Afatinib

What is Afatinib for?

Afatinib is a targeted medicine used in the treatment of Non-Small Cell Lung Cancer with EGFR mutation.

How should I take or use Afatinib?

It should be taken on an empty stomach, either 1 hour before or 3 hours after food. Take it around the same time each day.

What should I do if I forget to take or use Afatinib?

If you miss a dose of Afatinib, you can take it as soon as you remember if there is at least 8 hours before the next dose. However, if there is less than 8 hours before the next dose, skip the dose and take the next dose at the usual time. Do not double dose.

What precautions should I take when taking or using Afatinib?

• Inform your doctor or pharmacist if you:
• Have any other medical conditions
• Are taking any long-term medicines or supplements
• Have any history of eye problems or are using contact lenses
• Use effective birth control during treatment and for at least 2 weeks after stopping treatment. Inform your doctor if you or your partner suspect or plan to get pregnant.

What are some common side effects of Afatinib?

• Diarrhea (may occur initially)
• Decreased appetite
• Mouth sores
• Acne, rash, dry skin, itching, skin redness
  Avoid excessive exposure to sunlight as it may worsen the rash or acne, or cause sunburn. Use sunscreen and covered clothing if you need to be under the sun.
• Nail infection

Inform your doctor if any of the following occurs:

• Diarrhea more than 4 times a day and not controlled by anti-diarrheal medicines
• Severe skin peeling or blistering
• Yellowing of the eyes of skin, tea-colored urine, severe right-sided stomach ache or unusual bruising
• Rapid or abnormal heartbeat, unusual tiredness, swelling of the hands and feet, or sudden weight gain
• Severe eye discomfort, sensitivity to light, blurred vision
• Fever, severe cough and shortness of breath

How should I store Afatinib?

• Keep away from children
• Keep in a cool, dry place, away from direct sunlight
• Store at room temperature

How should I handle Afatinib safely?

Do not break or crush the tablet.

What should I do if I overdose?

If you overdose on this medicine, inform your doctor immediately.