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Assoc Prof Edward Choke Tieng Chek

Assoc Prof Edward Choke

MBBS (Sydney), PhD (London), FRCS (England)

Head ＆ Senior Consultant

Sengkang General Hospital

Specialty: General Surgery

Conditions Treated by this Doctor:
Acute and Chronic Aortic Dissections, Aortic Aneurysms (Thoracic, Thoracoabdominal and Abdominal), Arteriovenous Malformation (AVM), Carotid Aneurysms, Carotid Atherosclerotic Disease and Stroke Prevention, Carotid Body Tumours, Deep Vein Thrombosis, Deep Vein Thrombosis, Diabetic Foot Disease, Dialysis access for hemodialysis and peritoneal dialysis, Holistic Care in Peripheral Arterial Disease (HOPE), May Thurner Syndrome, Mesenteric and Renovascular Disease, Peripheral and Visceral Aneurysms, Peripheral Vascular Disease, Popliteal Artery Entrapment Syndrome (PAES), Thoracic Outlet Syndrome, Varicose Veins, Vascular Graft Infections, Vascular Trauma, Vena Caval Filters, Venous Ulcers.

Clinical Appointments

  • Senior Consultant Division of Surgery ＆ Surgical Oncology National Cancer Centre SingaporeNational Cancer Centre Singapore
  • Service Chief SingHealth Duke-NUS Vascular Centre
  • Senior Consultant Department of General Surgery Sengkang General HospitalSengkang General Hospital
  • Head ＆ Senior Consultant Vascular and Endovascular Service Sengkang General HospitalSengkang General Hospital

Profile

Dr Edward Choke is presently a Senior Consultant Vascular and Endovascular Surgeon at Sengkang General Hospital. He graduated with first class honours MBBS from the University of Sydney and undertook specialist training in General and Vascular Surgery in Oxford between 2006 and 2010. In 2010 he was appointed the Clinical Lecturer/Specialist Registrar at the vascular unit in Leicester Royal Infirmary. He received training in complex tertiary level vascular and endovascular surgery, including complex abdominal and thoracic aortic aneurysm repairs (open, endovascular or hybrid techniques) and complex carotid surgery. He was one of three UK trainees in 2012 to receive the competitive British Society of Endovascular Therapy Endovascular Fellowship which advanced his skills in peripheral angioplasties and hybrid techniques for complex multilevel occlusive or stenotic disease.

Besides clinical excellence, he is also passionate about clinical and basic science research as part of improving the quality of care for patients. He undertook award winning scientific research between 2003 and 2006 at St George's Vascular Institute, leading to a PhD from the University of London. He was the recipient of the American Heart Association Merit Award for Junior Investigators, the UK Medical Research Society Prize and the International Meeting for AAA Prize. He is the principal investigator of research grants from the British Heart Foundation, Wellcome Trust, Academy of Medical Sciences and Circulation Foundation (George Davies Visionary Award). He has over 100 publications in peer reviewed international journals including high impact journals such as European Heart Journal, Circulation, ATVB, the British Journal of Surgery. He has written 5 book chapters in vascular surgery and is regularly invited to review manuscripts from international journals. He is also regularly invited to speak at key international conferences including the Charing Cross 35th Vascular Symposium in London. He is a keen teacher and am a faculty member of DUKE-NUS and NUS-YLL School of Medicine and the University of Edinburgh/Royal College of Surgeons of Edinburgh ChM in Vascular and Endovascular Surgery.

Education

  • MBBS (Sydney)
  • PhD (London)
  • FRCS (England)

Professional Appointments and Committee Memberships

  • Clinical Associate Professor, SingHealth Duke-NUS Medical School
  • Clinical Senior Lecturer, Yong Loo Lin School of Medicine, National University of Singapore
  • Vice President, Singapore Society of Endovascular and Vascular Surgery
  • Education Chair, Society of Dialysis Access Specialists
  • Member, Vascular Society of Great Britain and Ireland
  • Faculty, SingHealth Residency Training Programme for General Surgery and Cardiothoracic Surgery

Awards

  • Sol Cohen Founders Prize, Vascular Society GBI Scientific Meeting, 2012
  • Raymond Limet Prize, International Meeting for Aortic Diseases, 2012
  • British Society of Endovascular Therapy Prize, BSET Meeting, 2012
  • Foundation for AAA Research Prize, International Meeting for Aortic Diseases, 2008
  • Finalist, Michael Davies Young Investigator Award, British Atherosclerosis Society, 2008
  • Finalist, Medical Insurance Agency Prize, Royal Society of Medicine, Royal Society of Medicine Conference, 2007
  • MRS Prize, Medical Research Society, 2007
  • South West Thames Presentation Prize, SWT Vascular Group Meeting, 2006
  • ATVB Merit Award for Young Investigators, American Heart Association Scientific Sessions, 2006
  • Lord Taylor Prize, St George's Scientific Conference, 2005
  • South West Thames Presentation Prize, SWT Vascular Group Meeting, 2005

