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National Neuroscience Institute
Assoc Prof Deidre Ann De Silva
National Neuroscience Institute
Neurology (SGH Campus)
Senior Consultant
MBBS, MRCP(UK), FAMS (Neurology)

Dr Deidre DeSilva  graduated from the National University of Singapore. After internal medicine training and attaining Membership to the Royal College of Physician, she underwent advanced specialist neurology training. Following this, she undertook a one-year clinical stroke fellowship at the Royal Melbourne Hospital under the mentorship of Professor Stephen Davis. Subsequently, she completed a one-year stroke research fellowship, working with various stroke groups including those at Georgetown University, Stanford University and the Royal Melbourne Hospital.

Dr Deidre DeSilva sub-speciality is stroke neurology and she has interests in the profile of Asian stroke patients, novel stroke risk factors, acute reperfusion strategies and advanced imaging techniques.


Professional Appointments and Committee Memberships

  • Director (Clinical Research/SGH), Neuroscience Academic Clinical Programme

  • Associate Professor, Duke-NUS Graduate Medical School

  • Clinical Tutor, National University of Singapore

  • Executive Committee Member, Chapter of Neurology, Academy of Medicine

  • Secretary, Clinical Neuroscience Society


  • National Medical Research Council Medical Research Fellowship

  • Royal Melbourne Hospital Stroke Fellowship

  • Singhealth Publish Award (Outstanding) 2011

  • Singhealth Medical Research Publication Award 2010

  • First prize, oral paper, Singapore General Hospital annual scientific meeting 2009

  • First Prize, Young Investigator Award (Clinical), Singapore General Hospital annual scientific meeting 2006

Publications and Research Trials

1) De Silva DA, Manzano JJ, Toh A, Woon FP, Liu EY, Omar E, Wong WX, Wong TY, Chen CP, Chang HM, Wong MC. Lower incidence of vascular events following small artery ischemic stroke. Int J Stroke 2012; 7: 361-362. (Impact factor 2.382)

2) De Silva DA, Churilov L, Olivot JM, Christensen S, Lansberg MG, Mlynash M, Campbell BC, Desmond P, Straka M, Bammer R, Albers GW, Davis SM, Donnan GA. Greater effect of stroke thrombolysis in the presence of arterial obstruction. Ann Neurol 2011; 70: 601-605. (Impact factor 10.746)

3) De Silva DA, Woon FP, Manzano JJ, Liu EY, Chang HM, Chen C, Wang JJ, Mitchell P, Kingwell BA, Cameron J, Lindley RI, Wong TY, Wong MC. The relationship between aortic stiffness and changes in retinal microvessels among Asian ischemic stroke patients. J Hum Hypertens 2011; [Epub]. (Impact factor 2.802)

4) De Silva DA, Manzano JJ, Chang HM, Wong MC. Reconsidering recent myocardial infarction as a contraindication for IV stroke thrombolysis. Neurology 2011; 76: 1838-1840. (Impact factor 8.172)

5) De Silva DA, Manzano JJ, Liu EY, Woon FP, Wong WX, Chang HM, Chen C, Lindley RI, Wang JJ, Mitchell P, Wong TY, Wong MC. Retinal microvascular changes and subsequent vascular events after ischemic stroke. Neurology 2011; 77: 896-903. (Impact factor 8.172)

6) De Silva DA, Manzano JJ, Woon FP, Liu EY, Lee MP, Gan HY, Chen CP, Chang HM, Mitchell P, Wang JJ, Lindley RI, Wong TY, Wong MC. Associations of retinal microvascular signs and intracranial large artery disease. Stroke 2011; 42: 812-814. (Impact factor 5.729)

7) De Silva DA, Ebinger M, Christensen S, Parsons MW, Levi C, Butcher K, Barber PA, Bladin C, Donnan GA, Davis SM. Baseline diabetic status and admission blood glucose were poor prognostic factors in the EPITHET trial. Cerebrovasc Dis 2010; 29: 14-21. (Impact factor 3.535)

8) De Silva DA, Brekenfeld C, Ebinger M, Christensen S, Barber PA, Butcher KS, Levi CR, Parsons MW, Bladin CF, Donnan GA, Davis SM. The benefits of intravenous thrombolysis relate to the site of baseline arterial occlusion in the Echoplanar Imaging Thrombolytic Evaluation Trial (EPITHET). Stroke 2010; 41: 295-299. (Impact factor 5.729)

9) De Silva DA, Ancalan M, Doshi K, Chang HM, Wong MC, Chen C. Intracranial large artery disease in Alzheimer's disease and vascular dementia among ethnic Asians. Eur J Neurol 2009; 16: 643-645. (Impact factor 2.437)

10) De Silva DA, Woon FP, Gan HY, Chen CP, Chang HM, Koh TH, Kingwell BA, Cameron J, Wong MC. Arterial stiffness is associated with intracranial large artery disease among ethnic Chinese and South Asian ischemic stroke patients. J Hypertens 2009; 27: 1453-1458. (Impact factor 4.021)

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