Oxaliplatin


Uses


What is Oxaliplatin for?

Oxaliplatin is an intravenous chemotherapy used alone or in combination with other agents for the treatment of certain types of cancer.


Side Effects


What are some common side effects of Oxaliplatin?

Early side effects

  • Tingling sensations experienced as “pins and needles” in the fingers or feet.
  • Sensations of cramps or altered sensitivity around the mouth or throat which may be triggered by cold environment or taking cold food or beverages.
    To prevent or reduce the severity of the condition, avoid the cold and keep yourself warm by covering with a blanket, wearing a sweater and/or taking hot beverages. Your attending nurse may also slow down the infusion.
  • Nausea and vomiting may occur for 24 to 48 hours after treatment.
    There are medications available which may prevent or decrease these side effects. If you are given these medications, take them as directed.

Delayed side effects

  • A drop in the blood cell counts may occur several days after treatment.
  • Abnormal sensation, such as numbness, tingling, or burning sensation may be experienced in the hands or feet. 
  • Minimal hair loss may occur.

Inform your doctor if any of the following occurs:

  • Fever of 38°C or higher.
  • Impairment of sense or experience of abnormal sensation in the limbs which persists several days after administration of the drug.
  • Unusual bleeding, bruising or black tarry stools.

Disclaimers

Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.

If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System, and SingHealth), community pharmacies (Guardian, Unity, and Watsons), and the Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.

Last Updated on October 2017



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