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Clin Assoc Prof Rahat Husain

​MBBS, FRCOphth, MD(Res), FAMS

Senior Consultant

Singapore National Eye Centre Singapore National Eye Centre

Specialty: Ophthalmology

Conditions Treated By This Doctor

Clinical Interests

Cataract & Comprehensive Ophthalmology, Glaucoma

Clinical Appointments

Academic Appointments

Deputy Vice-Chair, Regional / Community Eye Care, Ophthalmology and Visual Sciences Academic Clinical Programme (EYE ACP)

Ophthalmology & Visual Sciences Academic Clinical Programme

About Doctor

Clinical Associate Professor Husain is the current Director of Regional and Community Eye Care for SingHealth, as well as being a Senior Consultant at Singapore National Eye Centre (Glaucoma Department) and Changi General Hospital. He was the previous Head of the Eye Service at CGH. He qualified from University College London Medical School and completed basic surgical training in the south of England. From 2002 to 2004 he was employed by the Institute of Ophthalmology (London) as a Clinical Research Fellow at Singapore National Eye Centre where he ran the Singapore 5-Fluorouracil Trabeculectomy Study. This large study examined the natural history of glaucoma surgery, and, in particular, examined the effects of an anti-scarring agent on surgical outcomes. He was also involved in other research projects in patients with primary angle closure glaucoma, namely the Angle Closure Natural History Study and the ACLIPS study. Whilst in Singapore, he also took part in several epidemiological surveys in Indonesia to describe the prevalence and causes of low vision and cataract in that group of people. He returned to England to complete his higher surgical training and went on the gain specialist fellowship training in glaucoma at St Thomas’ and Kings College Hospitals, London.

Clinical Associate Professor Husain has published numerous articles and given many presentations, mainly on the subject of glaucoma and recently has focused on the interaction between glaucoma surgery and cataract surgery.

Languages Spoken

  • English

Education and Training

  • FAMS (2018)
  • MD(Res) (2010)
  • FRCOphth (2009)
  • MBBS (1995)

Professional Appointments and Committee Memberships

  • Institution Sustainability Officer (ISO) (2026)
  • Member, Education Research Working Committee, Singapore National Eye Centre (2018)
  • Senior Clinical Lecturer, Yong Loo Lin School of Medicine, National University of Singapore (2016 – Present)
  • Member, Outpatient Committee, Singapore National Eye Centre (2015 – Present)
  • Associate Program Director, Ophthalmology Residency Programme, SingHealth (2014 – 2018)
  • Member, Medical Audit Committee, Changi General Hospital (2014 – 2017)
  • Member, Quality Assurance Committee, Singapore National Eye Centre (2013 – Present)​

Awards

  • Most Passionate Educator, Residency in SingHealth Excels (RiSE) Award (2012)
  • Gold Award, Singapore Health Quality Service Award, SingHealth (2012, 2011)
  • Best Paper Award, Glaucoma Section, American Academy of Ophthalmology (AAO) Meeting (2010)
  • Silver Award, Singapore Health Quality Service Award, SingHealth (2010, 2009)
  • Best Presentation Award, Southern Ophthalmology Society, UK (2009)

Research Trials/Clinical Trials

  • Prospective Comparative Study of IMOvifa, Melbourne Rapid Fields (MRF) Test and Humphrey Field Analyzer Perimetry in Patients with Glaucoma (2026 – Present)
  • Targeting Metabolic Insufficiency (TAMING) Glaucoma Study: A 2-year Multi-centre, Double-masked, Randomised, Placebo-controlled Trial of Nicotinamide (Vitamin B3) Supplementation in Glaucoma (2024 – Present)
  • The Water Drinking Test in Eyes Undergoing Phacoemulsification with Trabecular Micro-bypass Stent (iStent): A Single-arm Prospective Study (2023 – Present)
  • Tackling Extreme Fibrosis Following Glaucoma Surgery (2023 – Present)
  • Eagle Device for Non-contact Trabeculoplasty in Angle Closure (ENTRAC) (2023 – Present)
  • Artificial Intelligence Based Gatekeeping for Glaucoma Clinics (2022 – Present)
  • Fibrosis in Glaucoma Surgery Study (FiGS) (2022 – Present)
  • Direct Selective Laser Trabeculoplasty for Primary Open Angle Glaucoma and Ocular Hypertension and Normal Tension Glaucoma in Ethnic Chinese Population (2022 – Present)
  • The Asia Primary Tube versus Trab (TVT) Study (2016 – Present)
  • The Glaucoma Initial Treatment Study: Comparing the Effectiveness of Selective Laser Trabeculoplasty with Topical Medication. A Multi-Centre, Prospective and Randomized Controlled Clinical Trial (2015 – Present)
  • Development of a Novel Test (SCoPE : Singapore Colour Pupillometry Evaluation) for Assessing Photoreceptor Dysfunction in Patients with Glaucoma Using the Pupillary Light Reflex (2013 – Present)
  • Investigating the Genetic Basis of Glaucoma (2011 – Present)

