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Gout: What is it, Causes, Symptoms, Risk Factors, Diagnosis, Treatment Options | Singapore General Hospital

Gout - How to prevent?

Gout - Causes and Risk Factors

What causes Gout?

Gout is the result of deposits of needle like crystals of uric acid in the joint spaces. Uric acid, a substance that results from the breakdown of purines in the body, usually dissolves in the blood and passes through the kidneys into the urine. In people with gout, the uric acid level in the blood becomes elevated.

This is called hyperuricaemia and can be due either to the increased production of uric acid eg. due to consumption of food rich in purines or decreased excretion of uric acid from the kidney eg. renal impairment.

Risk factors of Gout

  • Hyperuricaemia - Most people with gout have hyperuricaemia although not all people with hyperuricaemia have gout
  • Overweight - Excessive food intake increases the body’s production of uric acid
  • Excessive use of alcohol - Alcohol interferes with the excretion of uric acid from the body
  • Food with high purine content
  • Use of certain medications such as diuretics, salicylates, cyclosporine, niacin, levodopa
  • Start of a uric-acid lowering treatment
  • Crash diet
  • Joint trauma
  • Surgery or sudden, severe illness
  • Genes

Gout - Preparing for surgery

Gout - Post-surgery care

Gout - Other Information

The information provided is not intended as medical advice. Terms of use. Information provided by SingHealth

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