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Age-Related Macular Degeneration (AMD)

Overview
Causes
Symptoms
Risk Factors
Prevention
Treatment Options
Where to Seek Treatment
Singapore National Eye Centre
Contributed by Vitreo-Retina Service

AGE-RELATED MACULAR DEGENERATION

If haziness or blank spots appear in your central vision, or if you find that straight lines look a little wavy to you, see your eye doctor─it could be a sign of age-related macular degeneration, an eye condition that could lead to severe vision loss.

What is Age-Related Macular Degeneration?

It is a chronic irreversible medical condition that results in loss of vision central because of damage to the macula, or central part of the retina. Age-related macular degeneration (AMD) is a major cause of blindness in those over 50 years old. The condition can make it difficult to read or recognise faces, although enough peripheral vision (vision outside the central area of your gaze) remains to allow you to continue with other daily activities. However, driving and reading will be affected.

 
             
Age-Related Macular Degeneration

What causes Age-Related Macular Degeneration?

Age-related macular degeneration (AMD) occurs in 'dry' and 'wet' forms. In dry AMD─the most common form─the light-sensitive cells in the macula slowly break down, blurring central vision in the affected eye. The exact cause of dry AMD is unknown, but the condition develops as the eye ages. In the 'wet' form, abnormal blood vessel growth in the eye leads to the leaking of blood and proteins into the sensitive cells (called photoreceptors) in the macula, damaging them and causing vision loss. The wet form is the condition in its advanced stage.

How do I know if I have Age-Related Macular Degeneration?

You may have one of some of these symptoms:

  • Gradual or rapid on set of blurred vision, especially in your central vision
  • Shadows or missing areas of vision
  • Distorted vision, e.g., a grid of straight lines appears wavy and parts of the grid may appear blank
  • Problems discerning colours, specifically dark colours from other dark colours and light colours from other light colours
  • Slow recovery of visual function after exposure to bright light
  • Loss in contrast sensitivity (ability to tell different levels of luminaries or brightness apart)

What puts me at risk of Age-Related Macular Degeneration?

Your risk increases with:

  • Age: There are no current figures on how many Singaporeans have AMD but a community study in 1997 showed that one in four people aged 60 and above here suffered from the condition
  • A positive family history
  • Gender: Women are more likely to develop AMD
  • Smoking
  • Obesity
  • Cardiovascular diseases

What can I do to prevent Age-Related Macular Degeneration?

There are no proven preventive medications for AMD. The best way to prevent vision loss is to get a prompt eye examination and diagnosis by your eye doctor. Early diagnosis improves the success of treatment. Using a screening tool called the Amsler grid may help detect subtle changes in your vision. You can monitor your vision daily by looking at an Amsler grid. You should also stop smoking, eat a balanced diet that includes leafy green vegetables, and protect your eyes from UV light by wearing protective sunglasses or head gear with brims.

Amsler Grid Chart

What kinds of treatments are available for Age-Related Macular Degeneration?

  • Laser photocoagulation:  A surgical procedure involving the application of a hot laser
  • Photo Dynamic Therapy: This method uses a non-thermal laser together with an intravenous drug to seal and halt or slow the progression of the condition
  • Drugs: Macugen and Lucentis are two drugs delivered to the eye through injections.

Your eye doctor will be able to advise you on the best course of treatment for your AMD.
 
Please visit the following relevant links:

Vitreo-Retina Service
Outcome Results on Vitreo-Retina Procedure
Vitreo-Retina Clinical Staff
I Want an Eye Examination / an Appointment
How the Eye Works
Feedback


Where to Seek Treatment

The medical institutions within SingHealth that offer consultation and treatment for this condition include:

1. Singapore National Eye Centre
Vitreo-Retina Service
11 Third Hospital Avenue, Singapore 168751

Appointments Hotline:
Tel : +65 6227 7266

International Enquiries, please contact:
Tel : +65 6100 9393
Email : ips@snec.com.sg
2. KK Women's and Children's Hospital
Children's - KK Eye Centre
100 Bukit Timah Road Singapore 229899

Appointments Hotline:
Tel : +65 6294 4050

International Enquiries, please contact:
Tel : +65 6394 8888
Email : international@kkh.com.sg


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