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Clin Asst Prof Tay Tunn Ren

Clin Asst Prof


Senior Consultant

Changi General Hospital

Specialty: Respiratory and Critical Care Medicine

Sub-specialties: Pulmonary Medicine, Critical Care Medicine, Asthma

Clinical Appointments

  • Senior Consultant Respiratory & Critical Care Medicine Changi General HospitalChangi General Hospital


Dr Tay Tunn Ren is a Senior Consultant in the Department of Respiratory & Critical Care Medicine at Changi General Hospital (CGH). She received her medical degree from the National University of Singapore (NUS) in 2006 and completed her specialist training in respiratory medicine and intensive care medicine in 2013 and 2015 respectively.

Dr Tay has an interest in asthma and runs the difficult asthma clinic in CGH.


  • Fellowship in Asthma and Allergy (the Alfred Hospital, Melbourne, Australia)
  • Specialist Accreditation in Intensive Care Medicine (Singapore)
  • Specialist Accreditation in Respiratory Medicine (Singapore)
  • MRCP (UK)
  • MBBS (Singapore)

Professional Appointments and Committee Memberships

  • Clinical Assistant Professor - Duke-NUS
  • Member - FAMS
  • Senior Clinical Lecturer - NUS Yong Loo Lin School of Medicine


  • Star Award, Singapore Health Quality Service Awards 2022
  • Outstanding Faculty Award, SingHealth RISE Awards 2019
  • CGH Caring Award 2014 – Silver
  • Global Abstract Award (Best abstract from Singapore). ACCP Chest Conference 2012
  • Recognition Award for Outstanding Abstract by the Respiratory Care NetWork. ACCP Chest Conference 2012
  • Best Oral Presentation (Singapore Thoracic Society Pulmonary Fellow Presentation Challenge), 2011

