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Clin Assoc Prof Christopher Khor Jen Lock

Clin Assoc Prof Christopher Khor Jen Lock


Senior Consultant

Specialty: Gastroenterology & Hepatology

Sub-specialties: Advanced Endoscopic Imaging, Diagnostic and Therapeutic Endoscopy, Gastrointestinal Stenting, Endoscopic Ultrasound (EUS), Endoscopic Retrograde Cholangio-Pancreatography (ERCP), Colon Cancer Screening, Endoscopic Mucosal Resection (EMR) and Endoscopic Submucosal Dissection (ESD), Endoscopic Therapy of early Gastrointestinal Cancer, Peroral Endoscopic Myotomy (POEM), Pancreaticobiliary Disorders

Conditions Treated by this Doctor:
Achalasia, Biliary Stones (Choledocholithiasis), Colon Cancer Screening, Colonic Polyps, Complex Colonic Polyps, Early Cancer of the Esophagus, Stomach & Colon, Gastrointestinal Luminal Stenosis, General Gastroenterology, Pancreatic & Hepatobiliary Cancer, Pancreatic Cysts & Nodules, Subepithelial/Submucosal Lesions.

Clinical Appointments

  • Senior Consultant Gastroenterology & Hepatology Singapore General HospitalSingapore General Hospital

Academic Appointments

  • Clinical Teacher, Lee Kong Chian School of Medicine
  • Clinical Associate Professor, Duke-NUS Graduate Medical School
  • Clinical Senior Lecturer, Yong Loo Lin School of Medicine, NUS


​Assoc Prof Christopher Khor attended medical school at NUS, and completed advanced clinical fellowships in ERCP and in Endoscopic Ultrasound (EUS) at the Medical University of South Carolina and Indiana University Medical Center respectively. More recently, he trained in Endoscopic Submucosal Dissection in Japan. His main practice areas are in pancreato-biliary disease (ERCP and EUS), endoscopic resection and other advanced endoscopic therapies, and in general gastroenterology.

Dr Khor has a keen interest in endoscopic quality and education, and in promoting cross-border co-operation among the regional endoscopy community.  His regional work includes regular faculty invitations to demonstrate and teach endoscopy. He has more than 40 peer-reviewed papers to his name, and is a reviewer for endoscopy and GI journals. Dr Khor currently co-chairs an Asia-Pacific group focused on EUS education. He served as Vice-President of Asian-Pacific Digestive Week 2011 in Singapore, for which he directed Endoscopy programming, is a past President of the Gastroenterological Society of Singapore, and is the immediate past Chairman of the Chapter of Gastroenterologists, Academy of Medicine Singapore.


  • ​2012   Fellow of the American Society of Gastrointestinal Endoscopy (FASGE)
  • 2006   Fellow of the Royal College of Physicians (Edinburgh) – FRCP(Edinburgh)
  • 2000   Specialist Accreditation in Gastroenterology, Singapore Medical Council
  • 2000   Fellow of the Academy of Medicine of Singapore (FAMS)
  • 1992   Membership of the Royal College of Physicians, United Kingdom – MRCP(UK)
  • 1987   Bachelor of Medicine, Bachelor of Surgery (MBBS), National University of Singapore

Professional Appointments and Committee Memberships

  • Adjunct Associate Professor, Duke-NUS Medical School
  • Clinical Senior Lecturer, Yong Loo Lin School of Medicine, NUS
  • Chairman, Chapter of Gastroenterologists, College of Physicians, Academy of Medicine 2015-2017
  • Board member, Chapter of Gastroenterologists, College of Physicians, Academy of Medicine 2008-present
  • Editorial Board Member, Endoscopic Ultrasound 2012-present
  • Member, Asian Telemedicine Working Group
  • Co-chair, EUS Taskforce Asia-Pacific (EUS-TAP), 2012- present
  • Visiting Senior Consultant, Khoo Teck Puat Hospital 2010-present
  • Editorial Board Member, Endoscopy (Thieme)  2005-2014
  • President, Gastroenterological Society of Singapore 2010-2012
  • Vice-President, Asian Pacific Digestive Week (APDW) 2011, Singapore
  • Co-director, Live Endoscopy Workshop & Director of Endoscopy Programming, APDW 2011
  • Independent Medical Expert, Academy of Medicine/Subordinate Courts 2008
  • External evaluator, Centre for Drug Administration, Health Sciences Authority, Singapore


