grown from “induced pluripotent stem cells” derived from the lining of a human umbilical cord, by a team of local scientists who think that such regeneration of neurons could be used to reverse the
effects of Parkinson’s.
Scientists here have succeeded in using stem cells
derived from the umbilical cord lining to generate
new dopamine-producing nerve cells in mice.
People with Parkinson’s disease progressively
lose control of their movements due to a disruption
in the brain’s production of dopamine neurons,
which send signals to other nerve cells.
There is currently no effective treatment.
The team from the National University of Singapore
and the National Neuroscience Institute
thinks that regenerating these neurons could possibly
reverse the effects of Parkinson’s.
Associate Professor Lim Kah Leong, one of the
lead researchers of the study, said that if the technique
is successful in humans, it could be the first
treatment to target the root cause of the disease,
which afflicts three out of every 1,000 people aged
over 50 here – costing each patient an estimated
$11,000 in medical bills per year.
The team made use of a technique developed by
Nobel laureate Shinya Yamanaka to turn mature
cells into “induced pluripotent stem cells” capable
of turning into any cell the body needs.
It is also looking at using the same technique to
combat other neurological conditions, such as
strokes.
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