NNI Neuroimmunology and Neuroinfectious Disease Service and Research

Regional Tertiary Referral Centre

As a tertiary referral centre for neurological disease in Singapore and the South East Asia region, the National Neuroscience Institute (NNI) has enhanced its services in Neuroimmunology and Neuroinfectious disease.

There is now a weekly Neuroimmunology and Neuroinfectious disease sub-specialty clinic available for the management of autoimmune or infective neurological disorders. Inpatients with complex neuroimmune and neuroinfectious disorders can also be referred for evaluation.

NNI is also developing its capability for research in autoimmune neurological disorders. The Neuroimmunology Database and Tissue Repository was set up in 2007 to aid in the study of these diseases. It is a repository of DNA, blood cells, plasma, serum and cerebrospinal fluid (CSF) linked to a comprehensive database of euroimmunological conditions such as Multiple Sclerosis and other autoimmune disease which causes central nervous system demyelination.

This standing database will describe phenotype, demographics, risk factors, results of diagnostic tests performed, and pedigree/family history of similar conditions. Blood and CSF will be collected and banked during routine diagnostic investigations. Banked tissue will be used for future research studies. A similar database and tissue repository of patients with Guillain-Barré Syndrome is currently being set up.

1st Multi-centred Multiple Sclerosis-related Trial

In the area of clinical trials, NNI will, this year also be participating for the first time in a multi-centre, randomised, placebo-controlled MS-related trial. This trial aims to treat patients with the first clinical demyelinating event suggestive of Multiple Sclerosis with an oral agent to delay subsequent relapses and disability.

Making An Appointment
National Neuroscience Institute
Tel : (65) 6357 7095
Fax : (65) 6357 7103
Website : www.nni.com.sg