  • ​National Excellent Service Award- Gold (EXSA) 2007 & 2009
  • National Healthcare Group Quality Pillar Award 2008
  • Senior Health Manpower Development Programme Fellowship 2007 in Endoscopic Submucosal Dissection
  • Health Manpower Development Programme Fellowship 1998-99 in Therapeutic Endoscopy & Pancreatic Disease

Research Interests

  • Pancreato-biliary endoscopy
  • Pathogenesis and Endoscopic therapy of early gastrointestinal malignancy
  • Medical device development


  • ​Ong AM, Chua LT, Khor CJ, Asokkumar R, Namasivayam V, Wang YT.  Diaphragmatic Breathing Reduces Belching and Proton Pump Inhibitor Refractory Gastroesophageal Reflux Symptoms. Clin Gastroenterol Hepatol. 2017 Nov 2 [Epub ahead of print].
  • Liew ZH, Loh TJZ, Lim TKH, Lim TH, Khor CJL, Mesenas SJ, Kong CSC, Ong WC, Tan DMY. Role of fluorescence in situ hybridization in diagnosing cholangiocarcinoma in indeterminate biliary strictures.  Gastroenterol Hepatol. 2017 May 19 [Epub ahead of print].
  • Stanley AJ, Laine L, Dalton HR, Ngu JH, Schultz M, Abazi R, Zakko L, Thornton S, Wilkinson K, Khor CJ, Murray IA, Laursen SB; International Gastrointestinal Bleeding Consortium. Comparison of risk scoring systems for patients presenting with upper gastrointestinal bleeding: international multicentre prospective study. BMJ. 2017 Jan 4;356:i6432.
  • Najib Azmi A, Khor CJ, Ho KY, Pittayanon R, Rerknimitr R, Ratanachu-Ek T, Koay DS, Koh JC, Ho SH, Goh KL, Mahadeva S. Endoscopic Submucosal Dissection Outcomes for Gastroesophageal Tumors in Low Volume Units: A Multicenter Survey. Diagn Ther Endosc. 2016;2016:5670564.
  • Liao WC, Angsuwatcharakon P, Isayama H, Dhir V, Devereaux B, Khor CJ, Ponnudurai R, Lakhtakia S, Lee DK, Ratanachu-Ek T, Yasuda I, Dy FT, Ho SH, Makmun D, Liang HL, Draganov PV, Rerknimitr R, Wang HP. Gastrointest Endosc. 2017 Feb;85(2):295-304.
  • Murdani A, Kumar A, Chiu HM, Goh KL, Jang BI, Khor CJ, Lau J, et al. WEO position statement on hygiene in digestive endoscopy: Focus on endoscopy units in Asia and the Middle East. Dig Endosc. 2017 Jan;29(1):3-15.
  • Asokkumar R, Tan D, Khor C, Soetikno R. Direct visualization of biliary stricture through a colonoscope in a patient with Roux-en-Y hepaticojejunostomy. Gastrointest Endosc. 2016 Apr 2. S0016-5107(16)30008-6.
  • Isayama H, Nakai Y, Rerknimitr R, Khor C, Lau J, Wang HP, et al. The Asian consensus statements on endoscopic management of walled-off necrosis Part1: Epidemiology, diagnosis and treatment. J Gastroenterol Hepatol. 2016 Apr 4.
  • Isayama H, Nakai Y, Rerknimitr R, Khor C, Lau J, Wang HP, et al. The Asian consensus statements on endoscopic management of walled-off necrosis Part2: Endoscopic management. J Gastroenterol Hepatol. 2016 Apr 4.
