• Diarrhea (may occur initially)
• Decreased appetite
• Mouth sores
• Acne, rash, dry skin, itching, skin redness
  Avoid excessive exposure to sunlight as it may worsen the rash or acne, or cause sunburn.​ Use sunscreen and covered clothing if you need to be un​​​der the sun.
• Nail infection

Inform your doctor if any of the following occurs:

• Diarrhea more than 4 times a day and not controlled by anti-diarrheal medicines
• Severe skin peeling or blistering
• Yellowing of the eyes of skin, tea-colored urine, severe right-sided stomach ache or unusual bruising
• Rapid or abnormal heartbeat, unusual tiredness, swelling of the hands and feet, or sudden weight gain
• Severe eye discomfort, sensitivity to light, blurred vision
• Fever, severe cough and shortness of breath

• Inform your doctor or pharmacist if you:
• Have any other medical conditions
• Are taking any long-term medicines or supplements
• Have any history of eye problems or are using contact lenses
• Use effective birth control during treatment and for at least 2 weeks after stopping treatment. Inform your doctor if you or your partner suspect or plan to get pregnant.

​It should be taken on an empty stomach, either 1 hour before or 3 hours after food. Take it around the same time each day.

If you miss a dose of Afatinib, you can take it as soon as you remember if there is at least 8 hours before the next dose. However, if there is less than 8 hours before the next dose, skip the dose and take the next dose at the usual time. Do not double dose.

​If you overdose on this medicine, inform your doctor immediately.

​Do not break or crush the tablet.