Ibrutinib

What is Ibrutinib for?

Ibrutinib is a targeted medication used to treat chronic lymphocytic leukemia, Waldenström’s macroglobulinemia and mantle cell lymphoma.

How should I take or use Ibrutinib?

 It is a capsule, taken by mouth once daily and swallowed whole with water. Take at around the same time each day, with or without food. Take the exact number of capsules instructed by your doctor.

What should I do if I forget to take or use Ibrutinib?

If you miss a dose of Ibrutinib, take it as soon as you can on the same day and return to your usual dosing time the next day. Do not double dose to make up for a missed dose.  

What precautions should I take when taking or using Ibrutinib?

• Inform your doctor or pharmacist if you:
• Have any other medical conditions e.g. heart problems, liver problems.
• Are taking any other medication or supplements e.g. warfarin, fish oil or vitamin E.
• Use effective birth control during treatment and for 3 months after stopping Ibrutinib. Inform your doctor if you or your partner plan for or suspect pregnancy.

What food or medication should I avoid when I take or use Ibrutinib?

Avoid taking grapefruit and its juice while you are on Ibrutinib.

What are some common side effects of Ibrutinib?

• Nausea and vomiting
• Diarrhea and/or stomach pain
• Decreased appetite
• Tiredness and lack of energy
• Bone pain or muscle ache
• Mild swelling of the hands or feet
• Skin rash
• Increased risk of bruising or bleeding
  Inform your doctor if you had a recent surgery or if any surgery is planned for you.
• Increased risk of infections
  To minimise risk, avoid crowds or being near people with infection.

Inform your doctor if any of the following occurs:

• Rapid heartbeat, chest discomfort or shortness of breath
• Unusual light-headedness, giddiness or weakness
• Signs of infection – fever of of 38°C or higher, chills, cough, sore throat, pain or difficulty urinating
• Unusual bruising, bleeding or black sticky stools
• Severe diarrhea
• Severe muscle pain or weakness

How should I store Ibrutinib?

• Keep away from children
• Keep in a cool, dry place, away from direct sunlight
• Store at room temperature

How should I handle Ibrutinib safely?

Do not chew, open or break the capsule.

What should I do if I overdose?

If you overdose on this medication, inform your doctor immediately.