  • Kim TH, Kim JH, Seo DW, Lee DK, Reddy ND, Rerknimitr R, Ratanachu-Ek T, Khor CJ, Itoi T, Yasuda I, Isayama H, Lau JY, Wang HP, Chan HH, Hu B, Kozarek RA, Baron TH. International consensus guidelines for endoscopic papillary large-balloon dilation. Gastrointest Endosc. 2016 Jan;83(1):37-47.
  • Goh BK, Lin Z, Tan DM, Thng CH, Khor CJ, Lim TK, Ooi LL, Chung AY. Evaluation of the Fukuoka Consensus Guidelines for intraductal papillary mucinous neoplasms of the pancreas: results from a systematic review of 1382 surgically-resected patients. Surgery. 2015 Nov;158(5):1192-202.
  • Chin YK, Tan DM, Lim KH, Khor CJ. A case of unusual indeterminate biliary stricture. Gastrointest Endosc. 2015 Jul;82(1):168.
  • Ramchandani M, Reddy DN, Lakhtakia S, Tandan M, Maydeo A, Chandrashekhar TS, Kumar A, Sud R, Rerknimitr R, Makmun D, Khor CJ. Per oral cholangiopancreatoscopy in pancreatico biliary diseases - expert consensus statements. World J Gastroenterol. 2015 Apr 21;21(15):4722-34
  • Lim LG, Ho KY, So JB, Khor CJ, Lim LL, Teoh PL, Yeoh KG. Diagnosis and treatment of Helicobacter pylori for peptic ulcer bleeding in clinical practice - factors associated with non-diagnosis and non-treatment, and diagnostic yield in various settings. Turk J Gastroenterol. 2014 Dec;25 Suppl 1:157-61.
  • EWL Wee & CJL Khor. Chapter 3: Non-Variceal Upper GI Hemorrhage and Endoscopic Management. Chapter 4: Upper GI Variceal Hemorrhage and Endoscopic Management; in Atlas of Complicated Abdominal Emergencies, Eds. TK Ti & D Lomanto, World Scientific Publishing Co. Ltd. 2014
  • Kongkam P, Devereaux BM, Ponnudurai R, Ratanachu-ek T, Sahai AV, et al., Khor CJL. Endoscopic Ultrasound Forum Summary from the Asian Pacific Digestive Week 2012. Endoscopic Ultrasound 2013, 2(1):43-60
  • Rerknimitr R, Angsuwatcharakon P, Ratanachu-ek T, Khor CJ, Ponnudurai R, Moon JH, Seo DW, Pantongrag-Brown L, Sangchan A, Pisespongsa P, Akaraviputh T, Reddy ND, Maydeo A, Itoi T, Pausawasdi N, Punamiya S, Attasaranya S, Devereaux B, Ramchandani M, Goh KL. Asia-Pacific consensus recommendations for endoscopic and interventional management of hilar cholangiocarcinoma. J Gastroenterol Hepatol. 2013 Apr;28(4):593-607.
  • Lim LG, Lakhtakia S, Ang TL, Vu CK, Dy F, Chong VH, Khor CJ, et al. Factors Determining Diagnostic Yield of Endoscopic Ultrasound Guided Fine-Needle Aspiration for Pancreatic Cystic Lesions: A Multicentre Asian Study. Dig Dis Sci. 2013 Jan 13.
  • Khor CJL, Hartono JL, Current guidelines for endoscopy in patients on antithrombotic medication. Gastrointest Interv 2012; 1:58-62.
  • Itoi T, Khor CJ. Management of benign strictures of the extrahepatic bile duct due to chronic pancreatitis and surgical intervention. Dig Endosc. 2012 May;24 Suppl 1:8-16.

Research Trials