Administration leaflet: Dissolving Sachets

1. If you are directed to use half a sachet, remember to flatten the sachet first to ensure that the medicine is evenly distributed.

2. Fold the sachet into half.

3. Tear or cut the top of the sachet.

4. Pour approximately half the content or the whole content, depending on the dose indicated on the medication label, into a cup.

5. Add water into the cup.

Water should be boiled and cooled down to room temperature.

• Acetylcysteine granules
  • Use a small quantity of water
• Sodium zirconium cyclosilicate granules
  • Use approximately 45mL of water
• Cholestyramine, Ispaghula husk, Fosfomycin, urinary alkalizer powders (e.g. Ural®)
  • Use a full cup of water (approximately 200-250mL)
• Macrogol 4000
  • Use a full cup of water (approximately 200-250mL) for one sachet or half cup of water for half a sachet.
  • You may also use other beverages such as fruit juices or milk for dissolving Macrogol powder, but do not use soda as it may cause stomach discomfort in some patients.

6. Stir to dissolve/disperse the powder.

(make sure you stir the powder again if the powder settles before drinking)

7. Drink the entire solution in the cup.

You may use a syringe to administer the solution to younger children, if needed.