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Health Services Research and Evaluation


Quadruple Aim Framework

SingHealth Regional Health System seeks the simultaneous improvement of the four dimensions under the Quadruple Aim Framework – population health, patient experience of care, per capita cost and overall satisfaction of healthcare providers.

Population health involves personal, behavioural and environmental factors affecting health outcomes, as well as the policies and interventions that link these factors.

The SingHealth Health Services and Research Evaluation (HSRE) team conducts and facilitates programme evaluation and population health research to determine trends and develop evidence-based solutions to improve current standards of care, cost effectiveness of treatment, and health outcomes. 

The programme evaluation process at SingHealth RHS is designed to help project stakeholders better understand the impact of these programmes on patient care, as well as to continually improve on the programmes to achieve better outcomes.

SingHealth PULSES Centre Grant

The SingHealth Population-based, Unified, Learning System for Enhanced and Sustainable Health (PULSES) Centre Grant is funded by the National Medical Research Council to build population health research capabilities and foster multidisciplinary collaborations to address the unmet healthcare needs of our population.

Our four research themes are aligned with the Ministry of Health's Beyond Healthcare 2020 strategy.    


1.      Population Segmentation

Population segmentation serves to facilitate the efficient allocation of services and resources to meet the needs of our rapidly aging population.   This research theme aims to develop a parsimonious and actionable population segmentation framework relevant to Singaporeans' biopsychosocial needs that can be applied at different geographical levels.

Research in this theme focuses on:

  • Adopting various approaches in population segmentation,
  • Identifying optimal indicators and outcomes of population segmentation, and
  • Designing and trialling targeted interventions for well-defined and actionable segments


2.      Diabetes

The prevalence of diabetes is steadily increasing, in part due to the obesity epidemic and our aging population. Undiagnosed and poorly-controlled diabetes can lead to complications and compromised quality of life. Early screening and detection can significantly improve these outcomes.

Research in this theme focuses on:

  • Improving outreach efforts to make screening more accessible,
  • Empowering self-management through asset-based community development and/or technology-enabled platforms, and
  • Enhancing treatment of diabetes and complications.


3.      Patients with complex needs

Patients with multiple comorbidities often have complex biomedical, psychological and social needs that interact and affect their health outcomes.  To address these needs, health and social care providers require data to deliver interventions that are appropriate for these patients.

Research in this theme focuses on:

  • Identifying patients with complex needs,
  • Understanding the determinants of health,
  • Innovating and evaluating new interventions and models of care, and
  • Improving self-management through technology-enabled platforms.


4.      Pre-frailty and Frailty

Frailty is associated with significantly increased risk of poor physical health, hospitalisation, nursing home care and mortality.  Onset of frailty and related conditions among at-risk populations can be delayed through programmes that incorporate social, medical and lifestyle interventions.

Research in this theme focuses on:

  • Early detection of pre-frailty and frailty in the community,
  • Prognosticating frailty trajectories,
  • Understanding the determinants of frailty,
  • Identifying candidate biomarkers, and
  • Co-creating frailty interventions in the community.

For enquiries, please email