Clin Asst Prof Anthony Yii Chau Ang

Clin Asst Prof Anthony Yii is a Senior Consultant with the Department of Respiratory & Critical Care Medicine at Changi General Hospital (CGH). Dr Yii obtained his medical degree from the University of Cambridge and was accredited as a specialist in Respiratory Medicine in 2017. He specialises in the management of respiratory conditions and holds a Master of Public Health from Johns Hopkins University, focusing on Epidemiology and Biostatistics.

Dr Yii serves as the clinical lead for value-driven care and quality improvement initiatives for chronic obstructive pulmonary disease (COPD) at both the hospital and healthcare cluster levels. In this role, he leads initiatives to optimise care delivery, enhance patient outcomes, and improve cost-effectiveness in respiratory care. He is also a member of the Pharmacy and Therapeutics committee, and SingHealth Centralised Institutional Review Board (CIRB).

Dr Yii’s research primarily focuses on asthma, COPD, and airway diseases, reflecting his dedication to advancing evidence-based approaches to healthcare quality and population health. His contributions to the field have been recognised at platforms such as the SingHealth Publish! Award and the Johns Hopkins Master of Public Health Capstone Award for Outstanding Achievement.

• Master of Public Health, United States, 2024
• Specialist Accreditation Board (Respiratory Medicine), 2017
• MRCP(UK), 2013
• MB BChir, United Kingdom, 2009

• Strategy Lead (Chronic Obstructive Pulmonary Disease), SingHealth Value Council, 2024 – Present
• Member, Pharmacy and Therapeutics Committee, Changi General Hospital, 2023 – Present
• Board C Member, SingHealth Centralised Institutional Review Board (CIRB), 2022 – Present
• Clinical Champion, Chronic Obstructive Pulmonary Disease Value-Based Healthcare Programme, Changi General Hospital, 2021 – Present
• Member, General Medicine Clinical Quality and Quality Improvement Committee, 2022 – 2024

• Outstanding Author, Journal of Thoracic Disease, 2024
• Master of Public Health Capstone Award for Outstanding Achievement, Johns Hopkins Bloomberg School of Public Health, 2024
• The Commendation Medal (COVID-19), Prime Minister's Office Singapore, 2023
• Star Award, Singapore Health Quality Service Awards, 2022
• Hero Award, Singapore Health Quality Service Awards, 2021

