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Prof Ecosse Lamoureux

Prof Lamoureux Ecosse

​BEd, GradDip, MApplSc, PhD 

Academic Appointments

  • Professor SingHealth Duke-NUS Ophthalmology & Visual Sciences Academic Clinical Programme


Prof Ecosse Lamoureux is a tenured Professor with the Duke-NUS Medical School. He undertakes his clinical research at the Singapore Eye Research Institute where he is the Director of the Population Research and Clinical Epidemiology platform.

His research program includes the implementation of novel RCTs; population-based epidemiology studies; prevention and treatment models for vision impairment and care; adherence to management of eye diseases; and patient-centred outcomes. To date, his overall research activities have attracted over S$$41 million in competitive grant funding, which include multiple top-tier individual grants in Australia and Singapore. He currently holds a Singapore Clinician Scientist Award (Senior Category).

His contribution to population eye health research is significant. He leads the patient-reported outcomes research component of the Singapore Epidemiology of Eye Diseases (SEED) programme and has contributed significantly to the better understanding of the economic, social and personal burden; and considerable impact of vision impairment and ocular pathologies in Singapore and Asia. His recent work includes a large population-based study to better understand the burden and complex mechanisms underlying age-related sensory decline in Singapore.

To date, he has ~420 publications in top international journals, with a current H and i10-indices of 59 and 267, respectively.


  • PhD (2001)
  • MApplSc (1996)
  • GradDip (1992)
  • Bed (1992)

Professional Appointments and Committee Memberships

  • Professorial Fellow (Adjunct), Department of Surgery and Medicine, University of Melbourne, Australia (2018 - present)
  • Professor, Department of Ophthalmology, National University of Singapore (2015 - present)
  • Professor, Health Services and Systems Research, Duke-NUS Medical School (2015 - present)
  • Professor, Office of Clinical Sciences, Duke NUS Medical School, Singapore (2013 - present)


  • Asia-Pacific Academy of Ophthalmology (APAO) Achievement Award (2017)
  • APAO Outstanding Service in Prevention of Blindness Award (2015)
  • Senior Research Fellowship-Level B, NHMRC (2013 – 2015)
  • Career Development Award Fellowship, NHMRC (2009 – 2012)
  • Public Health Postdoctoral Fellowship, NHMRC (2005 – 2009)

Research Interests

  • Health Services and Translational Eye Research
  • Ocular Epidemiology
  • Patient-Centred Outcomes in Eye


  1. Kidd Man RE, Liang Gan AT, Fenwick EK, Gupta P, Thakur S, Fang XL, Cheng CY, Wong TY, Lamoureux, E.L. The Differential Impact of Age on Vision-Related Quality of Life across the Visual Impairment spectrum. Ophthalmology. 2020 Jul 29:S0161-6420(20)30731-4. doi: 10.1016/j.ophtha.2020.07.046. Online ahead of print.

  2. Zheng F, Wong CW, Sabanayagam C, Cheung YB, Matsumura S, Chua J, Man REK, Ohno-Matsui K, Wong TY, Cheng CY, Tai ES, Lamoureux, E.L., Schmetterer L, Kuo A, Hoang QV, Saw SM. Acta Prevalence, risk factors and impact of posterior staphyloma diagnosed from wide-field optical coherence tomography in Singapore adults with high myopia. Ophthalmol. 2020 Jun 29. doi: 0.1111/aos.14527. Online ahead of print.

  3. Fenwick EK, Man RE, Aung T, Ramulu P, Lamoureux, E.L. Beyond intraocular pressure: Optimizing patient-reported outcomes in glaucoma. Prog Retin Eye Res. 2020 May;76:100801.

  4. Kidd Man RE, Liang Gan AT, Fenwick EK, Thakur S, Gupta P, Teo ZL, Cheng CY, Wong TY, Lamoureux, E.L. Using Uniocular Visual Acuity Substantially Underestimates the Impact of Visual Impairment on Quality of Life Compared with Binocular Visual Acuity.  Ophthalmology. 2020 Feb 8. pii:S0161-6420(20)30141-X. doi:10. 1016 /j.ophtha.2020.01.056.

  5. Ting DSW, Cheung CY, Nguyen Q, Sabanayagam C, Lim G, Lim ZW, Tan GSW, Soh YQ, Schmetterer L, Wang YX, Jonas JB, Varma R, Lee ML, Hsu W, Lamoureux, E.L., Cheng CY, Wong TY. Deep learning in estimating prevalence and systemic risk factors for diabetic retinopathy: a multi-ethnic study. NPJ Digit Med. 2019 Apr 10;2:24. doi:0.1038/s41746-019-0097-x. eCollection 2019.

Research Trials

  • ​Computerized Adaptive Testing (CAT) Technologies to Improve Patient-Provider Experience and Healthcare Outcomes for Patients (2019-2020)
  • An Intensive, Practical, and Personalized Care Planning to Improve Glycemic Control, Clinical, Ocular, And Patient Centred Outcomes in Poorly Controlled Patients with Diabetic Retinopathy (2018-2022)
  • TAAP: Translational Asian Age-related macular degeneration Program (2018-2022)
  • Optimising the assessment of quality of life in glaucoma using item bank and computer adaptive testing systems (2018-2020)
  • Application and Evaluation of an Artificial Intelligence Deep Learning System to Detect Referable and Sight-threatening Retinal Diseases in the Singapore Integrated Diabetic Retinopathy Screening Programme (SiDRP): Screening Performance and Cost-effectiveness Analysis (2018-2020)
  • An Innovative and Patient-Centric Research Program Targeting the Ageing Singaporeans: The PRevention of and interVentIon for eye Diseases in the Elderly [PROVIDE] programme (2017 – 2021)
  • Visually-Disabling Pathologic Myopia in the SEED and SCORM High Myopia Cohorts: Longitudinal Changes, Novel Biomarkers and Impact on Health Related Quality of Life (2017-2020)
  • Development of a novel utility measure using discrete choice experiments to assess the impact of glaucoma treatments from the patient’s perspective (2017-2020)
  • The Singapore diabetes complications study: Closing the screening-referral uptake loop for diabetic retinopathy, nephropathy, and foot complications (2016 – 2020)
  • The Clinical and Economic Effectiveness of Extending Diabetic Eye Screening in Singapore (2016-2020)