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Recent advances in our understanding of the pathogenesis of juvenile idiopathic arthritis and their potential clinical implications. Leong JY, Guan YJ, Albani S, Arkachaisri T. Expert Rev Clin Immunol. 2018 Nov;14(11).

Molecular mechanisms of autophagic memory in pathogenic T cells in human arthritis. Kumar P, Yao LJ, Saidin S, Paleja B, van Loosdregt J, Chua C, Arkachaisri T, Consolaro A, Gattorno M, Martini A, Pischel KD, Williams GW, Lotz M, Albani S. J Autoimmun. 2018 Nov;94:90-98.

Multidimensional analyses reveal distinct immune microenvironment in hepatitis B virus-related hepatocellular carcinoma. Lim CJ, Lee YH, Pan L, Lai L, Chua C, Wasser M, Lim TKH, Yeong J, Toh HC, Lee SY, Chan CY, Goh BK, Chung A, Heikenwälder M, Ng IO, Chow P, Albani S, Chew V. Gut. 2018 Jul 3. pii: gutjnl-2018-316510.

A systematic approach to the development of a safe live attenuated Zika vaccine. Kwek SS, Watanabe S, Chan KR, Ong EZ, Tan HC, Ng WC, Nguyen MTX, Gan ES, Zhang SL, Chan KWK, Tan JH, Sessions OM, Manuel M, Pompon J, Chua C, Hazirah S, Tryggvason K, Vasudevan SG, Ooi EE. Nat Commun. 2018 Mar 12;9(1):1031.

An automated staining protocol for seven-colour immunofluorescence of human tissue sections for diagnostic and prognostic use. Lim JCT, Yeong JPS, Lim CJ, Ong CCH, Wong SC, Chew VSP, Ahmed SS, Tan PH, Iqbal J. Pathology. 2018 Apr;50(3):333-341.

Immune activation underlies a sustained clinical response to Yttrium-90 radioembolisation in hepatocellular carcinoma. Chew V, Lee YH, Pan L, Nasir NJM, Lim CJ, Chua C, Lai L, Hazirah SN, Lim TKH, Goh BKP, Chung A, Lo RHG, Ng D, Filarca RLF, Albani S, Chow PKH. Gut. 2019 Feb;68(2):335-346.

Early molecular correlates of adverse events following yellow fever vaccination. Chan CY, Chan KR, Chua CJ, Nur Hazirah S, Ghosh S, Ooi EE, Low JG. JCI Insight. 2017 Oct 5;2(19).

Increased autophagy contributes to the inflammatory phenotype of juvenile idiopathic arthritis synovial fluid T cells. Peeters JGC, de Graeff N, Lotz M, Albani S, de Roock S, van Loosdregt J. Rheumatology (Oxford). 2017 Oct 1;56(10):1694-1699.

Precision medicine in pediatric rheumatology. Yeo JG, Ng CT, Albani S. Curr Opin Rheumatol. 2017 Sep;29(5):500-505.

Human neonatal thymectomy induces altered B-cell responses and autoreactivity. van den Broek T, Madi A, Delemarre EM, Schadenberg AWL, Tesselaar K, Borghans JAM, Nierkens S, Redegeld FA, Otten HG, Rossetti M, Albani S, Sorek R, Cohen IR, Jansen NJG, van Wijk F. Eur J Immunol. 2017 Nov;47(11):1970-1981.

Delineation of an immunosuppressive gradient in hepatocellular carcinoma using high-dimensional proteomic and transcriptomic analyses. Chew V, Lai L, Pan L, Lim CJ, Li J, Ong R, Chua C, Leong JY, Lim KH, Toh HC, Lee SY, Chan CY, Goh BKP, Chung A, Chow PKH, Albani S. Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):E5900-E5909.

Human fetal dendritic cells promote prenatal T-cell immune suppression through arginase-2. McGovern N, Shin A, Low G, Low D, Duan K, Yao LJ, Msallam R, Low I, Shadan NB, Sumatoh HR, Soon E, Lum J, Mok E, Hubert S, See P, Kunxiang EH, Lee YH, Janela B, Choolani M, Mattar CNZ, Fan Y, Lim TKH, Chan DKH, Tan KK, Tam JKC, Schuster C, Elbe-Bürger A, Wang XN, Bigley V, Collin M, Haniffa M, Schlitzer A, Poidinger M, Albani S, Larbi A, Newell EW, Chan JKY, Ginhoux F. Nature. 2017 Jun 29;546(7660):662-666.

Singlet gating in mass cytometry. Lai L, Yeo JG, Albani S. 2017 July. Cytometry A. 2017 Feb;91(2):170-172.