Research Interests

Publications

Associate Professor Choke has published more than 100 articles in peer-reviewed journals and books.  He is currently leading major international multicentre trials such as the FUTURE SFA and FUTURE BTK randomised controlled trials, the SingHealth Vascular Registry, the HOPE project (Holistic Care in Peripheral Vascular Disease), and the Sirolimus drug coated balloon Registry (X-TOSI Study).  He continues to be active in clinical and translational research projects.

Selected publications (100+)

  1. Choke E, Thompson M. Endoleak after endovascular aneurysm repair: current concepts. J Cardiovasc Surg (Torino). 2004 Aug;45(4):349-66.
  2. Choke E, Cockerill G, Wilson WR, Sayed S, Dawson J, Loftus I, Thompson MM. A review of biological factors implicated in abdominal aortic aneurysm rupture. Eur J Vasc Endovasc Surg. 2005 Sep;30(3):227-44.
  3. Sayed S, Choke E, Helme S, Dawson J, Morgan R, Belli A, Loosemore T, Thompson MM. Endovascular stent graft repair of mycotic aneurysms of the thoracic aorta. J Cardiovasc Surg (Torino). 2005 Apr;46(2):155-61.
  4. Ashoke R, Brown LC, Rodway A, Choke E, Thompson MM, Greenhalgh RM, Powell JT. Color duplex ultrasonography is insensitive for the detection of endoleak after aortic endografting: a systematic review. J Endovasc Ther. 2005 Jun;12(3):297-305.
  5. Dawson J, Choke E, Sayed S, Cockerill G, Loftus I, Thompson MM. Pharmacotherapy of abdominal aortic aneurysms. Curr Vasc Pharmacol. 2006 Apr;4(2):129-49.
  6. Choke E, Thompson MM, Dawson J, Wilson WR, Sayed S, Loftus IM, Cockerill GW. Abdominal aortic aneurysm rupture is associated with increased medial neovascularization and overexpression of proangiogenic cytokines. Arterioscler Thromb Vasc Biol. 2006 Sep;26(9):2077-82.
  7. Choke E, Munneke G, Morgan R, Belli AM, Loftus I, McFarland R, Loosemore T, Thompson MM. Outcomes of endovascular abdominal aortic aneurysm repair in patients with hostile neck anatomy. Cardiovasc Intervent Radiol. 2006 Nov-Dec;29(6):975-80.
  8. Wilson WR, Choke E, Dawson J, Loftus IM, Thompson MM. Contemporary management of the infra-renal abdominal aortic aneurysm. Surgeon. 2006 Dec;4(6):363-71
  9. Dawson J, Vig S, Choke E, Blundell J, Horne G, Downham C, Loftus I, Thompson MM. Medical optimisation can reduce morbidity and mortality associated with elective aortic aneurysm repair. Eur J Vasc Endovasc Surg. 2007 Jan;33(1):100-4.
  10. Choke E, Cockerill GW, Dawson J, Chung YL, Griffiths J, Wilson RW, Loftus IM, Thompson MM. Hypoxia at the site of abdominal aortic aneurysm rupture is not associated with increased lactate. Ann N Y Acad Sci. 2006 Nov;1085:306-10.
  11. Choke E, Thompson MM, Jones A, Torsney E, Dawson J, Laing K, Nasr H, Loftus IM, Cockerill GW. Gene expression profile of abdominal aortic aneurysm rupture. Ann N Y Acad Sci. 2006 Nov;1085:311-4.
  12. Choke E, Cockerill GW, Dawson J, Wilson RW, Jones A, Loftus IM, Thompson MM. Increased angiogenesis at the site of abdominal aortic aneurysm rupture. Ann N Y Acad Sci. 2006 Nov;1085:315-9.
  13. Dawson J, Cockerill G, Choke E, Loftus I, Thompson MM. Aortic aneurysms as a source of circulating interleukin-6. Ann N Y Acad Sci. 2006 Nov;1085:320-3.
  14. Dawson J, Cockerill G, Choke E, Loftus I, Thompson MM. Circulating cytokines in patients with abdominal aortic aneurysms. Ann N Y Acad Sci. 2006 Nov;1085:324-6.
  15. Dawson J, Tooze J, Cockerill G, Choke E, Loftus I, Thompson MM. Endothelial progenitor cells and abdominal aortic aneurysms. Ann N Y Acad Sci. 2006 Nov;1085:327-30.
