Colchicine is used for the treatment and prevention of gout flares, which is a condition that can cause pain, redness, and swelling in the joints (big toe, ankle, or knee). Gout is caused by too much uric acid when the body breaks down chemicals called purines. Hence, excess uric acid can build up in the joints and cause gout pain. In addition, gout can be affected by conditions, such as diabetes, poor kidney function, obesity, cancer, medications, or eating purine-rich food (alcohol, seafood, and other foods).
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