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Tan Ee Shien
Dr Tan Ee Shien
KK Women's and Children's Hospital
Medicine: Dept of Paediatrics, Genetics Service
Head & Senior Consultant

Dr Tan started practice as a general paediatrician in 2002 and subsequently trained in the area of clinical genetics and genetic metabolic disease. She is involved in medical education, in both the Yong Loo Lin School of Medicine, NUS and Duke graduate medical school. She is also heavily involved in research, obtaining the Singhealth Clinician Scientist Award in 2008.

Her current interests include the clinical management of inborn errors of metabolism and expanded newborn screening.

  • MBBS, University of Singapore 
    • 1998
  • MRCPCH, Royal College of Paediatrics and Child Health, United Kingdom 
    • 2002
Professional Appointments and Committee Memberships
  • Consultant, Department of Paediatric Medicine
  • Clinical Lecturer, National University of Singapore 
    • 2009-present
  • Clinician Scientist, Singhealth 
    • 2008–2011
  • Asst Professor, Duke GMS 
    • 2008-present
  • Visiting Consultant, National University Hospital 
    • 2010-present
  • Asst Director, Expanded newborn screening program  
    • 2010-present
  • Health Manpower Development Plan Award 
    • 2005
  • Singhealth Clinician Scientist Award 
    • 2008-2011
  • KKH Service From the Heart Award 
    • 2008
  • EXSA Gold Award 
    • 2008
  • EXSA Star Award 
    • 2009
  • Singhealth Quality Service Gold Award 
    • 2010
Publications and Research Trials
  1. SMN1 deletions among Singaporean patients with spinal muscular atrophy, 2005
  2. D2 Hydroxyglutaric Aciduria – A rare cause of developmental delay, 2006
  3. The clinical spectrum of 22q11 deletion syndrome in Singapore, 2003
    Non-Ketotic Hyperglycinemia is usually not detectable by tandem mass spectrometry newborn screening, 2007
  4. Inborn errors of metabolism presenting as neonatal encephalopathy : Practical tips for clinicians, 2008
  5. Amelioration of oxidative stress in red blood cells from patients with ß-thalassemia major and intermedia and E-ß-thalassemia following administration of fermented papaya preparation, 2010
  6. Recognition and management of the newborn with inborn errors of metabolism, 2010
  7. Clinical and laboratory barriers to the timely diagnosis of sulphite oxidase deficiency, 2010
  8. The clinical effects of fermented papaya preparation on oxidative stress in patients with HbE Beta Thalassaemia, 2010
  9. Neonatal Seizures : When to consider and how to investigate for an inborn error of metabolism, 2010
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