  16. Dawson J, Cockerill GW, Choke E, Belli AM, Loftus I, Thompson MM. Aortic aneurysms secrete interleukin-6 into the circulation. J Vasc Surg. 2007 Feb;45(2):350-6.
  17. Choke E, Munneke G, Morgan R, Belli AM, Dawson J, Loftus IM, McFarland R, Loosemore T, Thompson MM. Visceral and Renal Artery Complications of Suprarenal Fixation during Endovascular Aneurysm Repair. Cardiovasc Intervent Radiol. 2007 Jul;30(4):619-627.
  18. Wilson WR, Anderton M, Choke E, Dawson J, Loftus IM, Thompson MM. Elevated Plasma MMP1 and MMP9 are Associated with Abdominal Aortic Aneurysm Rupture. Eur J Vasc Endovasc Surg. 2008 May;35(5):580-4.
  19. Bharwani N, Raja J, Choke E, Belli AM, Thompson MM, Morgan RA, Munneke G. Is Internal Iliac Artery Embolization Essential Prior to Endovascular Repair of Aortoiliac Aneurysms? Cardiovasc Intervent Radiol 2008 May-Jun;31(3):504-8
  20. E Choke, GW Cockerill, J Dawson, F Howe, K Laing, IM Loftus, MM Thompson. The role of angiogenesis in abdominal aortic aneurysm rupture. Atherosclerosis 2008;199 (2), 463-464
  21. Dawson J, Choke E, Cockerill G, Loftus I, Thompson M. The long-term effects of open and endovascular aneurysm repair on circulating interleukin-6. Eur J Vasc Endovasc Surg 2009 Jan;37(1):43-5.
  22. Choke E, GW Cockerill, K Laing, J Dawson, WRW Wilson, IM Loftus, MM Thompson. Whole genome expression profiling reveals a role for immune and inflammatory response in abdominal aortic aneurysm rupture. Eur J Vasc Endovasc Surg. 2009 Mar;37(3):305-10.
  23. Wilson WR, Choke E, Dawson J, Loftus IM, Thompson MM. Plasma matrix metalloproteinase levels do not predict tissue levels in abdominal aortic aneurysms suitable for elective repair. Vascular. 2008 Sep-Oct;16(5):248-52.
  24. Choke E, Cockerill GW, Dawson J, Howe F, Wilson WRW, Loftus I, Thompson MM. Vascular endothelial growth factor enhances angiotensin-II induced aneurysm formation in apolipoprotein E-deficient mice. J Vasc Surg. 2010 Jul;52(1):159-166
  25. Choke E, McCarthy M. Hybrid procedures in vascular surgery: converging technique to improve results. J Cardiovasc Surg. 2010 Dec;51(6):857-9.
  26. Dawson JA, Choke E, Loftus IM, Cockerill GW, Thompson MM . A Randomised Placebo-controlled Double-blind Trial to Evaluate Lipid-lowering Pharmacotherapy on Proteolysis and Inflammation in Abdominal Aortic Aneurysms. Eur J Vasc Endovasc Surg. 2011 Jan;41(1):28-35
  27. JA Stephenson, S Panteleimonitis, E Choke, M Dennis, M Glasby. Endovascular treatment of a giant aneurysm of the maxillary artery. Case reports in vascular medicine 2011;2011:818241.
  28. Choke E, Vijaynagar B, Thompson J, Nasim A, Bown MJ, Sayers RD. Changing epidemiology of abdominal aortic aneurysms in England and Wales: older and more benign? Circulation. 2012 Apr 3;125(13):1617-25
  29. Karthikesalingam A, Thrumurthy SG, Jackson D, Choke E, Sayers RD, Loftus IM, Thompson MM, Holt PJ.Current Evidence Is Insufficient to Define an Optimal Threshold for Intervention in Isolated Type II Endoleak After Endovascular Aneurysm Repair. J Endovasc Ther. 2012 Apr;19(2):200-8.
  30. Ehsan S, Ball G, Choke E, Molyneux KM, London NJM, Herbert KE, Barratt J, Sayers RD, Bown MJ.Disease specific biomarkers of Abdominal Aortic Aneurysms detected by Surface Enhanced Laser Desorption Ionization Time of Flight Mass Spectrometry. Eur J Vasc Endovasc Surg. 2012 Jul;44(1):52-4
  31. Wild JB, Stather PW, Sylvius N, Choke E, Sayers RD, Bown MJ. LRP1 and Abdominal Aortic Aneurysms. Eur J Vasc Endovasc Surg 2012 Aug;44(2):127-32
