after bortezomib treatment

Bortezomib - Dosage and How to Use

How should Bortezomib be used?

What should I do if I miss a dose?

What should I do if I overdose?

Bortezomib - Handling and Storage

How should I handle Bortezomib safely?

How should I store Bortezomib?

How should I dispose of Bortezomib safely?

Bortezomib - Additional Information

  • Updated on Monday, May 6, 2019
  • Article contributed by Department of Pharmacy National Cancer Centre Singapore

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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