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Adj Assoc Prof Eva Fenwick

Adj Assoc Prof Fenwick Eva

BA (Hons), MA, PhD

Academic Appointments

  • Adjunct Associate Professor SingHealth Duke-NUS Ophthalmology & Visual Sciences Academic Clinical Programme


​Dr Eva Fenwick is a Senior Clinical Research Fellow in the Population Health Research Unit at the Singapore Eye Research Institute (SERI). She also holds a joint appointment as an Adjunct Associate Professor at the Duke-NUS Medical School. Dr Fenwick has a keen interest in developing and validating ophthalmic quality of life item banks and computerized adaptive testing (CAT) systems using psychometric methods to help to better understand the impact of eye conditions, vision impairment and treatments from the patient’s perspective. Her current work aims to evaluate the feasibility, effectiveness and patient-centred impact of implementing quality of life ophthalmic CATs in tertiary eye institutes around the world. Dr Fenwick has published widely in patient-centred outcomes research and modern psychometric theory as well as other areas of health services research including health literacy, risk factors associated with development and progression of eye diseases, and the effectiveness of behavioural interventions to improve patient outcomes in ophthalmology.


  • PhD (2014)
  • MA (2008)
  • BA (Hons) (2004)

Professional Appointments and Committee Memberships

  • Honorary Clinical Researcher, Royal Victorian Eye and Ear Hospital (2012 - Current)
  • Member, Association for Research in Vision and Ophthalmology (ARVO) (2010 - Current)
  • Member, Eureka Monsoon Translational Medicine network (2018)
  • Member, Health Services Research Association of Australia and New Zealand (HSRAANZ) (2014 - 2015)
  • Member, Steering Committee, The Vision Initiative – Vision 2020 Australia (2013 - 2014)
  • Advisory Committee Member, Post-graduate Student Progress Reviews, CERA (2012 - 2015)
  • Associate Faculty Member, Faculty of 1000 Post-publication Peer Review (2010 - 2012)


  • Conference Travel Grant, ARVO-Asia 2017 (2016)
  • “The CERA Outstanding Contribution of a Student Award for the student who has made an outstanding contribution to CERA overall in 2010/11”, CERA (2011)
  • The prestigious Henry James Williams Scholarship, University of Melbourne (2010)
  • Australian Postgraduate Award Scholarship, University of Melbourne for Masters of Arts (by research) (2005)
  • The Dwight’s prize in Linguistics, Outstanding Honours Results, The University of Melbourne (2004)

Research Interests

  • Patient-reported outcomes (e.g. quality of life and health literacy)
  • Modern psychometric methods
  • Item banking and computerized adaptive testing
  • Epidemiology of eye diseases
  • Behavioural interventions to improve patient outcomes