  32. G. Ambler, J.R. Boyle, C. Cousins, P.D. Hayes, T. Metha, T.C. See, K. Varty, A. Winterbottom, D.J. Adam, A.W. Bradbury, M.J. Clarke, R. Jackson, J.D. Rose, A. Sharif, V. Wealleans, R. Williams, L. Wilson, M.G. Wyatt, I. Ahmed, R.E. Bell, T.W. Carrell, P. Gkoutzios, T. Sabharwal, R. Salter, M. Waltham, C. Bicknell, P. Bourke, N. Cheshire, I. Franklin, A. James, M.P. Jenkins, M.R. Tyrrell, C.J. Wilkins, M. Bown, Choke E, M. McCarthy, R. Sayers, A. Tamberaja, F. Farquharson, F. Serracino-Inglott, M. Davis, G. Hamilton, A. Brennan, R. Canavati, R.K. Fisher, R.G. McWilliams, J.B. Naik, S.R. Vallabhaneni, J. Hardman, S. Black, R. Hinchliffe, P. Holt, I.M. Loftus, T. Loosemore, R, Morgan, M.M. Thompson O. Agu, C. Bishop, D. Boardley, J. Cross, J. Hague, P.L. Harris, K. Ivancev, J. Raja, T. Richards, D. Simring A.C. Fisher, D. Smith, G.P. Copeland. Early Results of Fenestrated Endovascular Repair of Juxtarenal Aortic Aneurysms in the United Kingdom. Circulation. 2012 Jun 5;125(22):2707-15
  33. Gokani V, Fishwick G, Choke E, Bown MJ, Sayers RD. 'Trial of Lunderqvist wire': a useful adjunct to determining suitability for endovascular aneurysm repair (EVAR). EJVES Extra. Volume 24, Issue 4, October 2012, Pages e23-e24
  34. Stather PW, Wild JB, Sylvius N, Choke E, Sayers RD, Bown M. MicroRNAs associated with the pathways involved in the pathogenesis of Abdominal Aortic Aneurysms. Artery Research. Volume 7, Issue 1, March 2013, Pages 28-35
  35. Choke E, Lee K, McCarthy M, Nasim A, Naylor AR, Bown M, Sayers R. Risk Models for Mortality Following Elective Open and Endovascular Abdominal Aortic Aneurysm Repair: A Single Institution Experience. Eur J Vasc Endovasc Surg. 2012 Dec;44(6):549-54
  36. Stather P, Sayers RD, Cheah A, Wild BJ, Bown MJ, Choke E. Outcomes of Endovascular Aneurysm Repair in patients with Hostile Neck Anatomy. Eur J Vasc Endovasc Surg. 2012 Dec;44(6):556-61
  37. VJ Gokani, NG Fishwick, E Choke, MJ Bown, RD Sayers. 'Trial of stiff guidewire': A useful adjunct to determining suitability for endovascular aneurysm repair. EJVES Extra 2012;24 (4), e23-e24
  38. E Choke. Commentary on 'Factors Related to Postoperative Delirium in Patients with Lower Limb Ischaemia: A Prospective Cohort Study, Sasajima et al.' European Journal of Vascular and Endovascular Surgery 2012;44 (4), 416
  39. Wild JB, Stather PW, Biancari F, Choke E, Earnshaw JJ, Grant SW, Hafez H, Holdsworth R, Juvonen T, Lindholt J, McCollum C, Parvin S, Sayers RD, Bown MJ A multicentre observational study of the outcomes of screening detected sub-aneurysmal aortic dilatation. Eur J Vasc Endovasc Surg. 2013 Feb;45(2):128-34
  40. Stather PW, Sidloff D, Dattani N, Choke E, Bown MJ, Sayers RD. Systematic review and meta-analysis of the early and late outcomes of open and endovascular repair of abdominal aortic aneurysm. Br J Surg. 2013 Jun;100(7):863-72
  41. Sidloff D, Stather P, Bown M, Sayers RD, Choke E. Pioneering techniques in abdominal aortic surgery and endovascular aneurysm repair. Italian Journal of Vasc Surg and Endovascular Surg, 2013 June;20(2):41-7
  42. Vijaynagar B, Bown MJ, Sayers RD, Choke E. Potential role for anti-angiogenic therapy in abdominal aortic aneurysms. Eur J Clin Invest. 2013 Jul;43(7):758-65
  43. Stather PW, Sidloff DA, Dattani N, Choke E, Bown MJ, Sayers RD. Authors' reply: Systematic review and meta-analysis of the early and late outcomes of open and endovascular repair of abdominal aortic aneurysm (Br J Surg 2013; 100: 863-872). Br J Surg. 2013 Oct;100(11):1541
