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Aflibercept

Drug Class: Commonly Known As: Category:
Zaltrap® Cancer-related

Aflibercept - What is it for

Aflibercept blocks the growth of blood vessels that supply oxygen and nutrients to cancer cells. It is used in combination with chemotherapy for the treatment of colorectal cancer.

Aflibercept - Side Effects, Precautions, and Contraindications

What side effects can Aflibercept cause?

  • Increased blood pressure that may cause headache or vision problems
  • Protein loss in urine
  • Diarrhea or mild abdominal pain
  • If you are receiving this together with chemotherapy, the chances of having low blood counts may increase slightly.
   Please seek medical attention if any of the following occurs:
  • Unusual bleeding problems such as nosebleed, coughing blood, blood in vomit or stools
  • Signs of blood clot e.g. painful leg swelling, sudden breathlessness, chest pain or stroke symptoms
  • Wounds that do not heal or are slow to heal
  • Sudden severe abdominal pain accompanied with fever, constipation, nausea or vomiting
  • Fever of 38° C or higher
  • Severe diarrhea (more than 4 episodes a day) and dehydration

Before taking Aflibercept, what precautions must I follow?

  • Notify your doctor at least 4 weeks before going for any surgical procedures e.g. biopsy, tooth extraction etc. as Aflibercept may need to be temporarily withheld.

What food or medicine must I avoid when I take Aflibercept?

Aflibercept - Dosage and How to Use

How should Aflibercept be used?

What should I do if I miss a dose?

What should I do if I overdose?

Aflibercept - Handling and Storage

How should I handle Aflibercept safely?

How should I store Aflibercept?

How should I dispose of Aflibercept safely?

Aflibercept - Additional Information

  • Updated on Friday, August 17, 2018
  • Article contributed by Department of Pharmacy National Cancer Centre Singapore

    The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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