Clin Assoc Prof Tan Wei Chieh Jack

Clinical Associate Professor Jack Tan is the Deputy Chief Executive Officer (Cluster Cardiac Care Network) and Senior Consultant, Department of Cardiology at the National Heart Centre Singapore. He was the Head of Department of Cardiology at NHCS from 2022 to May 2023. He was also the Head, Department of Cardiology at NHCS@SKH (Sengkang General Hospital) from 2015 to 2021.

Clin Assoc Prof Tan's sub-specialty is interventional cardiology. He is also in the Clinical EXCO of the SingHealth Duke-NUS Cardiovascular Sciences Academic Clinical Programme.

• FESC, 2015
  
• FACC, 2014
  
• FAMS (Intensive Care), Singapore AMS, 2014
  
• Singapore Management University, Executive MBA (Dean’s List), 2013
  
• FAMS (Cardiology), Singapore AMS, 2006
  
• ACMS, USA American College of Sports Medicine
  
• Master of Medicine (Internal Medicine), National University of Singapore (NUS), 2002
  
• Royal College of Physicians (UK) Diploma, 2002
• Bachelor of Medicine and Surgery, NUS, 1997
  
  

• Deputy Chief Executive Officer (Cluster Cardiac Care Network), National Heart Centre Singapore, 1 June to Present
• Head, Department of Cardiology, National Heart Centre Singapore, Jan 2022 to May 2023 
  
• Deputy Head, Department of Cardiology, National Heart Centre Singapore, Nov 2013 to Dec 2021
  
• Head of Cardiology, NHCS Cardiology @ SKH, Sengkang General Hospital, 2015 to 2021
  
• Member, Medical Board, Sengkang General Hospital, 2018 to 2021
  
• Director, Coronary Care Unit, National Heart Centre Singapore, May 2011 to Apr 2019
  
• Member, Crisis Planning and Operations Taskforce Committee, National Heart Centre Singapore, Oct 2023 to Present
  
• Singapore Tourism Board Conference Ambassador, 2017 to Present
  
• Member, Cardiovascular Sciences Academic Clinical Programme (CVS ACP) Research EXCO, May 2022 to Present
  
• Member, Medical Advisory Committee of the Ministry of Home Affairs (National Emergency Medical Services), 2013 to Present
  
• Member, SAF Specialist Advisory Board in Cardiology, Jan 2023 to Present
  
• Chair, Continental Council World Heart Federation, 2018
• Board member, World Heart Federation, 2023 to 2024
  
• President, Singapore Cardiac Society, 2018 to 2019
  
• Board member, Singapore Heart Foundation, 2019 to Present
  
• President, Asian Pacific Society of Cardiology, 2019 to 2021
  
• President, International Society of Cardiovascular Pharmacotherapy, 2021
  
• Clinical Associate Professor, Duke-NUS Medical School
  
• Adjunct Assistant Professor, Lee Kong Chian School of Medicine
• Clinical Associate Professor, SingHealth Duke-NUS Global Health Institute (SDGHI)
• Clinical Assistant Professor, NUS Yong Loo Lin School of Medicine
  

• The Long Service Medal, Prime Minister's Office, 2021
  
• The Public Administration Medal (Bronze), Prime Minister's Office, 2020
  
• Outstanding Clinical Faculty Award for Internal Medicine Residency Programme, 2015
• Top 21 Young Leaders Award: Faculty Cardiovascular Research Technologies, 2011
  
• SingHealth Service Quality Award (Silver), 2012
• SingHealth Service Quality Award (Bronze), 2009 and 2007
  
• Health Manpower Development Plan, 2007 to 2008
  

• Biomarkers for chest pains
  

• SELUTION SLR TM DeNOvo STUDY-A Prospective Randomized, Multi-centre, International, Open Label, Clinical trial comparing the Selution DEB strategy versus DES strategy (Selution DeNovo) from 2024 to current.
• Global SYMPLICITY Registry (GSR) Denervation Findings in Real World (DEFINE) – GSR DEFINE study (GSR) from 2022 to current.
• A randomized, double-blind, placebo-controlled, multicenter trial, assessing the impact of inclisiran on major adverse cardiovascular events in participants with established cardiovascular disease (VICTORION-2 PREVENT) from 2021 to current.
• Feasibility trial evaluating efficacy and safety of Solitaire TM thrombus retrieval device in the management of refractory thrombus in patients with Acute Coronary Syndrome (Solitaire ACS) from 2021 to 2023.
• Safety and performance in de novo Lesion of native coronary arteries with Magmaris (BIOSOLVE-IV) from 2017 to 2020. 
  