  44. Wild B, Stather, P, Bown M, Sayers RD, Choke E. The effect of anticoagulation and antiplatelet therapy on the incidence of endoleaks and sac size expansions following endovascular aneurysm repair. Annals of Vascular Surgery, 2014 Apr;28(3):554-9
  45. Karthikesalingam A, Holt PJ, Vidal-Diez A, Choke E, Patterson BO, Thompson LJ, Ghatwary T, Bown MJ, Sayers RD, Thompson MM. Predicting aortic complications after endovascular aneurysm repair.Br J Surg. 2013 Sep;100(10):1302-11
  46. Stather P, Sylvius N, Dattani N, Choke E, Sayers RD, Bown MJ. Differential microRNA expression profiles in peripheral arterial disease. Circulation: Cardiovascular Genetics. 2013 Oct;6(5):490-7
  47. Karthikesalingam A, Cobb RJ, Khoury A, Choke EC, Sayers RD, Holt PJ, Thompson MM. The morphological applicability of a novel endovascular aneurysm sealing (EVAS) system (Nellix) in patients with abdominal aortic aneurysms. Eur J Vasc Endovasc Surg. 2013 Oct;46(4):440-5
  48. Sidloff DA, Stather PW, Choke E, Bown MJ, Sayers RD. Type II endoleak after endovascular aneurysm repair. Br J Surg. 2013 Sep;100(10):1262-70
  49. Stather PW, Sidloff D, Dattani N, Choke E, Bown MJ, Sayers RD. Authors' reply: systematic review and meta-analysis of the early and late outcomes of open and endovascular repair of abdominal aortic aneurysm (Br J Surg 2013; 100: 863-872). Br J Surg. 2013 Sep;100(10):1397-8.
  50. Stather PW, Wild JB, Sayers RD, Bown MJ, Choke E. Endovascular aortic aneurysm repair in patients with hostile neck anatomy. J Endovasc Ther. 2013 Oct;20(5):623-37
  51. Stather PW, Sidloff DA, Rhema IA, Choke E, Bown MJ, Sayers RD. A Review of Current Reporting of Abdominal Aortic Aneurysm Mortality and Prevalence in the Literature. Eur J Vasc Endovasc Surg. 2014 Mar;47(3):240-2
  52. Sidloff D, Stather P, Dattani N, Bown M, Thompson J, Sayers R, Choke E. Aneurysm Global Epidemiology Study: Public Health Measures can Further Reduce Abdominal Aortic Aneurysm Mortality. Circulation. 2014 Feb 18;129(7):747-53
  53. N Green, DA Sidloff, PW Stather, MJ Bown, RD Sayers, E Choke. Endoleak after endovascular aneurysm repair: Current status. Reviews in Vascular Medicine 2 (2), 43-47
  54. Sandford RM, Choke E, Bown MJ, Sayers RD. What is the Best Option for Elective Repair of an Abdominal Aortic Aneurysm in a Young Fit Patient? Eur J Vasc Endovasc Surg. 2014 Jan;47(1):13-8
  55. Sidloff DA, Stather PW, Choke E, Bown MJ, Sayers RD. Authors' reply: Type II endoleak after endovascular aneurysm repair (Br j surg 2013; 100: 1262-1270). Br J Surg. 2014 Jan;101(2):143.
  56. Sidloff DA, Stather PW, Choke E, Bown MJ, Sayers RD. A systematic review and meta-analysis of the association between markers of hemostasis and abdominal aortic aneurysm presence and size. J Vasc Surg. 2014 Feb;59(2):528-535
  57. Sidloff DA, Stather PW, Choke E, Bown MJ, Sayers RD. Authors' reply: Type II endoleak after endovascular aneurysm repair (Br J Surg 2013; 100: 1262-1270). Br J Surg. 2014 Feb;101(3):289.
  58. Sidloff DA, Gokani VJ, Stather PW, Choke E, Bown MJ, Sayers RD. National Vascular Registry Report on surgical outcomes and implications for vascular centres. Br J Surg. 2014 May;101(6):637-42
  59. Sidloff D, Stather P, Choke E, Bown M, Sayers R. Type II endoleaks: Low risk of rupture and high risk of treatment failure. Int J Surg. 2013 Oct;11(8):737
  60. Stather PW, Sidloff DA, Dattani N, Gokani VJ, Choke E, Sayers RD, Bown MJ. Meta-analysis and meta-regression analysis of biomarkers for abdominal aortic aneurysm. Br J Surg. 2014 Oct;101(11):1358-72
