Evolocumab is a type of monoclonal antibody (a man-made protein that attaches to a target in the body) that increases the liver’s ability to remove bad cholesterol. This lowers the amount of ‘bad cholesterol’ in the blood.
High ‘bad cholesterol’ levels can cause blood vessels to clog up and lead to chest pain (angina), heart attack or stroke. By reducing the amount of bad cholesterol in the body, this medication reduces the risk of future heart attack and stroke.
This medication may also be used for patients with high ‘bad cholesterol’ levels in their blood because of a hereditary condition (a medical condition that runs in the family).
Before using the pre-filled injection pen,
Using the pre-filled injector pen,
Inform your healthcare professional if:
The symptoms of a drug allergy include one or more of the following:
If you experience any of these symptoms, you should stop your medication and see your healthcare professional immediately.
Store in the refrigerator between 2-8°C. Do not freeze or shake.
If needed, you may store this medication at room temperature (in a cool dry place away from sunlight) for up to 30 days. If stored at room temperature and not used within 30 days, throw this medication away.
If used at home, you may throw this injection away along with the used needles, into a metal tin, glass jar or thick plastic container (e.g. detergent bottles) to prevent any needlestick injury.
Disclaimers
Please take note that the above is not a complete list of all possible side effects. If you have any concerns about your medication or if you have other side effects that you think are caused by this medication, please consult your doctor or pharmacist.
If you take more than the recommended dose, please seek medical advice immediately. The information provided on this page does not replace information from your healthcare professional. Please consult your healthcare professional for more information.
This article is jointly developed by members of the National Medication Information workgroup. The workgroup consists of cluster partners (National Healthcare Group, National University Health System and SingHealth), community pharmacies (Guardian, Unity and Watsons) and Pharmaceutical Society of Singapore. The content does not reflect drug availability and supply information in pharmacies and healthcare institutions. You are advised to check with the respective institutions for such information.
Last updated on February 2025
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