  1. EK Fenwick, EPX Lee, REK Man, KC Ho, RP Najjar, D Milea, KYC Teo, ACS Tan, LS Yen, IYS Yeo, GSW Tan, R Mathur, TY Wong, CMG Cheung, EL Lamoureux. Identifying the Content for an Item Bank and Computerized Adaptive Testing System to Measure the Impact of Age-related Macular Degeneration on Health-related Quality of Life. Qual Life Res. 2021. Epub ahead of print.
  2. A Aravindhan, ATL Gan, EPX Lee, P Gupta, REK Man, KC Ho, SC Sung, CY Cheng, LM Lin, TH Khoon, TY Wong, EK Fenwick*, EL Lamoureux* (co-senior authors). Knowledge, Attitudes, and Practice towards COVID-19 among Multi-ethnic Elderly Asian Residents in Singapore: A Mixed Methods Study. Singapore Med J. 2021. Epub ahead of print.
  3. EK Fenwick, S Ozdemir, REK Man, D Baid, HM Htoon, ATL Gan, ML Tey, AT Aw, B Mani, ME Nongpiur, E Finkelstein, CS Tey, HJT Soon, C Sabanayagam, CCA Sng, TY Wong, R Husain, S Perera, K Lun, T Aung, EL Lamoureux. Development and Validation of a Preference-based Glaucoma Utility Instrument Using Discrete Choice Experiment. JAMA Ophthalmol. 2021. Epub ahead of print.
  4. EK Fenwick, ATL Gan, REK Man, P Gupta, C Sabanayagam, CY Cheng, CLH Chen, CY Cheung, KH Wong, N Venketasubramanian, X Xu, S Hilal, EJY Chong, YC Tham, TY Wong, EL Lamoureux. Vision, Vision-specific Functioning and Mobility, and their Relationship with Clinically-assessed Cognitive Impairment. Age and Ageing. [Accepted 17 Nov 2020].
  5. EK Fenwick, Man REK, ATL Gan, A Aravindhan, CS Tey, HJT Soon, DSW Ting, SIY Yeo, SY Lee, G Tan, TY Wong, EL Lamoureux. Validation of a New Diabetic Retinopathy Knowledge and Attitudes Questionnaire in People with Diabetic Retinopathy and Diabetic Macular Edema. TVST. 2020. 9(10): 32.
  6. EK Fenwick, J Barnard, A Gan, BS Loe, J Khadka, K Pesudovs, REK Man, SY Lee, G Tan, TY Wong, EL Lamoureux. Computerized Adaptive Tests: Efficient and Precise Assessment of the Patient-centered Impact of Diabetic Retinopathy. TVST. 2020. 9(7): 3.
  7. EK Fenwick, REK Man, P Ramulu, T Aung, EL Lamoureux. Beyond Intraocular Pressure: Optimizing Patient-reported Outcomes in Glaucoma. Prog Retin Eye Res. 2019. 76:100801.
  8. EK Fenwick, BS Loe, J Khadka, REK Man, G Rees, EL Lamoureux. Optimizing Measurement of Vision-related Quality of Life: A Computerized Adaptive Test for the Impact of Vision Impairment Questionnaire (IVI-CAT). Qual Life Res. 2019. 29(3): 765-774.
  9. GS Ang*, EK Fenwick*, M Constantinou, A Gan, REK Man, R Casson, E Finkelstein, I Goldberg, P Healey, K Pesudovs, J Xie, R Macintosh, J Crowston^, EL Lamoureux^. Selective Laser Trabeculoplasty versus Topical Medication as Initial Treatment for Glaucoma: Results of the Glaucoma Initial Treatment Study Multi-centre Randomised Controlled Trial. Br J Ophthalmol. 2020. 104(6):813-821. *Joint 1st authors.
  10. EK Fenwick, N Bansback, J Ratcliffe, L Burgiss, TY Wong, EL Lamoureux. Validation of a Novel Diabetic Retinopathy Utility Index using Discrete Choice Experiments. Br J Ophthalmol. 2020. 104(2):188-193.
  11. EK Fenwick, REK Man, N Kumari, C Wong, ATL Gan, A Aravindhan, P Gupta, JJ Wang, P Mitchell, TY Wong, CY Cheng, EL Lamoureux. Beyond Vision Loss: The Independent Impact of Diabetic Retinopathy on Vision-related Quality of Life in a Chinese Singaporean Population. Br J Ophthalmol. 2019. 103(9): 1314-19.
  12. EK Fenwick, J Khadka, K Pesudovs, G Rees, TY Wong, EL Lamoureux. Diabetic Retinopathy and Diabetic Macular Edema Quality-of-life Item Banks: Development and Initial Evaluation using Computerized Adaptive Testing. Invest Ophthalmol Vis Sci. 2017. 58(14): 6379-6387.
  13. EK Fenwick, CHL Grand, REK Man, G Rees, J Khadka, K Pesudovs, EL Lamoureux. Inter-relationship between Visual Symptoms, Activity Limitation and Psychological Functioning in Patients with Diabetic Retinopathy. Br J Ophthalmol. 2018. 102(7): 948-953. 
  14. EK Fenwick, CMG Cheung, ATL Tan, G Tan, SY Lee, D Wong, I Yeo, R Mathur, TY Wong, EL Lamoureux. Change in Vision-related Quality of Life and Influencing Factors in Asians Receiving Treatment for Neovascular Age-related Macular Degeneration. Br J Ophthalmol. 2018. 102(3): 377-382.
  15. EK Fenwick, REK Man, SP Tan, CY Cheng, TY Wong, EL Lamoureux. Ethnic Differences in the Impact of Age Related Macular Degeneration on Vision Specific Function. JAMA Ophthalmol. 2017. 135(5): 469-476.
  16. EK Fenwick, PG Ong, REK Man, C Sabanayagam, CY Cheng, TY Wong, P Gupta, EL Lamoureux. Association of Changes in Visual Acuity on Vision-specific Functioning in the Singapore Malay Eye Study. JAMA Ophthalmol. 2016. 134(11): 1299-1305.
  17. EK Fenwick, G Rees, J Keeffe, TY Wong, EL Lamoureux. Reducing Respondent Burden: Validation of the Brief Impact of Vision Impairment Questionnaire. Qual Life Res. 2017. 26(2): 479-488.
  18. EK Fenwick, PG Ong, REK Man, C Sabanayagam, CY Cheng, TY Wong, EL Lamoureux. Vision Impairment and Major Eye Diseases Reduce Vision-specific Emotional Well-being in a Chinese Population. Br J Ophthalmol. 2017. 101(5): 686-690.
  19. EK Fenwick, PG Ong, REK Man, C Sabanayagam, CY Cheng, TY Wong, EL Lamoureux. Association of Vision Impairment and Major Eye Diseases with Mobility and Independence in a Chinese Population. JAMA Ophthalmol. 2016. 134(10): 1087-93.
  20. EK Fenwick, EL Lamoureux, RP Finger, L Lim, G Rees. Patients’ Causal Beliefs about Diabetic Retinopathy. Optom Vis Sci. 2013. 90(8): 874-82.

Research Trials

  • ​Revolutionising the Assessment of Quality of Life in Diabetes Using Item Banking and Computerised Adaptive Testing Systems: DiabCAT (2021 - present)
  • Translational Asian Age-Related Macular Degeneration Program (TAAP) – Theme 5: Quality of Life: Improving Patient-Centered Outcomes in AMD and PCV – Phase 1 (2018 - present)
  • Optimizing the Assessment of Quality of Life in Glaucoma Using Item Bank and Computer Adaptive Testing Systems (2018 – present)
  • An Intensive, Practical, and Personalized Care Planning to Improve Glycemic Control, Clinical, Ocular, And Patient Centred Outcomes in Poorly Controlled Patients with Diabetic Retinopathy (2018 - present)
  • Development of a novel utility measure using discrete choice experiments to assess the impact of glaucoma treatments from the patient's perspective (2017 - present)
  • The Singapore diabetes complications study: closing the screening-referral uptake loop for diabetic retinopathy, nephropathy, and foot complications (2016 - present)
  • The Clinical and Economic Effectiveness of Extending Diabetic Eye Screening in Singapore (2016 - 2021)
  • Validation of a comprehensive item bank and computer adaptive testing (CAT) system to assess the impact of diabetic retinopathy (DR) and diabetic macular edema (DME) on patient's QoL in Singapore: The Singapore 'RetBank' trial (2016 - 2018)