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Dr Tan Ek Khoon

Dr Tan Ek Khoon



Specialty: Hepato-pancreato-biliary and Transplant Surgery, General Surgery

Conditions Treated by this Doctor:
Gallstones, Gallstones & Laparoscopic Cholecystectomy, Gallstones & Laparoscopic Cholecystectomy, Hepato-Pancreato-Biliary Cancers, Liver Cancer, Liver Tumours, Pancreatic Cancer, Pancreatic endocrine tumours, Pancreatic Tumours.

Clinical Appointments

  • Consultant Hepato-pancreato-biliary and Transplant Surgery Singapore General HospitalSingapore General Hospital
  • Consultant General Surgery Singapore General HospitalSingapore General Hospital

Academic Appointments

  • Yong Loo Lin School of Medcine, National University of Singapore
  • Adjunct Instructor SingHealth Duke-NUS Surgery Academic Clinical Programme


Dr Tan is a Consultant Surgeon with the Department of Hepatopancreatobiliary and Transplant Surgery, and the Department of General Surgery.

He graduated from the National University of Singapore in 2008 and completed his General Surgery training at the Singapore General Hospital. During his training, he was awarded the National Medical Research Council Overseas Research Training Fellowship to study the effects of ischemia-reperfusion injury on hepatic oval cells with Dr Ari Cohen at the Ochsner Clinic, USA. He is a Fellow of the Royal College of Surgeons (Edinburgh), and holds a Master of Medicine (Surgery) from the National University of Singapore, and a Master of Public Health from the Bloomberg School of Public Health, Johns Hopkins University. Upon completing his specialist training he underwent further subspecialty training with an American Society of Transplant Surgeons (ASTS) accredited 2-year fellowship program in abdominal organ transplantation at the Mayo Clinic (Rochester), USA.

Dr Tan’s clinical practice is focused on abdominal organ transplantation and conditions involving the liver, pancreas, and biliary tract. He adopts a collaborative multi-disciplinary approach to deliver individualized care to each patient. His clinical efforts are directed primarily at improving outcomes after organ transplantation and in the treatment of cancer.

He is committed to an academic surgical practice, with active interests in tumour biology, immunology, and novel therapeutics in the treatment of cancer. He also has research interests in health policy and data analytics, which he believes can guide decision-making for clinicians to improve healthcare standards. He is engaged in medical education and the training of budding surgeons through the use of technology and adaptive learning methods.


  • Abdominal Transplant Surgery Fellowship (Mayo Clinic, Rochester)
  • Master in Public Health (Bloomberg School of Public Health, Johns Hopkins University)
  • Certificate in Health Finance and Management (Bloomberg School of Public Health, Johns Hopkins University)
  • Fellowship Diploma of the Royal College of Surgeons (Edinburgh)
  • Master in Medicine (Yong Loo Lin School of Medicine, National University of Singapore)
  • Membership Diploma of the Royal College of Surgeons (Edinburgh)
  • Bachelor of Medicine and Bachelor of Surgery (Yong Loo Lin School of Medicine, National University of Singapore)

Professional Appointments and Committee Memberships

  • Member, American Society of Transplant Surgeons
  • Fellow, Royal College of Surgeons (Edinburgh)
  • Member, Hepatopancreatobiliary Assocation (Singapore)


  • Young Investigator Award, Asia-Pacific Hepato-Pancreato-Biliary Association
  • Course Sponsorship Award, SingHealth Surgery Academic Clinical Program
  • Overseas Research Training Fellowship, National Medical Research Council Singapore
  • Best Clinical Tutor AY12/13, Yong Loo Lin School of Medicine, National University of Singapore
  • Best Medical Officer Award, National University Hospital
  • Best House Officer Award, Singapore Health Services
  • Excellence Award (Community Service), National University of Singapore Medical Society    

