Dr Ivy Ho received her Ph.D. from the National Cancer Centre in the field of viral gene therapy for glioma. She continued her postdoctoral training working on understanding the mechanism of mesenchymal stem cell migration and their role in cancer therapy. Her findings suggested a role of mesenchymal stem cells in modulating the tumor stroma microenvironment that inhibited glioma progression.
She is currently a Principal Investigator and heads the Molecular Neurotherapeutics Laboratory at the National Neuroscience Institute. Her long time interest in brain tumor therapy has led her to focus on understanding the intrinsic and microenvironmental factors that influence glioma therapy. In particular, the lab is investigating how reciprocal communication between glioma cells and the immune microenvironment influence glioma invasion and mesenchymal transition.
Another area research work involves understanding the role of the NF1 tumor suppressor gene in brain tumor cells invasion and neuroblastoma metastasis.
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