  61. Sidloff DA, Gokani V, Stather PW, Choke E, Bown MJ, Sayers RD. Type II Endoleak: Conservative Management Is a Safe Strategy. Eur J Vasc Endovasc Surg. 2014 Oct;48(4):391-9.
  62. The International AAA Screening Group, Björck M1, Bown MJ, Choke E, Earnshaw J, Flørenes T, Glover M, Kay M, Laukontaus S, Lees T, Lindholt J, Powell JT, van Rij A, Svensjö S, Wanhainen A. International Update on Screening for Abdominal Aortic Aneurysms: Issues and Opportunities. Eur J Vasc Endovasc Surg. 2014 Sep 18. pii: S1078-5884(14)00469-9.
  63. D A Sidloff, E Choke, P W Stather, MJ Bown, J Thompson, RD Sayers. Mortality from thoracic aortic diseases and associations with cardiovascular risk factor. Circulation 2014 Dec 23;130(25):2287-94
  64. Choke E. Commentary on 'Low post-operative mortality after surgery on patients with screening-detected abdominal aortic aneurysms: a Swedvasc registry study'. Eur J Vasc Endovasc Surg. 2014 Dec;48(6):657-8.
  65. 65.  Majid al-Rifaie M, Aber A, Sayers R, Choke E, Bown M. Deploying swarm intelligence in medical imaging. Bioinformatics and Biomedicine (BIBM) 2014, 14-21
  66. 66.  SWM Scott, S Bowrey, D Clarke, E Choke, MJ Bown, JP Thompson. Factors influencing short‐and long‐term mortality after lower limb amputation. Anaesthesia 69 (3), 249-258
  67. Sidloff DA, Gokani V, Stather PW, Choke E, Bown MJ, Sayers RD. Re: 'Type II Endoleak: Conservative Management Is a Safe Strategy'. Eur J Vasc Endovasc Surg. 2015 Jan;49(1):103-4
  68. Fitridge RA, Boult M, Mackillop C, De Loryn T, Barnes M, Cowled P, Thompson MM, Holt PJ, Karthikesalingam A, Sayers RD, Choke E, Boyle JR, Forbes TL, Novick TV. International trends in patient selection for elective endovascular aneurysm repair: sicker patients with safer anatomy leading to improved 1-year survival. Ann Vasc Surg. 2015 Feb;29(2):197-205.
  69. Gokani VJ, Sidloff D, Bath MF, Bown MJ, Sayers RD, Choke E. A retrospective study: Factors associated with the risk of abdominal aortic aneurysm rupture. Vascul Pharmacol. 2015 Feb-Mar;65-66:13-6.
  70. Choke E, Sayers R. Viewpoint: adaptation of vascular surgery in the interventional era. Heart. 2015 Mar;101(5):342-5.
  71. Stather PW, Sylvius N, Sidloff DA, Dattani N, Verissimo A, Wild JB, Butt HZ, Choke E, Sayers RD, Bown MJ. Identification of microRNAs associated with abdominal aortic aneurysms and peripheral arterial disease. Br J Surg. 2015 Jun;102(7):755-66.
  72. Bath MF, Gokani VJ, Sidloff DA, Jones LR, Choke E, Sayers RD, Bown MJ. Systematic review of cardiovascular disease and cardiovascular death in patients with a small abdominal aortic aneurysm. Br J Surg. 2015 Jul;102(8):866-72
  73. Dattani N, Wild J, Sidloff D, Fishwick G, Bown M, Choke E, Sayers R. Outcomes Following Limb Crossing in Endovascular Aneurysm Repairs. Vasc Endovascular Surg. 2015 Apr-May;49(3-4):52-7
  74. Stather PW, Rhema IA, Sidloff DA, Sayers RD, Bown MJ, Choke E. Short-Term Outcomes of Management of Endovascular Aneurysm Repair in Patients With Dilated Iliacs. Vasc Endovascular Surg. 2015 Apr-May;49(3-4):75-8
  75. Karthikesalingam A, Attallah O, Ma X, Bahia SS, Thompson L, Vidal-Diez A, Choke EC, Bown MJ, Sayers RD, Thompson MM, Holt PJ. An Artificial Neural Network Stratifies the Risks of Reintervention and Mortality after Endovascular Aneurysm Repair; a Retrospective Observational study. PLoS One. 2015 Jul 15;10(7)
