MBBS, M Med(Ophth), FRCS(Ed), FRCOphth, FAMS, PhD (Lond)
Conditions Treated by this Doctor:
Professor Aung Tin is a clinician scientist in ophthalmology and currently Executive Director of the Singapore Eye Research Institute (SERI); Senior Consultant, Glaucoma Department and Deputy Medical Director (Research) of the Singapore National Eye Centre (SNEC). He is also a full tenured Professor with the Department of Ophthalmology, Yong Loo Lin School of Medicine, National University of Singapore, and in 2018, he was conferred the Kwan Im Thong Hood Cho Temple Professorship of Ophthalmology, Duke-NUS Medical School, Singapore.
Professor Aung’s research has secured more than S$20 million in competitive research grant funding. He is a NMRC STAR Investigator since 2015, previously CSA (Junior) from 2007-2010 and CSA (Senior) from 2008-2013. He was awarded the Nakajima Award (2007) and De Campo Award (2013) by the Asia Pacific Academy of Ophthalmology, the Alcon Research Institute Award (2013), the Singapore Translational Research (STaR) Investigator Award (2014), the Robert Ritch Award for Excellence and Innovation in Ophthalmology by the Glaucoma Foundation (2017), as well as numerous other awards/medals.
Professor Aung Tin currently has more than 600 publications including 15 major papers in Nature Genetics (6 as First or last author) as well as papers in JAMA and Lancet. He has delivered more than 100 Invited Lectures at many international meetings. He is on the Editorial Board of 7 journals (including Ophthalmology, Progress in Retinal and Eye Research, Journal Of Glaucoma, Eye and Graefe’s Archive for Clinical Exp Ophthalmology; and a regular reviewer for more than 20 journals.
Professor Aung was President of the World Glaucoma Association from 2016-2017, and also serves as Board Member of the WGA and Asia Pacific Glaucoma Society. He was President of the College of Ophthalmologists of Singapore from 2012-2014 and President of the Singapore Society of Ophthalmology from 2009-2011.Professor Aung is actively involved in medical education of undergraduates and post graduates. He supervises and mentors Research Fellows, Trainees and Students, especially in the areas of glaucoma and translational research.
Genetics of Glaucoma in People of African Descent (GGLAD) Consortium., Hauser MA, Allingham RR, Aung T, Van Der Heide CJ, Taylor KD, Rotter JI, Wang SJ, Bonnemaijer PWM, Williams SE, Abdullahi SM, Abu-Amero KK, Anderson MG, Akafo S, Alhassan MB, Asimadu I, Ayyagari R, Bakayoko S, Nyamsi PB, Bowden DW, Bromley WC, Budenz DL, et al. Association of Genetic Variants With Primary Open-Angle Glaucoma Among Individuals With African Ancestry. JAMA. 2019 Nov 5;322(17):1682-1691.
He M, Jiang Y, Huang S, Chang DS, Munoz B, Aung T, Foster PJ, Friedman DS.Laser peripheral iridotomy for the prevention of angle closure: a single-centre, randomised controlled trial. Lancet. 2019 Apr 20;393(10181):1609-1618.
Jonas JB, Aung T, Bourne RR, Bron AM, Ritch R, Panda-Jonas S. Glaucoma. Lancet. 2017 Nov 11;390(10108):2183-2193.
Aung T, Ozaki M, Lee MC, Schlötzer-Schrehardt U, ……… Khor CC. Genetic association study of exfoliation syndrome identifies a protective rare variant at LOXL1 and five new susceptibility loci. Nature Genetics. 2017 Jul;49(7):993-1004.
Khor CC, Do T, Jia H, Nakano M, George R, …. Aung T. Genome-wide association study identifies five new susceptibility loci for primary angle closure glaucoma. Nature Genetics 2016 May;48(5):556-62.
Aung T, Ozaki M, Mizoguchi T, Allingham RR, …. Khor CC. A common variant mapping to CACNA1A is associated with susceptibility to Exfoliation syndrome. Nature Genetics 2015 Apr;47(4):387-92.
Chen Y, Lin Y, Vithana EN, Jia L, Zuo X, Wong TY, Chen LJ, Zhu X, Tam POS, Gong B, Qian S, Li Z, Liu X, Mani B, Luo Q, Guzman C, Leung CKS, Li X, Cao W, Yang Q, Tham CCY, ChengY, Zhang X, Wang N, Aung T, Khor CC, Pang CP, Sun X, Yang Z. Common variants near ABCA1 and in PMM2 are associated with primary open-angle glaucoma. Nature Genetics 2014; 46(10): 1115-9.
Weinreb RN, Aung T, Medeiros FA. The Pathophysiology and Treatment of Glaucoma: A Review. JAMA. 2014 May 14;311(18):1901-11
Hysi PG, Cheng CY, Springelkamp H, Macgregor S, ………..Aung T. Genome-wide Analysis of Multiethnic Cohorts Identifies Four New Loci Influencing Susceptibility to Increased Intraocular Pressure and Susceptibility to Glaucoma. Nature Genetics- 2014; 46(10): 1126-30.
Nongpiur ME, Khor CC, Jia H, Nair KS, …. Aung T. ABCC5, a gene that influences the anterior chamber depth, is associated with primary angle closure glaucoma. PLoS Genet. 2014; 10(3): e1004089.
Vithana EN, Khor CC, Qiao C, Nongpiur ME, ……… Aung T. Genome-wide association analyses identify three new susceptibility loci for Primary Angle Closure Glaucoma. Nature Genetics. 2012 Oct;44(10):1142-6.
Vithana EV, Morgan P, Sundaresan P, Ebenezer N…….., Aung T. Mutations in Na-borate co-transporter SLC4A11 cause recessive Congenital Hereditary Endothelial Dystrophy, CHED2. Nature Genetics, 2006; 38: 755-7.
Current Research Funding Support
Commercial Research Grants
Executive Director, Singapore Eye Research Institute
Executive Director, Singapore Eye Research Institute
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