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Dr Wee Tian Seng Joseph from National Cancer Centre Singapore

Adj Assoc Prof Wee Tien Seng Joseph

​MBBS, FRCR (Clinical Oncology)(UK)

Senior Consultant

Specialty: Radiation Oncology, Radiation Oncology

Sub-specialties: Head & Neck, Nasopharynx

Conditions Treated by this Doctor:
Head and Neck Cancer.

Clinical Appointments

  • Senior Consultant Division of Radiation Oncology National Cancer Centre SingaporeNational Cancer Centre Singapore


​Dr Wee is a Senior Consultant at the Division of Radiation Oncology

He subspecialises in Head and Neck Oncology with special interests in Nasopharyngeal Carcinoma (NPC).

He was awarded the National Medical Research Council Clinician Scientist Award (Senior Investigator), from 2009-2013. He started the Intensity Modulated Radiation Therapy (IMRT) program for NPC in Singapore in 2002. He was also the Principal Investigator for 2 Randomised Phase 3 trials for NPC. He sits on the Editorial Board of several Oncology journals.


​MBBS, FRCR (Clinical Oncology)(UK)

Professional Appointments and Committee Memberships


  • Member, International Advisory Board, Editorial Board
    International Journal of Radiation Oncology, Biology & Physics 2012 - current
  • Associate Editor
    Chinese Journal of Cancer 2012- current
  • Guest Editor
    Chinese Clinical Oncology (issue on Nasopharyngeal Carcinoma) 2015- 2016
  • Editorial Board member
    Chinese Clinical Oncology 2016 - current
  • Editorial Board member
    Annals of Nasopharyngeal Cancer 2017 - current
  • Editorial Board member
    Journal of XiangYa Medicine 2017 - current
  • International Editorial Board Member
    Radiation Oncology Journal (South Korea) 2015 - current
  • Member, Editorial Board
    Journal of Radiation Oncology 2011- current
  • Member, Editorial Board
    Oral Oncology 2009 - current
  • Honorary Advisor,
    Journal of Hong Kong College of Radiologists 2005 – current
  • ​President, Singapore Society of Oncology 2000 - 2002
  • Member, 36th Council, Singapore Cancer Society 2000 - 2001
  • Hon Auditor, Singapore Society of Oncology 2002
  • Hon Secretary, Chapter of Radiologists Academy of Medicine, Singapore 1996 - 1998
  • Hon Auditor, Singapore Radiological Society 1997
  • Hon Treasurer, Singapore Radiological Society 1996
  • Hon Treasurer, Singapore Society of Oncology 1994 - 1995
  • Member, Medical Advisory Sub-committee Breast Cancer Foundation, Singapore 1998 – Present
  • Hon Treasurer, Medical Society / Medical Club ational University of Singapore  1979 - 1980
    Secretary, Organising Committee, 6th Advanced Course in Head & Neck Cancer Surgery
  • S’pore Assoc of Head & Neck Surgeons / Academy of Medicine 1997 - 1998
  • Member, Organising Committee, 7th Annual Scientific Meeting, S’pore Radiological Society / Academy of Medicine 1998
  • Member, Facilities Subcommittee, 9th Annual Scientific Meeting, Singapore General Hospital 1998
  • Chairman, Organising Committee, 5th Annual Scientific Meeting, S’pore Radiological Society / Academy of Medicine  1996
    National Cancer Centre Singapore
  • Member, Executive Committee 2001
  • Member, Medical Board 2007
  • Member, Research Comittee 2001
  • Co-Chairman, Disease Outbreak Response System Task Force 2006 - 2009
  • Chairman, JCI Steering Committee 2008 - 2010
  • Member, Quality Assurance Committee 2007
  • Member, Singhealth Research Committee 2001 - 2002
  • Infection Control Officer, SARS Task Force 2003
  • Programme Leader, Nasopharyngeal Cancer
  • Cancer Service Line Development Programme 2004 - 2006
  • Chairman, NPC Tumour Specific Workgroup 2002
  • Member, Clinical Trials Steering Committee 2000 - 2005
  • Leader, National Medical Research Council / National Cancer Centre Delegation to Hong Kong to discuss
  • Nasopharyngeal Cancer Trails in Asia-Pacific Hong Kong, SAR  2000
  • Member, National Medical Research Council Delegation to Trans-Tasman  Radiation Oncology Group Newcastle, Australia  1999
  • Member, Singapore General Hospital Delegation to 6th UCSF-Stanford – SGH Joint Update, San Francisco  1999
  • Member, National Medical Research Council Delegation to University of Udayana, Bali, Indonesia Site inspection for NMRC Trials  1998
  • Member, Advisory Panel Cancer Helpline  
  • Member, Media Committee  
  • Vice Chairman and Secretary Nasopharyngeal Cancer Workgroup  1997 - present