Research Interests


  • HL Tan, EK Tan, JY Teo, JH Jam, SY Lee, PC Cheow, PR Jeyaraj, PK Chow, AY Chung, LL Ooi, CY Chan, BKP Goh. Outcome of minimally-invasive versus open pancreatectomies for solid pseudopapillary neoplasms of the pancreas: a 2:1 matched case-control study. Ann Hepatobiliary Pancreat Surg 2019 – Accepted PMID:31501814
  • YX Guo, EK Tan, NL Syn, TL Krishnamoorthy, CK Tan, R Lim, SY Lee, CY Chan, PC Cheow, AYF Chung, PR Jeyaraj, BKP Goh. Repeat liver resection versus salvage liver transplantation for recurrent hepatocellular carcinoma: a propensity score-adjusted and –matched comparison analysis. Ann Hepatobiliary Pancreat Surg 2019 – Accepted
  • EK Tan, AJ Bentall, PG Dean, MF Shaheen, MD Stegall, CA Schinstock. Use of eculizumab for active antibody-mediated rejection that occurs early post-kidney transplantation: A consecutive series of 15 cases. Transplantation 2019 – Online first PMID:30801549
  • YX Guo, EK Tan, TL Krishnamoorthy, CK Tan, BH Tan, TT Tan, SY Lee, CY Chan, PC Cheow, AYF Chung, PR Jeyaraj, BKP Goh. Outcomes of salvage liver transplant for recurrent hepatocellular carcinoma: A comparison with primary liver transplant. Ann Hepatobiliary Pancreat Surg 2019;23(1):1-7 PMID:30863801
  • SY Lee, BKP Goh, G Sepideh, JC Allen, RP Merkow, JY Teo, D Chandra, YX Koh, EK Tan, JH Kam, PC Cheow, PKH Chow, LLPJ Ooi, AYF Chung, MI D’Angelica, WR Jarnagin, TP Kingham, CY Chan. Laparoscopic liver resection difficulty score – a validation study. J Gastrointest Surg 2019;23:545 PMID:30421119
  • EK Tan, BKP Goh, SY Lee, TL Krishnamoorthy, CK Tan, PR Jeyaraj. Liver transplant waitlist outcomes and the allocation of HCC MELD exception points at a low-volume center. Transplant Proc 2018;50(10):3564-70 PMID:30577239
  • D Chua, A Low, YX Koh, PC Cheow, JH Kam, JY Teo, EK Tan, A Chung, LL Ooi, CY Chan, SY Lee. A retrospective review of correlative radiological assessment and surgical exploration for hilar cholangiocarcinoma. Ann Hepatobiliary Pancreat Surg 2018;22(3):216-22 PMID:30215043
  • Chin KM, Allen JC, Teo JY, Kam JH, Tan EK, Koh YX, Goh KPB, Cheow PC, Raj P, Chow KHP, Chung YFA, Ooi LL, Chan CY, Lee SY. Predictors of post-hepatectomy liver failure in patients undergoing extensive liver resections for hepatocellular carcinoma. Ann Hepatobiliary Pancreat Surg 2018;22(3):185-96 PMID:30215040
  • Ye QJ, Desai SR, EK Tan. A case of melioidosis presenting as acalculous cholecystitis. Cureus 2018;22(10):e2864 PMID:30148016
  • EK Tan, M Shuh, H Francois-Vaughan, J Sanders, AJ Cohen. Negligible oval cell proliferation following ischemia/reperfusion injury with and without partial hepatectomy. Ochsner J 2017;17(1):31-37 PMID:28331445
  • EK Tan, M Shuh, AJ Cohen. Liver injury models for induction of hepatic oval cells in rodents. J Liver Res Disord Ther 2015;1(1):00005 DOI:10.15406/jlrdt.2015.01.00005
  • VG Shelat, EK Tan, LT Teo, V Appasamy, MT Chiu. Outcomes of Nonoperative Management of Blunt Splenic Injury – Asian Experience. Int Surg 2015;100(9-10):1281-6 DOI:10.9738/INTSURG-D-14-00160.1
  • EK Tan, SG Tan. The Permanent Catheter. Hemodial Int 2014;18(2):522-4 PMID:24164973
  • EK Tan, VTW Lee, SKY Chang, IS Ganpathi, K Madhavan. Laparo-endoscopic single-site minor hepatectomy for liver tumors. Surgical Endoscopy 2012; 26(7): 2086-91 PMID:22234591
  • EK Tan, VG Shelat, LT Teo, MT Chiu. Peritoneo-cutaneous fistula secondary to skin excoriation from a large chronic incisional hernia. Ann Acad Med Singapore 2010;39:872-3 PMID:21165530
  • EK Tan, PJLL Ooi. Colorectal cancer liver metastases – understanding the differences in the management of synchronous and metachronous disease. Ann Acad Med Singapore 2010; 39: 719-33 PMID:20957308
  • EK Tan, WL Chung, YJ Lew, A Tan, MY Chan, BC Tai, WP Koh. Characteristics, control and complications of hypertensive patients in primary care – a community-based study in Singapore. Ann Acad Med Singapore 2009;38:5806 PMID:19890575

Research Trials