  76. Salem MK, Butt HZ, Choke E, Moore D, West K, Robinson TG, Sayers RD, Naylor AR, Bown MJ. Gene and Protein Expression of Chemokine (C-C-Motif) Ligand 19 is Upregulated in Unstable Carotid Atherosclerotic Plaques. Eur J Vasc Endovasc Surg. 2016 Oct;52(4):427-436.
  77. E. Choke. Commentary on "Development of Collaterals to the Spinal Cord After Endovascular Stent Graft Repair of Thoracic Aneurysms". EJVES 2016 Dec 52 (6)
  78. Desai M, Choke E, Sayers RD, Nath M, Bown MJ. Sex-related trends in mortality after elective abdominal aortic aneurysm surgery between 2002 and 2013 at National Health Service hospitals in England: less benefit for women compared with men. Eur Heart J. 2016 Dec 7;37(46):3452-3460
  79. Koh K1, Koh YX, Choke ET, Wang JC, Kian CJ. Alternative Strategies for Central Venous Stenosis and Occlusion in Patients Requiring Haemodialysis Access. Ann Acad Med Singapore. 2017 Jan;46(1):39-41.
  80. Chia CS, Tay LHT, Wang JCC, Chong TT, Tay KH, Choke E. Treatment of an Aortic Arch Aneurysm with Scalloped and Fenestrated Thoracic Stent Graft and Left Carotid to Subclavian Artery Bypass. Ann Vasc Surg. 2017 Apr;40:300.e11-300.e15
  81. Dattani N, Ali M, Aber A, Kannan RY, Choke E, Bown MJ, Sayers RD, Davies RS. Cardiovascular Risk Reduction is Important for Improving Patient and Graft Survival After Ligation and Bypass Surgery for Popliteal Artery Aneurysm. Vasc Endovascular Surg. 2017 Jul;51(5):261-268.
  82. Choke E. Commentary to "Outcome After Turndown for Elective Abdominal Aortic Aneurysm Surgery" European Journal of Vascular & Endovascular Surgery. 2017 Nov:54(5): 587
  83. Attallah O, Karthikesalingam A, Holt PJ, Thompson MM, Sayers R, Bown MJ, Choke EC, Ma X. Using multiple classifiers for predicting the risk of endovascular aortic aneurysm repair re-intervention through hybrid feature selection. Proc Inst Mech Eng H. 2017 Nov;231(11):1048-1063
  84. Attallah O, Karthikesalingam A, Holt PJE, Thompson MM, Sayers R, Bown MJ, Choke EC, Ma X. Feature selection through validation and un-censoring of endovascular repair survival data for predicting the risk of re-intervention. BMC Med Inform Decis Mak. 2017 Aug 3;17(1):115. doi: 10.1186/s12911-017-0508-3.
  85. Choke E. Further Evidence for Regional Variation in Hospital Incidence of Abdominal Aortic Aneurysms: The German Data. Eur J Vasc Endovasc Surg. 2018 55, 860
  86. TY Tang, TT Chong, JCC Wang, EC Choke, KR Nair. NATROX® — Let the topical oxygen flow for healing complex wounds. Wounds Asia 2018;1(2).
  87. Tang TY, Walsh SR, Chong TT, Choke ETC, Tiwari A. Results of the EVRA trial will be a game-changer for the management of every venous ulcer. Phlebology. 2018 Dec;33(10):660-662.
  88. Choke E, de Borst GJ. Identification of Vulnerable Carotid Plaques: Contrasting Results from Contrast Enhanced Ultrasound Scan Studies. Eur J Vasc Endovasc Surg. 2018 Nov;56(5):643
  89. Yap HY, Chong TT, Tay HL, Lee QS, Chng JK, Wang CJ, Tay KH, Choke E. Fenestrated Endovascular Repair of Zones 1 and 2 Aortic Arch Pathologies. Ann Vasc Surg. 2019 Jan;54:145.e1-145.
  90. Choke E, Tang TY. Cystatins B and C - Same Family Different Associations. Eur J Vasc Endovasc Surg. 2018 Dec;56(6):833.
  91. Choke E. Timing is Right Only When You Choose What is Right. Eur J Vasc Endovasc Surg. 2018 Dec;56(6):783
  92. Choke E, Tan JSJ. Chewing the Rag: Masseters, Sarcopenia, and Late Survival After Carotid Surgery. Eur J Vasc Endovasc Surg. 2019 Mar;57(3):339.
