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Teo Ching Ching Melissa
Adj Assoc Prof Teo Ching Ching Melissa
National Cancer Centre Singapore
Division of Surgical Oncology
Senior Consultant/Head
MBBS, MMed (Surg), FRCSEd, FAMS, MPH

Adj A/Prof Teo is the Head of the Division of Surgical Oncology at the National Cancer Centre Singapore.  She is one of few accredited surgical oncologists in Singapore.  She completed her surgical residency in Singapore (2007) and was awarded the Singhealth HMDP Award to pursue sub-specialty training in complex intra-abdominal and pelvic surgery in the University of Toronto/ Princess Margaret Hospital, Toronto, Canada. Upon completion of an SSO-accredited Surgical Oncology Fellowship, she pursued and completed a second Fellowship in Colorectal Surgery. Interested in policy development, she received an NMRC Award, enrolled in the John Hopkins Bloomberg School of Public Health, and graduated in December 2009 with a Master of Public Health and an additional Diploma in Health Policy and Financial Management.

She returned to work at the National Cancer Centre Singapore (NCCS), as a Senior Consultant and was appointed the Director of the NCCS Centre for Peritoneal and Pelvic Disease.  The centre now has the largest experience with the surgical management of peritoneal-based malignancies in Asia.  She has been a strong advocate for improving cancer care in Singapore, and is a member of the Singapore Society of Oncology, sits on the Singapore Cancer Network Sarcoma Guideline Committee and is a member of the Ministry of Health Technology Advisory Committee. At NCCS, she co-chairs the Paediatrics/Sarcoma/ Melanoma workgroup and is a member of the Gastrointestinal Tract workgroup for NCCS Cancer Service Line.  She is also the chairperson for the new NCCS Building Committee and Director of Strategic Initiatives of ACP Oncology.

Adj A/Prof Teo has held many research leadership positions and is the PI of more than 38 IRBs, authored more than 78 peer-reviewed publications, and 5 book chapters.

Her mission as a surgical oncologist is to improve cancer care in Singapore and the region, through increased patient awareness of the disease, and its management, contributing to the setting of guidelines and pushing the frontiers for cancer management in her areas of expertise and education of the next generation of surgical residents, clinical fellows and medical students.

Education

MBBS (S’pore), FRCS (Edin), MPH (Johns Hopkins)


FELLOWSHIPS

Surgical Oncology (University of Toronto), Colorectal Surgery (University of Toronto)

Professional Appointments and Committee Memberships

     - Member, Singapore Medical Association
- Member, General Medical Council (UK)
- Member, Singapore Society of Oncology
- Fellow of Academy of Medicine, Singapore
- Fellow of Royal College of Surgeons, Edinburgh
- Member, The College of Physicians and Surgeons of Ontario
- Member, Canadian Society of Surgical Oncology
- Member, The Society of Surgical Oncology, Inc
- Clinical Senior Lecturer, Yong Loo Lin School of Medicine (Aug 2012 to Jul 2015)
- Adjunct Associate Professor, Duke-NUS GMS (Jan 2011 to Present)

Awards

- DukeNUS Medical School  - Outstanding Faculty for Surgery, 2016
- SingHealth Excellence Award 2015 – Distinguished Young Leader Award
- DukeNUS Medical School - Outstanding Faculty for Surgery, 2015
- Certificate of Commendation for being a Role Model to the Class of 2014 – Yong Loo Lin School of Medicine
-  Yong Loo Lin School of Medicine Awards and Appreciation Nite 2013: Outstanding Tutor Award
-  NMRC Clinician Scientist: Individual Research Grant (CS-IRG), 2013
-  Outstanding Faculty Award – voted by your residents at the RISE award 2013
-  Terry Fox Research Grant – Molecular Signature of Peritoneal Metastasis, 2012
-  Yong Loo Lin School of Medicine: Best Tutor Awards, 2012
-  Service With A Heart Award, Singapore General Hospital, 2012
-  Surgical Star – Inspiring Teacher Award (Division of Surgery, SGH), 2011
- NMRC Research Training Fellowship – MPH (John Hopkins Bloomberg School of Public Health), 2008


Publications and Research Trials

Publications and Research Trials:
1 Healthcare Worker Seroconversion in SARS outbreak
P Chow, Eng EO, HK Tan, Kw Ong, BK Sil, M Teo, T Ng, KC Soo
      Emerging Infectious Diseases Journal Feb 2004; 10:2

2   Bevacizumab and rapamycin inhibit tumor growth in peritoneal model of human ovarian cancer
     Huynh H, M Teo, Soo KC 
     Mol Cancer Ther. 2007 Nov; 6(11):2959-66

3 Preoperative radiation with concurrent chemotherapy for resectable rectal cancer: long-term follow-up results of a dose escalation study 
M Teo, Ridgway PF, Wiltshire KL, Ward IG, Swallow CJ, Oza AM, Cummings B, Pond GR, Catton P, Kim J, Ringash J, Wong R, Siu L, Moore M, Brierley J
 Canadian Journal of Surgery (suppl) 2008: 51: pp 38 