• A Phase 3, Multicenter, Double-blind, Randomized, Placebo-controlled, Parellel-group Study to investigate the Efficacy and Safety of CSL112 in Subjects with Acute Coronary Syndrome (AGEIS II) from 2018 to 2021.
• SingXpand “ SINGaporean Program performed with an eXPANsion medical Device “Singapore pilot study evaluating the safety and the efficacy of the intramyocardial injection of expanded CD34+ stem cells (ProtheraCytes) in the treatment of patients with De Novo Acute Myocardial infarction (SingXpand) from 2019 to 2020. 
• A prospective, single arm, multi-center, open label, non-randomized trial to further evaluate the safety of 1-month (as short as 28 days) DAPT in HBR subjects undergoing PCI with XIENCE (XIENCE) from 2018 to 2020.
• Clinical Outcomes After Deployment of the Everolimus-Eluting Platinum-Chromium Bioabsorbable Polymeric (SYNGERY) Stent in a Multicentre International All-comers Registry (SYNERGY) from 2018 to 2022. 
• Prospective, multi-center, non-interventional, single-arm, open-label registry of the Medtronic Symplicity Renal Denervation System that will document the long term safety and effectiveness of renal denervation in a real world patient population with hypertension and/ or other diseases characterized by elevated sympathetic drive (Global Simplicity Registry) from 2017 to 2019. 
• A Clinical Evaluation of the Medtronic Polymer-Free Drug-Eluting Coronary Artery Lesions: REVascularization using a non-polymeric drug ELUTing stent with Internal drug IOadiNg (RevElution Trial) (RevElution) from 2016 to 2021.

• Ex vivo differentiation of human adult bone marrow stem cells into cardiomyocyte-like cells. Shim WS, Jiang S, Wong P, Tan J, Sim E et al. Biochem Biophys Res Commun. 2004 Nov 12; 324(2):481-8.
  
• Electrocardiographical case. Acute severe chest tightness. Tan J W C, Gunasegaran K, Teo W S. Singapore Med J. 2006 Oct; 47(10):913-7.
  