Epipolymorphisms associated with clinical outcome of arthritis affect T-cell activation pathways. Spreafico R, Rossetti M, Whitaker JW, Wang W, Lovell DJ, Albani S. Proc Natl Acad Sci U S A. 2016 Nov 29;113(48).

Increased autophagy in CD4+ T cells of rheumatoid arthritis patients results in T-cell hyperactivation and apoptosis resistance. van Loosdregt J, Rossetti M, Spreafico R, Moshref M, Olmer M, Williams GW, Kumar P, Copeland D, Pischel K, Lotz M, Albani S. Eur J Immunol. 2016 Dec;46(12):2862-2870.

Enhancing translational research in paediatric rheumatology through standardization. Yeung RS, Albani S, Feldman BM, Mellins E, Prakken B, Wedderburn LR. Nat Rev Rheumatol. 2016 Nov;12(11):684-690.

TCR repertoire sequencing identifies synovial Treg cell clonotypes in the bloodstream during active inflammation in human arthritis. Rossetti M, Spreafico R, Consolaro A, Leong JY, Chua C, Massa M, Saidin S, Magni-Manzoni S, Arkachaisri T, Wallace CA, Gattorno M, Martini A, Lovell DJ, Albani S. Ann Rheum Dis 2017;76:435–441.

The role of nuclear factor-kappa B and endoplasmic reticulum stress in hepatitis B viral-induced hepatocellular carcinoma. Yeong J, Chew V. Transl Cancer Res 2016;5(S1):S13-S17.

Using a theragnostic approach in Juvenile Idiopathic Arthritis. Leong JY, Albani S. Expert Opinion on Orphan Drugs 2016;Volume 4-Issue 3.

Interaction between tumour-infiltrating B cells and T cells controls the progression of hepatocellular carcinoma. Garnelo M, Tan A, Her Z, Yeong J, Lim CJ, Chen J, Lim KH, Weber A, Chow PKH, Chung A, Ooi LL, Toh HC, Heikenwalder M, Ng I, Nardin A, Chen Q, Abastado J, Chew V. Gut. 2017 Feb;66(2):342-351.

TLR3 agonist and Sorafenib combinatorial therapy promotes immune activation and controls hepatocellular carcinoma progression. Ho V, Lim TS, Lee J, Steinberg J, Szmyd R, Tham M, Yaligar J, Kaldis P, Abastado JP, Chew V. Oncotarget. 2015 Sep 29;6(29):27252-66.

PD-1 expression on dendritic cells suppresses CD8+ T cell function and antitumor immunity. Lim TS, Chew V, Sieow JL, Goh S, Yeong JP, Soon AL, Ricciardi-Castagnoli P. Oncoimmunology. 2015 Aug 31;5(3):e1085146.

A CD45-based barcoding approach to multiplex mass-cytometry (CyTOF). Lai LY, Ong R, Li J, Albani S. Cytometry A. 2015 Apr;87(4):369-74.

Ex vivo-expanded, but not in vitro-induced, human regulatory T cells are suitable for cell therapy in rheumatological autoimmune diseases thanks to stable FOXP3 demethylation. Rossetti M, Spreafico R, Saidin S, Chua C, Moshref M, Leong JY, Tan YK, Thumboo J, van Loosdregt J, Albani S. J Immunol. 2015 Jan 1; 194(1): 113–124.

A circulating reservoir of pathogenic-like CD4+ T cells shares a genetic and phenotypic signature with the inflamed synovial micro-environment. Spreafico R, Rossetti R, van Loosdregt J, Wallace CA, Massad M, Magni-Manzoni S, Gattorno M, Martini A, Lovell DJ and Albani S. Ann Rheum Dis. 2016 Feb;75(2):459-65.

A sensitive protocol for FOXP3 epigenetic analysis in scarce human samples. Spreafico R, Rossetti M, van den Broek T, Jansen NJ, Zhang H, Moshref M, Prakken B, van Loosdregt J, van Wijk F, Albani S. Eur J Immunol. 2014 Oct;44(10):3141-3.

The eye: A window of opportunity in rheumatoid arthritis? Tong L, Thumboo J, Tan YK, Wong TY, Albani S. Nat Rev Rheumatol. 2014 Sep;10(9):552-60.

A115: deep immunophenotyping in the identification of clinically meaningful immune signatures in juvenile idiopathic arthritis. Spreafico R, Rossetti M, Lovell DJ, Albani S. Arthritis & Rheumatology. 2014;Vol.66(S3).

Startups on the menu: Archimedes. Albani S. Nature Biotechnology volume 31, page 1074 (2013).