Publications

  1. Husain R, Li W, Gazzard G, Foster P, Chew P, Oen F, Phillips R, Khaw P, Seah S, Aung T. Longitudinal Changes in Anterior Chamber Depth and Axial Length in Asian Subjects After Trabeculectomy Surgery. Br J Ophthalmol. 2013 Jul;97(7):852-6.
  2. Nongpiur ME, Foo V, De Leon JM, Baskaran M, Tun TA, Husain R, Perera SA, Aung T. Evaluation of Choroidal Thickness, Intraocular Pressure and Serum Osmolality After the Water Drinking Test in Eyes with Primary Angle-closure. Invest Ophthalmol Vis Sci. 2015 Mar 5. pii: IOVS-14-15280. doi: 10.1167/iovs.14-15280.
  3. Aung T et al. A Common Variant Mapping to CACNA1A is Associated with Susceptibility to Exfoliation Syndrome. Nat Genet. 2015 Feb 23. doi: 10.1038/ng.3226.
  4. Girard MJ, Tun TA, Husain R, Acharyya S, Haaland BA, Wei X, Mari JM, Perera SA, Baskaran M, Aung T, Strouthidis NG. Lamina Cribrosa Visibility Using Optical Coherence Tomography: Comparison of Devices and Effects of Image Enhancement Techniques. Invest Ophthalmol Vis Sci. 2015 Jan 15;56(2):865-74.
  5. Tun TA, Baskaran M, Perera SA, Htoon HM, Aung T, Husain R. Swept-source Optical Coherence Tomography Assessment of Iris-trabecular Contact after Phacoemulsification with or without Goniosynechialysis in Eyes with Primary Angle Closure Glaucoma. Br J Ophthalmol. 2015 Jan 8. pii: bjophthalmol-2014-306223.
  6. Trikha S, Perera SA, Husain R, Aung T. The Role of Lens Extraction in the Current Management of Primary Angle-closure Glaucoma. Curr Opin Ophthalmol. 2015 Mar;26(2):128-34.
  7. Li Z et al. A Common Variant Near TGFBR3 is Associated with Primary Open Angle Glaucoma. Hum Mol Genet. 2015 Jul 1;24(13):3880-92.
  8. Nongpiur ME et al. Evaluation of Primary Angle-closure Glaucoma Susceptibility Loci in Patients with Early Stages of Angle-closure Disease. Ophthalmology. 2018 Jan 5. pii: S0161-6420(17)31588-9.
  9. Chiam N, Baskaran M, Li Z, Perera S, Goh D, Husain R, Khor CC, Cheng CY, Aung T, Vithana EN. Social, Health and Ocular Factors Associated with Primary Open-angle Glaucoma Amongst Chinese Singaporeans. Clin Exp Ophthalmol. 2017 Jun 16.
  10. Aung T et al. Genetic Association Study of Exfoliation Syndrome Identifies A Protective Rare Variant at LOXL1 and Five New Susceptibility Loci. Nat Genet. 2017 Jul;49(7):993-1004.
  11. Rodrigues IA, Alaghband P, Beltran Agullo L, Galvis E, Jones S, Husain R, Lim KS. Aqueous Outflow Facility After Phacoemulsification with or without Goniosynechialysis In Primary Angle Closure: A Randomised Controlled Study. Br J Ophthalmol. 2017 Jul;101(7):879-885.
  12. Verma S, Nongpiur ME, Atalay E, Wei X, Husain R, Goh D, Perera SA, Aung T. Visual Field Progression in Patients with Primary Angle-closure Glaucoma Using Pointwise Linear Regression Analysis. Ophthalmology. 2017 Jul;124(7):1065-1071.
  13. Tun TA, Tan SS, Atalay E, Verma S, Nongpiur ME, Baskaran M, Aung T, Husain R. Investigation of the Variability of Anterior Chamber Scan Protocol with Cirrus High Definition Optical Coherence Tomography. Exp Ophthalmol. 2017 Jul;45(5):464-471.
  14. Tun TA, Baskaran M, Tan SS, Perera SA, Aung T, Husain R. Evaluation of the Anterior Segment Angle-to-angle Scan of Cirrus High-definition Optical Coherence Tomography and Comparison with Gonioscopy and with the Visante OCT. Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):59-64.
  15. Atalay E, Nongpiur ME, Yap SC, Wong TT, Goh D, Husain R, Perera SA, Aung T. Pattern of Visual Field Loss in Primary Angle-closure Glaucoma Across Different Severity Levels. Ophthalmology. 2016 Sep;123(9):1957-64.
  16. Khor CC et al. Genome-wide Association Study Identifies Five New Susceptibility Loci for Primary Angle Closure Glaucoma. Nat Genet. 2016 May;48(5):556-62.
  17. Clarke J, Sangermani C, Husain R, Khaw P. Glaucoma: Surgical Treatments and Anti-scarring Strategies. Postgraduate Doctor Journal. August 2003.
  18. Husain R, Clarke JC, Seah SK, Khaw PT. A Review of Trabeculectomy in East Asian People – The Influence of Race. Eye. 2005 89(3):288-90.
  19. Husain R. The Management of Patients with Cataracts and Medically Uncontrolled Glaucoma. Med Hypothesis Discov Innov Ophthalmol. 2014 Spring;3(1):20-30. Review.
  20. Hernstadt DJ, Husain R. Effect of Prostaglandin Analogue Use on the Development of Cystoid Macular Edema After Phacoemulsification Using STROBE Statement Methodology. J Cataract Refract Surg. 2017 Apr;43(4):564-569.