• Asthma
• COPD
• Lung cancer

• Saripalli KR, Sieow N, Chan YH, Chan W, Choo XN, Yii A, Tay TR. Treatable traits in an Asian difficult asthma cohort. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2024.
• Alsuwaigh R, Yii A, Loh CH, Xu X, Bahety P, Navarro Rojas AA, Milea D, Tee A. A comparison of GOLD 2019 and 2023 recommendations to contemporaneous real-world inhaler treatment patterns for chronic obstructive pulmonary disease management in Singapore. J Thorac Dis 2024; 16: 847-861.
• Yii A, Xu X, Loh CH, Bahety P, Navarro Rojas AA, Milea D, Tee A. Year-to-year trajectories of hospital utilisation rates among patients with COPD: a real-world, single-centre, retrospective cohort study. BMJ Open 2023; 13: e072571.
• Tay TR, Yii A, Chan YH, Choo XN. Interval change in fractional exhaled nitric oxide (FENO) reflects short-term change in adherence following electronic inhaler reminders. Journal of Asthma 2023; 60: 1613-1621.
• Alsuwaigh R, Cao Y, Puan Y, Yii A, Mohamed Noor SB, Ye H, Chen H, Li XL, Binte Mohd Noor N, Liew J, Tay TR. Nebulizer versus metered dose inhaler with space chamber (MDI spacer) for acute asthma and chronic obstructive pulmonary disease exacerbation: attitudes of patients and healthcare providers in the COVID-19 era. Journal of Asthma 2023; 60: 600-608.
• Khoo SSH, Yii ACA. More Than Asthma: A Case Report of Eosinophilic Bronchiolitis. Proceedings of Singapore Healthcare 2022; 31: 20101058221103371.
• Sim M, Yii A, Xu X, Bahety P, Loh CH, Navarro Rojas AA, Milea D, Tee A. Characteristics of Patients with Chronic Obstructive Pulmonary Disease Treated with Long-Acting Bronchodilators in a Real-World Setting in Singapore: A Single-Center Observational Study. Int J Chron Obstruct Pulmon Dis 2022; 17: 1349-1363.
• Fong I, Low TB, Yii A. Characterisation of the post-tuberculous phenotype of bronchiectasis: A real-world observational study. Chronic Respiratory Disease 2022; 19: 14799731221098714.
• Rosario BH, Shafi H, Yii ACA, Tee LY, Ang ASH, Png GK, Ang WST, Lee YQ, Tan PT, Sahu A, Zhou LF, Zheng YL, Slamat RB, Taha AAM. Evaluation of multi-component interventions for prevention of nosocomial pneumonia in older adults: a randomized, controlled trial. European Geriatric Medicine 2021; 12: 1045-1055.
• Saripalli KR, Tan CS, Yii A. A lung mass: Not the usual suspect, but not above suspicion. Respiratory medicine case reports 2021; 33: 101389.
• Yii ACA, Tay T-R, Puah SH, Lim H-F, Li A, Lau P, Tan R, Neo L-P, Chung KF, Koh MS. Blood eosinophil count correlates with severity of respiratory failure in life-threatening asthma and predicts risk of subsequent exacerbations. Clinical & Experimental Allergy 2019; 49: 1578-1586.
• Yii ACA, Loh CH, Tiew PY, Xu H, Taha AAM, Koh J, Tan J, Lapperre TS, Anzueto A, Tee AKH. A clinical prediction model for hospitalized COPD exacerbations based on "treatable traits". Int J Chron Obstruct Pulmon Dis 2019; 14: 719-728.
• Yii AC, Soh AZ, Chee CBE, Wang YT, Yuan J-M, Koh W-P. Asthma, Sinonasal Disease, and the Risk of Active Tuberculosis. The Journal of Allergy and Clinical Immunology: In Practice 2019; 7: 641-648.e641.
• Tay TR, Choo XN, Yii A, Chung KF, Chan YH, Wong HS, Chan A, Tee A, Koh MS. Asthma phenotypes in a multi-ethnic Asian cohort. Respiratory Medicine 2019; 157: 42-48.
• Yii ACA, Tay TR, Choo XN, Koh MSY, Tee AKH, Wang DY. Precision medicine in united airways disease: A "treatable traits" approach. Allergy 2018; 73: 1964-1978.
• Foong NZE, Yii ACA, Hsu AAL. Severe life-threatening asthma precipitated by a topical nonsteroidal anti-inflammatory drug. Annals of Allergy, Asthma & Immunology 2018; 120: 535-536.
• Yii ACA, Tan JHY, Lapperre TS, Chan AKW, Low SY, Ong TH, Tan KL, Chotirmall SH, Sterk PJ, Koh MS. Long-term future risk of severe exacerbations: Distinct 5-year trajectories of problematic asthma. Allergy 2017.
• Nguyen HV, Bose S, Mital S, Yii AC, Ang SY, Lam SS, Anantham D, Finkelstein E, Koh MS. Is bronchial thermoplasty cost-effective as treatment for problematic asthma patients? Singapore's perspective on a global model. Respirology 2017.
• Ma TT, Zhuang Y, Gong HY, Yii AC, Wang XY, Shi HZ. Predictive value of respiratory symptoms for the diagnosis of pollen-induced seasonal asthma among children and adults in Inner Mongolia. Ther Clin Risk Manag 2017; 13: 967-974.
• Goh KJ, Yii ACA, Lapperre TS, Chan AK, Chew FT, Chotirmall SH, Koh MS. Sensitization to Aspergillus species is associated with frequent exacerbations in severe asthma. Journal of asthma and allergy 2017; 10: 131-140.
• Koh MS, Yii AC, Ong YY. Asthma in Singapore: Past, Present and Future. Annals of the Academy of Medicine, Singapore 2017; 46: 81-83.
• Yii AC, Koh MS, Lapperre TS, Tan GL, Chotirmall SH. The emergence of Aspergillus species in chronic respiratory disease. Frontiers in bioscience 2017; 9: 127-138.
• Poh TY, Mac Aogain M, Chan AK, Yii AC, Yong VF, Tiew PY, Koh MS, Chotirmall SH. Understanding COPD-overlap syndromes. Expert review of respiratory medicine 2017; 11: 285-298.
• Aw DK, Tan MZ, Yii AC, Ng DH. Unusual complication of bronchoscopy. Respiratory medicine case reports 2016; 19: 173-176.
• Norgett EE, Yii A, Blake-Palmer KG, Sharifian M, Allen LE, Najafi A, Kariminejad A, Karet Frankl FE. A role for VAX2 in correct retinal function revealed by a novel genomic deletion at 2p13.3 causing distal Renal Tubular Acidosis: case report. BMC medical genetics 2015; 16: 38.
• Yii AC, Tan GL, Tan KL, Lapperre TS, Koh MS. Fixed airways obstruction among patients with severe asthma: findings from the Singapore General Hospital-Severe Asthma Phenotype Study. BMC pulmonary medicine 2014; 14: 191.
• Yii AC, Koh MS. A review of psychological dysfunction in asthma: affective, behavioral and cognitive factors. The Journal of asthma : official journal of the Association for the Care of Asthma 2013; 50: 915-921.