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General Modes of Treatment

Pathologic Diagnosis Of Cancer

The diagnosis of cancer requires the taking of a tissue sample from you, so that it can be processed for examination under the microscope by a pathologist for confi rmation of cancer. The type and grade of the cancer can also be determined on microscope examination. The tissue sample can be obtained through a biopsy or fine needle aspiration procedure, which involves either the removal of a small amount of tissue, or aspirating cells from the lump, for histologic evaluation.

Surgery is the most effective treatment for a solid tumour when it is operable. However, every person is diff erent and needs an individual treatment plan. The treatment plan depends on the type, location, size, stage and grade of cancer. During surgery, the surgeon removes the section of the tissue that is affected. Nearby lymph glands will also be removed because if the cancer has spread, it usually spreads first to the lymph glands.

Chemotherapy is the use of anticancer drugs to kill cancer cells. They stop cancer cells from growing and reproducing themselves. These drugs can be given orally or by injections. The drugs enter the bloodstream and travel throughout the body. Drugs may be used alone, before or after surgery, or together with radiation therapy to increase the effectiveness of treatment.

Chemotherapy is given in cycles. Each cycle consists of a treatment period followed by a resting (recovery) period. As cancer drugs also affect normal cells, the resting period is to allow the body to recover before the next treatment cycle starts. There are side effects associated with chemotherapy such as hair loss, nausea and vomiting, loss of appetite, mouth ulcers and risks of infection. However, these are temporary and steps can be taken to prevent or reduce them.

Radiation Therapy uses radiation to kill cancer cells or stop them from growing further. Although radiation therapy can aff ect both cancer cells as well as normal cells, the aim of radiation is to destroy more cancer cells and spare as many normal cells as possible.

The two ways of delivering radiation are using external beam and brachytherapy. In external beam radiotherapy, machines called linear accelerators (linacs) produce high energy x-rays that is used for treatment. In contrast, radioactive sources are applied in close contact to the tumour for treatment in brachytherapy.

Radiation therapy can cause side effects, which varies between individuals and diff erent treatment sites. For example, treatment of the head and neck region may cause dryness of mouth or painful swallowing, whereas patients receiving treatment to the abdominal area may experience diarrhoea. Most of these side eff ects are temporary and are manageable. Newer radiotherapy techniques can minimise these side effects.

Hormone Therapy or Endocrine Manipulation is a therapy that aims to control a cancer by changing the hormonal environment in which it is growing. Hormone is a substance which has specifi c eff ect on the way the body works. Made in very small amounts by glands, various hormones help to regulate and coordinate growth, metabolism and reproduction. They are distributed in the bloodstream. Cancer of the breast or prostate, for example, can respond well to hormone treatment.