• Coronary Subclavian Steal Syndrome: A rare cause of acute myocardial infarction. Tan J W C, Johan BA, Wong P. Singapore Med J. 2007; 48(1):e5.
• Ex vivo differentiation of human adult bone marrow stem cells into cardiomyocyte-like cells. Shim WS, Jiang S, Wong P, Tan J, Sim E et al. Biochem Biophys Res Commun. 2004 Nov 12; 324(2):481-8.
• Acute-on-Chronic Mesenteric Ischemia. Endovascular Today. Tan J W C, Laird JR. Jan 2008 Vol. 7; 68-72
• FDA-approved Endovascular Repair Devices for abdominal Aortic Aneurysms: A Review. Tan J W C, Yeo KK, Laird JR. J Vasc Interv Radiol. 2008 Jun;19(6 Suppl):S9-S17.
• Excimer Laser Assisted angioplasty for complex infrainguinal peripheral artery disease: A 2008 Update. Tan JW C, Yeo KK, Laird JR. J Cardiovasc Surg (Torino). 2008 Jun;49(3):329-40
• Management of antiplatelet therapy during acute percutaneous coronary intervention (PCI): New strategies and therapeutics. Tan J W C, Guo Kenneth. Ann Acad Med Singapore. 2010 Mar;39(3):221-9
• Infected Coronary Artery Pseudoaneurysm following Repeated Percutaneous Coronary Intervention. Choon Pin Lim, Kah Leng Ho, Thuan Tong Tan, Yeow Leng Chua, Sung Lung Aaron Wong, Wei Chieh Tan, and Jang Wen Su. Ann Thorac Surg. 2011 Feb;91(2):e17-9
• Long-Term Outcomes Following Coronary Bare-Metal- And Drug-Eluting-Stent Implantation: A "Real World" Comparison Amongst Diabetics With Diffuse Small Vessel Coronary Artery Disease. Angela Koh et al, Wei Chieh Tan. Coron Artery Dis. 2011 Mar;22(2):96-9
• Trans-pleural Pericardiocentesis: Revisiting an Old Technique. Kenneth Guo, Ding Zee Ping, Jack Tan. Catheterization and Cardiovascular Interventions DOI 0.1002/ccd.22977
• Percutaneous mitral valve repair with MitraClip for severe functional mitral regurgitation. Yeo KK, Ding ZP, Chua YL, Lim ST, Sin KY, Tan JW, Chiam PT, Hwang NC, Koh TH. Singapore medical journal 2013;54:e9-e12.
• Chapter 23. Chiari Network Complicating a MitraClip Procedure. In Atlas of Percutaneous Edge-to-Edge Mitral Valve Repair. Yeo KK, Chiam PTL, Tan J, Ding ZP. Springer 2013.
• How should I treat stent dislodgement in a STEMI patient resulting in dissection of left main and left circumflex arteries? Kohli SK, Lim YP, Lai SH, Tan JW, Taggart D, Kharbanda R, Carrié D, Boudou N.  EuroIntervention. 2013 Aug 22;9(4):527-31. doi: 10.4244/EIJV9I4A85.
• Coronary Perforation Complicating Percutaneous Coronary Intervention. Ang CY, J Tan. A case illustration and review. ASEAN Heart Journal. December 2014, 21:3
• Risk factors for cardiovascular events among Asian patients without pre-existing cardiovascular disease on the renal transplant wait list. Wong NY, Chin CT, Tee PS, Khin LW, Angela Koh, Kee YS, Tan Jack. ASEAN Heart Journal. April 2015, 23:1
• Incidence and predictors of stent edge medial disruption: An in vivo optical coherence tomography study. Tsunenari Soeda; Seung-Jung Park; Yangsoo Jang; Stephen Lee; Kyoichi Mizuno; Tomonori Itoh; Jack Tan Wei Chieh; Hang Lee; Haibo Jia; Bo Yu; Shiro Uemura; Yoshihiko Saito; Ik-Kyung Jang. J Am Coll Cardiol. 2015;65(10_S):. doi:10.1016/S0735-1097(15)61893-9
• Current practices in coronary artery disease evaluation of renal transplant candidates prior to renal transplantation. Ningyan Wong, Ping Sing Tee, Terence Yi-Shern Kee, and Jack Wei Chieh Tan. Proceedings of Singapore Healthcare 2015, Vol. 24(4) 213 –218
• Long-Term Clinical and Duplex Ultrasound Outcomes of Patients with Venous Access Closure using the Preclose technique in patients treated with the MitraClip procedure. Jonathan Yap, Tan JW, Koh TH, Lim ST, Yeo KK. J Invasive Cardiol. 2016 Feb;28(2):40-3. 
