Filgrastim

Neupogen®, Nivestim®


Uses


What is Filgrastim for?

Filgrastim is a medicine which stimulates the bone marrow to produce white blood cells. White blood cells help your body to fight infections.

How should I take or use Filgrastim?

It is a subcutaneous injection with various dosing schedule. Follow the dosage schedule accordingly and give at least 24 hours before or after chemotherapy. Filgrastim is preferably given at the same time for every dose.

  • Do not shake the syringe.
  • Take the syringe out of the refrigerator 30 minutes before use and allow it to reach room temperature before injecting.
  • Check the syringe for any particulate matter or discolouration before injecting. Do not use the injection if these are present.

What should I do if I forget to take or use Filgrastim?

If you miss a dose of Filgrastim, inject it as soon as you can if it is within 12 hours of the missed dose. If it is over 12 hours since your missed dose, skip the missed dose and go back to your usual dosing schedule. Do not inject twice within the same day.


Side Effects


What are some common side effects of Filgrastim?

  • Mild to moderate bone pain may occur
  • This may be relieved by taking paracetamol.
  • Flu-like syndrome e.g. fever, chills, headache, body aches
  • Usually occurs at start of treatment. Maintain hydration – drink lots of fluids – and take paracetamol if necessary.
  • Headache
  • Mild skin rash may occur
  • More common in patients with history of sensitive skin.
  • Pain and redness at injection site

Inform your doctor if any of the following occurs:

  • Fever of 38°C or higher
  • Sores in the mouth and throat
  • Chest pain and rapid irregular heartbeat
  • Abnormal severe abdominal or shoulder pain
  • Allergic reaction e.g. rash, itch, swelling, dizziness and breathing problems

Handling


How should I store Filgrastim?

  • Keep away from children
  • Keep in a cool, dry place, away from direct sunlight
  • Store in the refrigerator. Do not freeze.
  • Discard any syringes exposed to room temperature (up to 30°C) for a period longer than 6 hours.

How do I throw away Filgrastim safely?

Dispose the needle in a hard, puncture-proof container. Do not attempt to re-cap the needle after use. Do not throw the exposed needle directly into the dustbin or leave it lying about.

How should I handle Filgrastim safely?

Be careful to hold the syringe securely. Do not point the needle at anyone when uncapped.


For more information


What should I do if I overdose?

If you overdose on this medicine, inform your doctor immediately.

Disclaimers

Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.

If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.

This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System, and SingHealth), community pharmacies (Guardian, Unity, and Watsons), and the Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.

Last Updated on October 2017



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