  • Head & Neck Cancer Subcommittee
  • Lung Cancer Subcommittee 
  • Upper Gastrointestinal Cancer Subcommittee, 1997 - present
  • Member, Electronic Medical Records Workgroup, Singapore General Hospital  1997 - 1998
  • Departmental Representative,  DRG Committee, Singapore General Hospital  1998 - 2000


  • Singapore National Day Awards, Public Administration Medal (Silver) 2018
  • Singapore National Day Awards, The Long Service Medal 2015
  • Chinese Journal of Cancer, Chinese Journal of Cancer Award for paper which was highly cited 2015
  • Singapore Health Services, SingHealth GCEO Excellence Award - Outstanding Clinician Award 2012
  • Dr. K. C. Borooah Foundation Day Oration Committee, Dr. K. C. Borooah Foundation Day Oration 2010
  • National Medical Research Council, Clinician Scientist Award (Senior Investigator) 2009    
  • Singapore Radiological Society and College of Radiologists, 4th FY Khoo Lecturer 2008
  • Singapore Armed Forces National Service Medal 2000 
  • Singapore General Hospital Service with a Heart Award Oct 1997 
  • Singapore Armed Forces Good Service Medal 1997 
  • Public Services Commission - Health Manpower Development Plan Scholarship for a fellowship in Clinical Oncology at The Middlesex Hospital, London 1989 - 1991 
  • Local Merit Bursary (Public Services Commission) to study Medicine at the National University of Singapore 1978 - 1983