• High-Sensitivity Troponin Assays: Boon or Bane for the Cardiologist? Natalie Koh, Lim Swee Han, Yeo Chin Pin, Jack Tan Wei Chieh. Annals, Academy of Medicine Singapore. In print
• Models of Non-Invasive Fractional Flow Reserve Based on CT Images. Jun-Mei Zhang, Liang Zhong , Tong Luo, Aileen Mae Lomarda, Yunlong Huo, Jonathan Yap, Soo Teik Lim, Ru San Tan, Aaron Sung Lung Wong, Jack Wei Chieh Tan, Khung Keong Yeo, Jiang Ming Fam, Felix Yung Jih Keng, Min Wan, Boyang Su, Xiaodan Zhao, John Carson Allen, Ghassan S. Kassab, Terrance Siang Jin Chua, Swee Yaw Tan. PLoS ONE 11(5): e0153070. doi: 10.1371/journal.pone.0153070
• The effect of a nurse-led telephone-based care coordination program on the follow-up and control of cardiovascular risk factors in patients with coronary artery disease. NINGYAN WONG, SIANG JIN TERRANCE CHUA, FEI GAO, SOK TIANG ROSALIND SIM, DAVID MATCHAR, SUNG LUNG AARON WONG, KHUNG KEONG YEO, WEI CHIEH JACK TAN, and CHEE TANG CHIN. International Journal for Quality in Health Care, 2016, 1–6 doi: 10.1093
• Index of Microvascular Resistance and Microvascular Obstruction in Patients with Acute Myocardial Infarction. Heerajnarain Bulluck, MBBS; Nicolas Foin, PhD; Hector A. Carbrera-Fuentes, PhD; Khung K. Yeo, MBBS; Aaron S. Wong, MBBS; Jiang M. Fam, MBBS; Philip E. Wong, MBBS; Jack W. Tan, MBBS; Adrian F. Low, MBBS; Derek J. Hausenloy, PhD.  J Am Coll Cardiol Intv. 2016; 9(20):2172-2174. doi: 10.1016/j.jcin.2016.08.018
• Invasive Assessment of the Coronary Microcirculation in Reperfused ST-Segment-Elevation Myocardial Infarction Patients. Where do we stand? Heerajnarain Bulluck, Nicolas Foin, Jack W. Tan, Adrian F. Low, Murat Sezer, Derek J. Hausenloy. https://doi.org/10.1161/CIRCINTERVENTIONS.116.004373 Circulation: Cardiovascular Interventions. 2017;10:e004373
• Asia-Pacific consensus statement on the optimal use of high-sensitivity troponin assays in acute coronary syndromes diagnosis: focus on hs-TnI. Jack Wei Chieh Tan, Carolyn S P Lam, Sazzli Shahlan Kasim, Tar Choon Aw, Joel M Abanilla, Wei-Ting Chang, Van Phuoc Dang,Maria Iboleon-Dy, Sari Sri Mumpuni, Arintaya Phommintikul, Manh Cuong Ta, Punkiat Topipat, Kai Hang Yiu, Louise Cullen. Heart Asia. http://dx.doi.org/10.1136/heartasia-2016-010818
• Impact of Chronic Kidney Insufficiency on Cardiovascular Outcomes in Patients that Undergo Coronary Revascularization: A Historical Review. Koh Choong Hou, Sin Yoong Kong, Kenny, Kee Yi Shern, Terence, Tan Wei Chieh, Jack. ASEAN Heart Journal. Vol. 24, no.1, 112 – 116 (2016) ISSN: 2315-4551
• AN MHEALTH SOLUTION BASED ON SOCIAL COGNITIVE THEORY TO PROMOTE ADHERENCE TO CARDIAC REHABILITATION FOR CARDIAC PATIENT. ZHIQIANG LUO,SWEE YAW TAN,NAM BENG TAN,JACK WEI CHIEH TAN,DURAIRAJ PONRAJ.  International Journal of Advances in Computer Science and Its Applications. DOI: 10.15224/978-1-63248-109-2-13
• Prevalence of Healthcare-Associated Infections and Antimicrobial Use Among Adult Inpatients in Singapore Acute-Care Hospitals: Results From the First National Point Prevalence Survey. Yiying Cai, Indumathi Venkatachalam, Nancy W. Tee,  Thean Yen Tan,  Asok Kurup, Sin Yew Wong, Chian Yong Low,  Yang Wang, Winnie Lee, Yi Xin Liew, Brenda Ang, David C. Lye,  Angela Chow,  Moi Lin Ling, Helen M. Oh, Cassandra A. Cuvin, Say Tat Ooi, Surinder K. Pada, Chong Hee Lim, Jack Wei Chieh Tan,  Kean Lee Chew,  Van Hai Nguyen, Dale A. Fisher, Herman Goossens, Andrea L. Kwa, Paul A. Tambyah, Li Yang Hsu, and Kalisvar Marimuthu.  Clin Infect Dis (2017) 64 (suppl_2): S61-S67
• Extensive Dissection of the Left Internal Mammary Artery graft and Emergency Bail Out. Jien Sze Ho and Wei Chieh Tan Jack. Archives of Medicine. 2017 Vol.9 No. 2:11. DOI: 10.21767/1989-5216.1000212