  93. Tang TY, Rathnaweera HP, Kam JW, Chong TT, Choke EC, Tan YK. Endovenous cyanoacrylate glue to treat varicose veins and chronic venous insufficiency-Experience gained from our first 100+ truncal venous ablations in a multi-ethnic Asian population using the Medtronic VenaSeal™ Closure System. Phlebology. 2019 Sep;34(8):543-551.
  94. Foo J, Tang T, Damodharan K, Choke E. Type B Aortic Dissection post NELLIX endovascular aneurysm sealing (EVAS). Ann Vasc Surg. 2019 Feb 11. pii: S0890-5096(19)30114
  95. Tan CS, Tan SG, Wong CLJ, Wee B, Wong WK, Choke ETC, Tan RY, Liu P, Homer-Vanniasinkam S, Lau T, Choong LHL. Non-randomized safety and performance evaluation of the av-Guardian vascular access system. J Vasc Access. 2020 Jan 10
  96. Björck M, Earnshaw JJ, Acosta S, Bastos Gonçalves F, Cochennec F, Debus ES, Hinchliffe R, Jongkind V, Koelemay MJW, Menyhei G, Svetlikov AV, Tshomba Y, Van Den Berg JC, Esvs Guidelines Committee, de Borst GJ, Chakfé N, Kakkos SK, Koncar I, Lindholt JS, Tulamo R, Vega de Ceniga M, Vermassen F, Document Reviewers, Boyle JR, Mani K, Azuma N, Choke ETC, Cohnert TU, Fitridge RA, Forbes TL, Hamady MS, Munoz A, Müller-Hülsbeck S, Rai K. European Society for Vascular Surgery (ESVS) 2020 Clinical Practice Guidelines on the Management of Acute Limb Ischaemia. Eur J Vasc Endovasc Surg. 2020 Feb;59(2):173-218
  97. Choke E, Tang TY, Cheng SC, Tay JS. Treatment of lower limb ischaemia in patients with diabetes. Diabetes Metab Res Rev. 2019 Dec 12
  98. Tang TY, Rathnaweera HP, Choke E, Tiwari A, Chong TT. Institution of a Double-Dosing Protocol Using Cyanoacrylate Glue for Larger Diameter Refluxing Superficial Truncal Veins. Dermatol Surg. 2019 Nov;45(11):1426-1429.
  99. Tang TY, Choke EC, Walsh SR, Tiwari A, Chong TT. What Now for the Endovascular Community After the Paclitaxel Mortality Meta-Analysis: Can Sirolimus Replace Paclitaxel in the Peripheral Vasculature? J Endovasc Ther. 2020 Feb;27(1):153-156.
  100. 100.  Choke ETC, Tay JS. Achieving Thinned Blood: One Size Fits All? Eur J Vasc Endovasc Surg. 2020 Jan;59(1):148.
  101. Chan SS, Tang TY, Chong TT, Choke EC, Tay HT. Retrograde technique for great saphenous vein ablation using the VenaSeal™ closure system - Ideal approach for deep seated or small below the knee refluxing truncal veins. Phlebology. 2020 Mar;35(2):102-109.
  102. Kabir T, Choke ETC, Kam JH. Unusual discovery in the liver: intrahepatic portal vein aneurysm. ANZ J Surg. 2019 Apr 11.
  103. Tang TY, Tan CS, Yap C, Tan RY, Tay HH, Choke E, Chong TT. Helical stent (SUPERA™) and drug-coated balloon (Passeo-18 Lux™) for recurrent cephalic arch stenosis: Rationale and design of arch V SUPERA-LUX Study. J Vasc Access. 2019 Oct 17:1129729819881589
  104. Tang TY, Goh R, Damodharan K, Choke EC, Chong TT, Tan YK. RE: "Long-term follow-up of stenting across the ilio-caval confluence in patients with iliac venous lesions": the value of using IVUS and a dedicated oblique venous stent for deep vein work involving the ilio-caval bifurcation. J Thromb Thrombolysis. 2019 Feb;47(2):328-330
  105. Chan SSJ, Yap CJQ, Tan SG, Choke ETC, Chong TT, Tang TY. The utility of endovenous cyanoacrylate glue ablation for incompetent saphenous veins in the setting of venous leg ulcers. J Vasc Surg Venous Lymphat Disord. 2020 Mar 20.
  106. Choke E, Verhoeven E. Uncomplicated Type B Aortic Dissection: Complicated Choices. Eur J Vasc Endovasc Surg. 2020 Aug;60(2):201-202
  107. Choke E, Tay JS. SISMAD: Leave Alone or Stent? Eur J Vasc Endovasc Surg. 2020 ;DOI:https://doi.org/10.1016/j.ejvs.2020.08.041

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