Publications and Research Trials

  • Chua Melvin L K; Wee Joseph T S; Hui Edwin P; Chan Anthony T C. Nasopharyngeal carcinoma. Lancet (London, England) 2016; 387(10022):1012-124
  • Wee Joseph Tien Seng; Soong Yoke Lim; Chua Melvin Lee Kiang. Nasopharyngeal carcinoma-past lessons and a glimpse into the future. Chinese clinical oncology 2016; 5(2):
  • Sim CP, Wee J, Xu Y et al. Anti-caries effect of CPP-ACP in irradiated nasopharyngeal carcinoma patients. Clin Oral Investig. 2014 Sep 27. [Epub ahead of print].
  • Quoted in: EBV in Asia: Nasopharyngeal carcinoma – pg 99. In: Crawford DH, Rickinson A (Eds). Cancer Virus – The Story of Epstein-Barr Virus. Oxford, Oxford University Press, 2014
  • Sun Y, Yu XL, Luo W, Lee AW, Wee JT, Lee N et al. Recommendation for a contouring method and atlas of organs at risk in nasopharyngeal carcinoma patients receiving intensity-modulated radiotherapy. Radiother Oncol. 2014 Mar;110(3):390-7. (JIF 4.857)
  • Wee J, Tan EH, Tai BC et al. Randomized trial of radiotherapy versus concurrent chemo-radiotherapy followed by adjuvant chemotherapy in patients with AJCC Stage III and IV nasopharyngeal cancer of the endemic variety. In: Shah JP ed. A Century of Progress in Head and Neck Cancer. Philadelphia, Jaypee Brothers Medical Publishers, 2014
  • Tham I, Cheah SL, Soong YL, Wee J. Commentary: Retrospective Analysis of 5037 patients with nasopharyngeal carcinoma treated during 1976-1985: overall survival and patterns of failure. In: Shah JP ed. A Century of Progress in Head and Neck Cancer. Philadelphia, Jaypee Brothers Medical Publishers, 2014
  • Yom S and Wee J. 14.ASK THE EXPERTS: Maximizing the therapeutic ratio in the treatment of nasopharyngeal carcinoma. In: Yom S and Wee J ed. Clinical Insights: Nasopharyngeal Carcinoma – Management Strategies. (eBook) London, Future Medicine, 2014.
  • Yom S and Wee J ed. Clinical Insights: Nasopharyngeal Carcinoma – Management Strategies. (eBook) London, Future Medicine, 2014
  • Toh HC, Ha TC, Wee J. Invited Commentary: Personalized Medicine in Nasopharyngeal Cancer. Lancet Oncol 2012 May 2. [Epub ahead of print] (JIF 22.59)
  • J Wee. Invited Commentary: Nasopharyngeal Carcinoma – a promising future. Lancet Oncol 2012 Feb;13(2):116-8. Epub 2011 Dec 15 (JIF 22.59)
  • Hai-Yun Wang, Bing-Yu Sun, Zhi-Hua Zhu…. Wee J.. et al. An Eight-signature Classifier for Prediction of Nasopharnyngeal Carcinoma Survival. J Clin Oncol. 2011 Dec 1;29(34):4516-25. Epub 2011 Oct 24. (JIF 18.97)
  • Tham IW, Lin S, Pan J,.. Wee J. Intensity-Modulated Radiation Therapy Without Concurrent Chemotherapy for Stage IIB Nasopharyngeal Cancer. Am J Clin Oncol. 2010 Jun;33(3):294-9 (JIF 1.768)
  • Lee Anne W; Ng Wai Tong; Pan Jian Ji; Poh Sharon S; Ahn Yong Chan; AlHussain Hussain; Corry June; Grau Cai; Grégoire Vincent; Harrington Kevin J; Hu Chao Su; Kwong Dora L; Langendijk Johannes A; Le Quynh Thu; Lee Nancy Y; Lin Jin Ching; Lu Tai Xiang; Mendenhall William M; O'Sullivan Brian; Ozyar Enis; Peters Lester J; Rosenthal David I; Soong Yoke Lim; Tao Yungan; Yom Sue S; Wee Joseph T. International guideline for the delineation of the clinical target volumes (CTV) for nasopharyngeal carcinoma. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2018; 126(1):25-36
  • Tan Terence; Lim Wan-Teck; Fong Kam-Weng; Cheah Shie-Lee; Soong Yoke-Lim; Ang Mei-Kim; Ng Quan-Sing; Tan Daniel; Ong Whee-Sze; Tan Sze-Huey; Yip Connie; Quah Daniel; Soo Khee-Chee; Wee Joseph. Concurrent chemo-radiation with or without induction gemcitabine, Carboplatin, and Paclitaxel: a randomized, phase 2/3 trial in locally advanced nasopharyngeal carcinoma. International journal of radiation oncology, biology, physics 2015; 91(5):952-96
  • Sun Ying; Yu Xiao-Li; Luo Wei; Lee Anne W M; Wee Joseph Tien Seng; Lee Nancy; Zhou Guan-Qun; Tang Ling-Long; Tao Chang-Juan; Guo Rui; Mao Yan-Ping; Zhang Rong; Guo Ying; Ma Jun. Recommendation for a contouring method and atlas of organs at risk in nasopharyngeal carcinoma patients receiving intensity-modulated radiotherapy. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2014; 110(3):390-377
  • Grégoire Vincent; Evans Mererid; Le Quynh-Thu; Bourhis Jean; Budach Volker; Chen Amy; Eisbruch Abraham; Feng Mei; Giralt Jordi; Gupta Tejpal; Hamoir Marc; Helito Juliana K; Hu Chaosu; Hunter Keith; Johansen Jorgen; Kaanders Johannes; Laskar Sarbani Ghosh; Lee Anne; Maingon Philippe; Mäkitie Antti; Micciche' Francesco; Nicolai Piero; O'Sullivan Brian; Poitevin Adela; Porceddu Sandro; Składowski Krzysztof; Tribius Silke; Waldron John; Wee Joseph; Yao Min; Yom Sue S; Zimmermann Frank; Grau Cai. Delineation of the primary tumour Clinical Target Volumes (CTV-P) in laryngeal, hypopharyngeal, oropharyngeal and oral cavity squamous cell carcinoma: AIRO, CACA, DAHANCA, EORTC, GEORCC, GORTEC, HKNPCSG, HNCIG, IAG-KHT, LPRHHT, NCIC CTG, NCRI, NRG Oncology, PHNS, SBRT, SOMERA, SRO, SSHNO, TROG consensus guidelines. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2018; 126(1):3-24
  • Li You Quan; Tian Yun Ming; Tan Sze Huey; Liu Ming Zhu; Kusumawidjaja Grace; Ong Enya H W; Zhao Chong; Tan Terence W K; Fong Kam Weng; Sommat Kiattisa; Soong Yoke Lim; Wee Joseph T S; Han Fei; Chua Melvin L K. Prognostic Model for Stratification of Radioresistant Nasopharynx Carcinoma to Curative Salvage Radiotherapy. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2018; 36(9):891-899

Research Trials