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Drug Class: Commonly Known As: Category:
Phosphodiesterase-3 Enzyme Inhibitor Agrylin Adult

Anagrelide - Side Effects, Precautions, and Contraindications

What side effects can Anagrelide cause?

  1. Headache
  2. Lethargy or generalised weakness
  3. Nausea, stomach pain, diarrhoea
  4. Dizziness
  5. Heart palpitations
  6. Fluid retention or leg swelling

Inform your doctor if any of the following occurs:

  1. Sign of an allergic reaction e.g. rash, itching, swollen, trouble breathing.
  2. Sign of bleeding e.g. throwing up blood, blood in the urine, black and tarry stools, bleeding from the gum, bruises without a reason or that get bigger.
  3. Severe headache or severe dizziness
  4. Chest pain or shortness of breath
  5. Irregular or fast heartbeat

Before taking Anagrelide , what precautions must I follow?

​Talk to your doctor before taking Anagrelide:

  1. If you have or think you might have a problem with your heart
  2. If you have ever had a long QT on ECG or other heartbeat that is not normal
  3. If you have any problems with your liver or kidneys
  4. If you are pregnant or planning to become pregnant
  5. If you are breast-feeding. Do not breast-feed while you take this drug and for 1 week after your last dose

There is an increased risk of bleeding when Anagrelide is taken together with aspirin. This risk is higher in patients with a platelet count of more than 1000 x 109/L.

Tell your doctor or pharmacist the medicines you are taking including vitamins and supplements. Some blood thinners, painkillers or antidepressants may increase the risk of bleeding while on Anagrelide.


What food or medicine must I avoid when I take Anagrelide ?

Anagrelide - Additional Information

  • Updated on 6/12/2019 12:00:00 AM
  • Article contributed by Pharmacy Singapore General Hospital
The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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