4 First Somatic Mutation of E2F1 in a Critical Binding Residue Discovered in Well-differentiated Papillary Mesothelioma of the Peritoneum 
W Yu, W Chan-On, M Teo, Ong CK, I Cutcutache, GE Allen, B Wong, M Swe Swe, Lim KH, PM Voorhoeve, S Rozen, Soo KC, P Tan, Teh BT.
Genome Biology Sept 2011; 12(9)

5 Cancer Trends and Incidences in Singapore 
M Teo, KC Soo 
Japanese Journal of Oncology (JJCO  Manuscript JJCO-12-0178.RI)DOI: 10.1093/jjco/hys230

6 Cutaneous vs Non-Cutaneous Angiosarcoma: Clinicopathologic Features and Treatment Outcomes in 60 Patients At a Single Asian Cancer Centre.
F Mohamad, WS Ong, M Lee, R Jeevan, ZC Ho, A N H Sairi, LT Soh, D Poon, YH Teh, F Chin, M Teo, R Quek.
Oncology 2013 85 (3): 182-90

7   Quality of Life After Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy: An Asian Perspective
     Tan WJ, Wong JF, Chia CS, Tan GH, Soo KC, M Teo 
Ann Surg Oncol 2013, 4219-23 20(13)

8  The influence of Primary Site on outcomes in leiomyosarcoma: a review of clinicopathologic differences between uterine and extrauterine disease 
Farid M, Ong WS, Tan MH, Foo LS, Lim YK, Chia WK, Soh LT, Poon D, Lee MJ, Ho ZC, Jeevan R, Chin F, M Teo, Quek R
American Journal of Clinical Oncology, 2013 Aug;36(4):368-74. Doi: 10.1097/COC.0b013e318248dbf4 PMID: 22772425

9   Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Asian Patients: 100 Consecutive Patients in a Single Institution
M Teo, G Tan, CK Tham, C, KC Soo 
Annals of Surgical Oncology 2013 Sep;20(9):2968-74. doi: 10.1245/s10434-013-2947-0 Epub 2013 Mar 17

10  Peri-operative morbidity and Quality of Life Outcomes following Cytoreductive Surgery (CRS) and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Asian Patients
W Tan, C Chia, G Tan, J Wong, M Teo 
Annals of Surgical Oncology. Sept 2013

11  The influence of primary site on outcomes in leiomyosarcoma: a review of clinicopathologic differences between uterine and extrauterine disease.
Farid M, Ong WS, Tan MH, Foo LS, Lim YK, Chia WK, Soh LT, Poon D, Lee MJ, Ho ZC, Jeevan R, Chin F, M Teo, Quek R. 
Am J Clin Oncol. 2013 Aug;36(4):368-74.

12  Validation of the MSKCC Gastrointestinal Stromal Tumor Nomogram and comparison with current prognostication systems: single institution experience with 289 Asian patients
Chok AY, B Goh, Koh YX, Lye WK, John C. A, R Quek, M Teo, P Chow, Ong HS, A Chung, Wong WK
Ann Surg Oncol. 2015 Oct; 22(11): 3597-605. doi: 10.1245/s10434-015-4400-z. Epub 2015 Feb 5.

13  Whole exome sequencing of breast cancer, malignant peripheral nerve sheath tumour (MPNST) and neurofibroma from a patient with neurofibromatosis type 1 (NF1) 
J R McPherson, CK Ong, C CY Ng, V Rajasegaran, HL Heng, W SS Yu, B KT Tan, P Madhukumar, M Teo, J YY Ngeow, AA Thike, S Rozen, PH Tan, A SG Lee, BT Teh, YS Yap
Cancer Med. 2015 Oct 3. doi: 10.1002/cam4.551. [Epub ahead of print]

14  National Cancer Center Singapore: the way forward
M Teo, Soo KC 
2016 Future Medicine 10.2217/fon.15.331

15  Blood neutrophil-to-lymphocyte and platelet-to-lymphocyte ratio are independent prognostic factors for surgically-resected gastrointestinal stromal tumors
B Goh, AY Chok, J. C. Allen, R Quek, M Teo, P Chow, A Chung, HS Ong, WK Wong
Surgery. 2015 Dec 10. pii: S0039-6060(15)00892-2. [Epub ahead of print]

16  Two rare cases of appendiceal collision tumours involving an appendiceal mucinous neoplasm and carcinoid
Tan HL, G Tan, M Teo 
BMJ Case Reports 2016;Doi: 10.1136/bcr-2015-213938

17 Does Early Postoperative Intraperitoneal Chemotherapy (EPIC) for Patients treated with Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) make a different?
G Tan, Ong WS, C Chia, Tham CK, Soo KC, M Teo
Int J Hyperthermia. 2016 Feb 10:1-8. 

18 Prospective quality of life study for colorectal cancer patients with peritoneal carcinomatosis undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy
C Chia, G Tan, C Lim, Soo KC, M Teo 
Annals of Surgical Oncology 2016 Mar 25 (Epub ahead of print) Pp 1-9

19 Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in the management of uterine leiomyosarcoma with peritoneal sarcomatosis: a case report and review of the literature
L. Chen, M Teo  
Journal of cases in Obstetrics & Gynaecology (Accepted)

20 Acute Kidney Injury In Ovarian Cancer Patients Undergoing Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy
E Sin, C Chia, C Lim, G Tan, Soo KC, M Teo
Int Journal of Hyperthermia (Accepted)

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