Research Interests

  • Asthma


  • Tunn Ren Tay, Job F M van Boven, Amy Chan, Mark Hew. Electronic Inhaler Monitoring for Chronic Airway Disease: Development and Application of a Multidimensional Efficacy Framework. J Allergy Clin Immunol Pract 2021 Dec 13;S2213-2198(21)01364-7. doi: 10.1016/j.jaip.2021.11.027.
  • Wui Mei Chew, Chee Hong Loh, Aditi Jalali, Grace Shi En Fong, Loshini Senthil Kumar, Rachel Hui Zhen Sim, Russell Pinxue Tan, Sunil Ravinder Gill, Trilene Ruiting Liang, Jansen Meng Kwang Koh, Tunn Ren Tay. A risk prediction score to identify patients at low risk for COVID-19 infection. Singapore Med J. 2021 Mar 12. doi: 10.11622/smedj.2021019.
  • Joy Lee, Eve Denton, Ryan Hoy, Tunn Ren Tay, Janet Bondarenko, Fiona Hore-Lacy, Naghmeh Radhakrishna, Robyn E O'Hehir, Eli Dabscheck, Michael J Abramson, Mark Hew. Paradoxical Vocal Fold Motion in Difficult Asthma Is Associated with Dysfunctional Breathing and Preserved Lung Function. J Allergy Clin Immunol Pract. Jul-Aug 2020;8(7):2256-2262
  • Ling Eng Tan, Wan Hui Gloria Tan, Mohamed Ismail Abdul Aziz, Mariko Siyue Koh, Tunn Ren Tay, Fiona Pearce, Kwong Ng. Assessing the cost-effectiveness of mepolizumab as add-on therapy to standard of care for severe eosinophilic asthma in Singapore. J Asthma. 2020 Nov 10;1-11
  • Denton E, Lee J, Tay T, Radhakrishna N, Hore-Lacy F, Mackay A, Hoy R, Dabscheck E, O'Hehir RE, Hew M. Systematic Assessment for Difficult and Severe Asthma Improves Outcomes and Halves Oral Corticosteroid Burden Independent of Monoclonal Biologic Use. J Allergy Clin Immunol Pract. 2020. pii: S2213-2198(20)30037-4. doi: 10.1016/j.jaip.2019.12.037.
  • Tay TR, Choo XN, Yii A, Chung KF, Chan YH, Wong HS, Chan A, Tee A, Koh MS. Asthma phenotypes in a multi-ethnic Asian cohort. Respir Med. 2019 Oct;157:42-48. doi: 10.1016/j.rmed.2019.08.016.
  • Tay T, Choo X, Ihsan R, Toh HP, Wong HS, Tee A. Characteristics of non-smoking adult asthma patients with chronic airflow limitation. J Asthma. 2017 Dec;54(10):1026-1032
  • Tay TR, Hew M. Comorbid "treatable traits" in difficult asthma: Current evidence and clinical evaluation. Allergy. 2017 Nov 27. doi: 10.1111/all.13370. [Epub ahead of print]
  • Tay TR, Lee J, Radhakrishna N, Hore-Lacy F, Stirling R, Hoy R, Dabscheck E, O'Hehir R, Hew M. A Structured Approach to Specialist-referred Difficult Asthma Patients Improves Control of Comorbidities and Enhances Asthma Outcomes. J Allergy Clin Immunol Pract. 2017 Jul - Aug;5(4):956-964
  • Tay TR, Wong HS, Ihsan R, Toh HP, Choo X, Tee AK. Comparison of the Proportion and Healthcare Utilisation of Adult Patients with Uncontrolled Severe Asthma versus Non-Severe Asthma Seen in a Southeast Asian Hospital-Based Respiratory Specialist Clinic. Ann Acad Med Singapore. 2017 Jun;46(6):217-228.
  • Radhakrishna N, Tay TR, Hore-Lacy F, Stirling R, Hoy R, Dabscheck E, Hew M. Validated questionnaires heighten detection of difficult asthma comorbidities. J Asthma. 2017 Apr;54(3):294-299
  • Hew M, Tay TR. The efficacy of bedside chest ultrasound: from accuracy to outcomes. Eur Respir Rev. 2016 Sep;25(141):230-46.
  • Tay TR, Hoy R, Richards AL, Paddle P, Hew M. Inhaled Mannitol as a Laryngeal and Bronchial Provocation Test. J Voice. 2017 Mar;31(2):247.e19-247.e23. doi: 10.1016/j.jvoice.2016.08.003. Epub 2016 Aug 25.
  • Radhakrishna N, Tay TR, Hore-Lacy F, Hoy R, Dabscheck E, Hew M. Profile of difficult to treat asthma patients referred for systematic assessment. Respir Med. 2016 Aug;117:166-73
  • Tay TR, Bosco J, Gillman A, Aumann H, Stirling R, O’Hehir R, Hew M. Co-existing Atopic Conditions Influence the Likelihood of Allergic Bronchopulmonary Aspergillosis in Asthma. Ann Allergy Asthma Immunol. 2016 Jul;117(1):29-32
  • Tay TR, Bosco J, Aumann H, O’Hehir R, Hew M. Elevated Total Serum IgE (>1000 IU/ml): Implications? Intern Med J. 2016 Jul;46(7):846-9
  • Tay TR, Abramson MJ, Hew M. Closing the million patient gap of uncontrolled asthma. Med J Aust. 2016 Apr 4;204(6):216-7.
  • Tay TR, Radhakrishna N, Hore-Lacey F, Smith C, Hoy R, Dabscheck E, Hew M. Comorbidities in Difficult Asthma are Independent Risk Factors for Frequent Exacerbations, Poor Control, and Diminished Quality of Life. Respirology. 2016 Nov;21(8):1384-1390. doi: 10.1111/resp.12838. Epub 2016 Jul 1.
  • Mok Y, Tan TY, Tay TR, Wong HS, Tiew PY, Kam JW, Siao C. Do we need transbronchial lung biopsy if we have bronchoalveolar lavage Xpert® MTB/RIF? Int J Tuberc Lung Dis. 2016 May;20(5):619-24.
  • Tay TR, Tee A. Factors affecting pleural fluid adenosine deaminase level and the implication on the diagnosis of tuberculous pleural effusion: a retrospective cohort study. BMC Infect Dis. 2013 Nov 16;13:546. doi: 10.1186/1471-2334-13-546

Research Trials